Depression, Postpartum Clinical Trial
Official title:
Chronic Stress Protection for Post-natal Depression Prevention: An Exploratory Study
The risk of emergence of a post natal depression is based on an interaction between a
maternal psychic vulnerability and a chronic environmental context of stress. The PND appears
as a relevant model for studying the mechanisms of chronic stress and vulnerability to
psychological pathologies.
This study aim to follow a cohort of pregnant women to determine the predictive
psychobiological factors of the emergence of postnatal depression
The prevalence of postnatal depression is high in civilian settings (20%). In mechanistic
terms, the risk of emergence of a post natal depression is based on an interaction between a
maternal psychic vulnerability and a chronic environmental context of stress. The post natal
depression appears as a relevant model for studying the mechanisms of chronic stress and
vulnerability to psychological pathologies.
- On the one hand, the repetition of stressors during pregnancy corresponds to a natural
chronic stress model of several months and thus allows to study the biological cost of
responses to repeated stresses, and the adaptive mechanisms leading to From functional
drift to psychic dysfunction.
- On the other hand, isolated vulnerability factors characterize a mirroring psychological
profile of a Mindfulness type of functioning. Mindfulness or full consciousness has been
described as a state of consciousness which results from intentionally, at the present
moment, without judging the experience that unfolds moment by moment. This psychological
resource has been associated with resilient or even resilient psychic functioning.
This study aim to follow a cohort of pregnant women from the first trimester of pregnancies
to 2 months after the delivery to determine the predictive psychobiological factors of the
emergence of postnatal depression
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