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Clinical Trial Summary

The goal of this neuroimaging pilot study is to understand developmental differences in the impact of therapeutic wavelength light (blue light) versus a non-therapeutic wavelength (red light) on emotional brain function in depression. The main questions this study aims to answer are: - Does acute exposure to blue light (vs red light) stabilize emotional brain function in depressed individuals? - Are stabilizing effects of blue light (vs red light) stronger for blue light in adolescents than young adults? Participants will complete: - A magnetic resonance imaging brain scan, in which we will examine the effect of blue versus red light on emotional brain function at rest and in response to rewards and losses. - A pupillometry test of sensitivity to blue vs red light - Clinical interviews and surveys - Screening measures for drug and alcohol use, MRI safety, and current pregnancy [if relevant] - Home sleep tracking with sleep diary and actigraphy for one week


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05712772
Study type Interventional
Source University of Pittsburgh
Contact Adriane M Soehner, PhD
Phone 4122466651
Email soehneram2@upmc.edu
Status Recruiting
Phase N/A
Start date June 14, 2023
Completion date July 31, 2024

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