Clinical Trials Logo

Dental Caries clinical trials

View clinical trials related to Dental Caries.

Filter by:

NCT ID: NCT04147091 Completed - Caries,Dental Clinical Trials

Nano-hydroxyapatite and Ozone - Effect on Approximal Initial Caries

Start date: February 2012
Phase: Phase 2/Phase 3
Study type: Interventional

Objectives: to assess the efficiency of three methods of enamel remineralization on initial approximal caries: 1. a nano-hydroxyapatite gel, 2. gaseous ozone therapy 3. combination of a nano-hydroxyapatite gel and ozone. Materials and Methods: Patients (n=92, age 20-30y) with initial approximal enamel lesions on premolar and molar teeth (n=546) randomly allocated to three groups subjected to a 6-months treatment: Group I: domestic nano-hydroxyapatite remineralizing gel, group II: in-office ozone therapy, group III: both remineralizing gel and ozone therapy. Caries lesions assessed on bitewing radiographs at baseline, after 1 year and after 2 years.

NCT ID: NCT04145102 Completed - Dentin Caries Clinical Trials

Evaluation of the Remineralizing and Antibacterial Effect of Natural Versus Synthetic Materials on Deep Carious Dentin

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

The present study will be performed to evaluate: 1. The remineralizing effect of natural materials versus synthetic materials on deep carious dentin after selective caries removal. 2. The antibacterial effect of natural materials versus synthetic materials on deep carious dentin.

NCT ID: NCT04136639 Completed - Dental Caries Clinical Trials

The Anticariogenic Effect of Miswak (Silvadora Persica) and Grape Seed Extract

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

Prevention of dental caries has taken a great importance in the last decade. The use of herbal and natural products became mandatory to avoid the side effects of commercially available medications. Aim of the study; the aim was to investigate the anti-cariogenic effect of miswak and grape seed extract (GSE).

NCT ID: NCT04127929 Completed - Dental Caries Clinical Trials

Investigation of Glass Carbomer Performance

Start date: September 9, 2017
Phase: N/A
Study type: Interventional

The aim of this in vivo study was to evaluate the clinical 1 year follow-up of silica and flouroapatite reinforced glass carbomer filling material.

NCT ID: NCT04127357 Completed - Clinical trials for Dental Caries in Children

Progression of Active Microcavitated Carious Lesions on Primary Molar Occlusal Surfaces

Start date: March 5, 2015
Phase: N/A
Study type: Interventional

Objective: To verify the progression of active microcavitated carious lesions on occlusal surfaces of primary molars after the orientation of the brushing technique associated with fluoride dentifrice compared to resin sealant, through a 12-month randomized clinical trial. Methodology: We selected 22 children from 4 to 9 years old from the public school system of the city of Juazeiro do Norte-Ceará, with at least one primary molar presenting an active caries lesion score 3 of the International Caries Detection and Assessment System (ICDAS). Randomization was performed en bloc and stratified by two conditions (age and caries experience). The selected teeth were divided into two groups: the first (G1) was submitted to brushing with fluoridated toothpaste; and the other group (G2) to the resin sealing technique, whose application of the material was performed under absolute or relative isolation, selected through a second randomization. The molars undergoing treatment were evaluated at 6- and 12-month returns. Caries progression was evaluated according to the type of treatment, dental group and sealant retention by the Chi-square test. For cost analysis, the variance test (ANOVA) was used.

NCT ID: NCT04126928 Completed - Clinical trials for Apical Periodontitis

Validation of PUFA Index in Assessing Untreated Dental Caries Among Malaysian Adult Subpopulation

Start date: September 10, 2015
Phase: N/A
Study type: Interventional

PUFA Index was introduced to detect the clinical consequences of untreated dental caries. To date, there are no studies on the reliability and accuracy of the PUFA index as a screening tool. Other than indices, radiographs were sometimes used as a screening tool using the validated Periapical Index (PAI). The aim of this study was to evaluate the reliability and accuracy of PUFA and PAI in screening for clinical outcomes of untreated caries, specifically pulpal and periapical diseases. The reference standard is the clinical diagnosis, as categorized by the American Association of Endodontists. Intra- and inter-examiner reliability will be determined using Cohen's kappa. Sensitivity, specificity, positive predictive value, and negative predictive value will be calculated. Receiver Operating Characteristics (ROC) contrast estimation will be computed to compare the two index tests.

NCT ID: NCT04122508 Completed - Anxiety Clinical Trials

Are Dental Neglect and the Siblings Risk Factors in Children

Start date: January 1, 2019
Phase:
Study type: Observational

Neglect insidiously affects a child's overall health in all aspects. The aim of this study was to determine whether the presence of siblings caused dental neglect, and whether there was a relationship between dental neglect and anxiety.

NCT ID: NCT04107012 Completed - White Spot Lesion Clinical Trials

Evaluation of Enamel Demineralization During Clear Aligner Orthodontic Treatment

Start date: September 2016
Phase: N/A
Study type: Interventional

Development of white spot lesions (enamel demineralization) will be evaluated quantitatively during clear aligner orthodontic treatment compared to conventional fixed appliances using quantitative light induced fluorescence (QLF)

NCT ID: NCT04101617 Completed - Dental Caries Clinical Trials

Improving Dental Health Among Toddlers in the Dominican Republic

Start date: February 13, 2019
Phase: N/A
Study type: Interventional

Caries prevalence in the Dominican Republic (DR) seems high, although recent information is lacking. In DR there is a growth and development program for all children from the age of 0 to 5.Even though there is a mandatory educational health program for children and parents in this program, where periodically pediatricians examine them, this program does not include oral health education/prevention. Thus, it is proposed A) to devise materials to be used by pediatricians to share relevant information about caries control to parents of toddlers, and B) to evaluate the impact of such material on caries prevention for groups of toddlers over a 1.5-year period. Educational material will be developed for parents, and the pediatricians will deliver this material to 10-months-old children randomly selected at Plaza de la Salud Hospital. The PI will train the pediatricians in caries prevention and how to deliver the information to the parents in a clear manner. A total of 306 will be allocated into two groups. The experimental group (128 children) will receive the devised educational materials at 10 months, follow-up information will be provided at growth and development visits when the child is 18-, and 24 months old. The second group will be considered as the control group and will not receive any educational materials (178 children). All the enrolled children will receive fluoride containing toothpaste and tooth brushes. After 18 months when the children will be about 3 years old they will be examined to assess dental caries status. A sample mortality rate of 40% is expected during the two-year follow-up. Differences in caries status between the two groups will be examined using Welch's independent t-tests for unequal variances.

NCT ID: NCT04081025 Completed - Quality of Life Clinical Trials

Oral Health and Risk Factors for Oral Disease

Start date: January 1, 2018
Phase:
Study type: Observational

Oral health has improved considerably in recent decades in Sweden, as well as in other countries. However, despite great improvements with regard to periodontal disease and dental caries in recent decades, global problems still persist, and as a consequence of retaining natural teeth high up in age, the risk for oral disease increases.