The Appropriate Level of Continuous Adductor Canal Block in Patients Undergoing Total Knee Arthroplasty (TKA)

Degenerative Arthritis Clinical Trial

Official title:

The Appropriate Level of Continuous Adductor Canal Block in Patients Undergoing Total Knee Arthroplasty (TKA)

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04206150
• Other study ID #: 4-2019-1038
• Status: Completed
• Phase: N/A
• Start date: April 2, 2020
• Est. completion date: July 17, 2021

Study information

• Verified date: October 2021
• Source: Yonsei University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Adductor canal catheters are being used to provide continuous postoperative analgesia after total knee arthroplasty surgery (TKA). There is much debate about where is the best position of continuous adductor canal block in patients undergoing TKA. Therefore, the investigators aim to compare the postoperative pain at three different level of continuous adductor canal block. Ninety six patients scheduled for total knee arthroplasty will be randomly divided into the three groups. In group 1, the adductor canal catheter is inserted at femoral triangle apex (the proximal end of the adductor canal). In group 2, the adductor canal catheter is inserted femur length/15*2 cm above the location where the nerve block performed in group 1. In group 3, the adductor canal catheter is inserted femur length/15cm below the location where the nerve block performed in group 1.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 96
• Est. completion date: July 17, 2021
• Est. primary completion date: July 16, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 50 Years and older

Eligibility

Inclusion Criteria:

• 1. Patients undergoing total knee arthroplasty

Exclusion Criteria:

• 1. Patients who have infection or had surgery on the thigh
• 2. The subject is a foreigner or illiterate
• 3. Patients who have cognitive dysfunction

Related Conditions & MeSH terms

• Degenerative Arthritis
• Osteoarthritis

Intervention

Procedure:
• the three different sites of continous adductor canal block: the adductor canal catheter is inserted at femoral triangle apex
In group 1, the adductor canal catheter is inserted at femoral triangle apex (the proximal end of the adductor canal).
• the three different sites of continous adductor canal block: the adductor canal catheter is inserted femur length/15*2 cm above the location
In group 2, the adductor canal catheter is inserted femur length/15*2 cm above the location where the nerve block performed in group 1.
• the three different sites of continous adductor canal block: the adductor canal catheter is inserted femur length/15 cm below the location
In group 3, the adductor canal catheter is inserted femur length/15 cm below the location where the nerve block performed in group 1.

Locations

Country	Name	City	State
Korea, Republic of	Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei Universiy College of Medicine	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Yonsei University

Country where clinical trial is conducted

Korea, Republic of, 

References & Publications (2)

Chuan A, Lansdown A, Brick KL, Bourgeois AJG, Pencheva LB, Hue B, Goddard S, Lennon MJ, Walters A, Auyong D; Continuous Catheters in Adductor Canal versus Femoral Triangle (The CAFE study) investigators. Adductor canal versus femoral triangle anatomical locations for continuous catheter analgesia after total knee arthroplasty: a multicentre randomised controlled study. Br J Anaesth. 2019 Sep;123(3):360-367. doi: 10.1016/j.bja.2019.03.021. Epub 2019 May 2. — View Citation

Sztain JF, Khatibi B, Monahan AM, Said ET, Abramson WB, Gabriel RA, Finneran JJ 4th, Bellars RH, Nguyen PL, Ball ST, Gonzales FB, Ahmed SS, Donohue MC, Padwal JA, Ilfeld BM. Proximal Versus Distal Continuous Adductor Canal Blocks: Does Varying Perineural Catheter Location Influence Analgesia? A Randomized, Subject-Masked, Controlled Clinical Trial. Anesth Analg. 2018 Jul;127(1):240-246. doi: 10.1213/ANE.0000000000003422. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pain : Visual Analogue Scale (VAS) for pain	The visual analog scale(VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" (0) and "worst pain." (10). The ends are defined as the extreme limits of the parameter to be measured(symptom,pain,health) orientated from the left(0, worst) to the right(10, best).	Baseline (Before surgery)
Primary	Pain : Visual Analogue Scale (VAS) for pain	The visual analog scale(VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" (0) and "worst pain." (10). The ends are defined as the extreme limits of the parameter to be measured(symptom,pain,health) orientated from the left(0, worst) to the right(10, best).	postoperative day 1
Primary	Pain : Visual Analogue Scale (VAS) for pain	The visual analog scale(VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" (0) and "worst pain." (10). The ends are defined as the extreme limits of the parameter to be measured(symptom,pain,health) orientated from the left(0, worst) to the right(10, best).	postoperative day 2
Secondary	muscle strength	Quadriceps strength of both legs was assessed by placing the dynamometer on the anterior of the ankle, between the malleoli.	Baseline (Before surgery)
Secondary	muscle strength	Quadriceps strength of both legs was assessed by placing the dynamometer on the anterior of the ankle, between the malleoli.	postoperative day 1
Secondary	muscle strength	Quadriceps strength of both legs was assessed by placing the dynamometer on the anterior of the ankle, between the malleoli.	postoperative day 2