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Combined Administration of Intravenous and Topical Tranexamic Acid in Total Knee Arthroplasty

Degenerative Arthritis Clinical Trial

Official title:
Combined Administration of Intravenous and Topical Tranexamic Acid in Total Knee Arthroplasty: Is it the Most Effective Regime? A Randomized Controlled Trial.

Clinical Trial Summary

This prospective randomized controlled trial was conducted To compare the efficacy of TNA in terms of total blood loss and the allogenic transfusion rate among the three study groups; intravenous alone, combined intravenous and low dose topical TNA and combined intravenous and high dose topical TNA.

To evaluate the safety of each regimen in view of deep vein thrombosis and venous thromboembolism.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02286973
Study type Interventional
Source Seoul National University Hospital
Contact TaeKyun Kim, MD,PhD
Phone 082-031-787-3355
Email osktk@gmail.com
Status Not yet recruiting
Phase Phase 1
Start date November 2014
Completion date June 2015
View Details
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