Deep Vein Thrombosis Clinical Trial
Official title:
Ultrasound Elastography: a New Technique to Diagnose Acute and Chronic Deep Vein Thrombosis
In clinical practice, compression ultrasound (CUS) has become an easy and reliable
noninvasive tool for the diagnosis of deep vein thrombosis (DVT).
Currently there are not validated methods to assess the biological age of venous thrombus,
and the date of onset of thrombosis. One potential technique to age DVT is ultrasound
elastography (UE). UE is a noninvasive technique to measure tissue hardness, and it is well
known that thrombi harden as they age. The aim of this study will be to assess the ability of
UE to distinguish acute from chronic DVT. The investigators will evaluate prospectively all
consecutive outpatients presenting with clinically suspected unprovoked DVT of the lower
limbs, and those having a previous diagnosis of DVT for the scheduled 3 months visit of
follow-up, for a period of about one year. All the enrolled patients will undergo to the CUS
of the lower limbs, and at the same time to the ultrasound elastography by the physician
expert in vascular ultrasound. The specialist performing both examinations will be unaware of
the time of onset of DVT (acute or chronic). Then the patients will be divided into two
groups (group A: patients with acute DVT; group B: patients with chronic DVT at the 3rd month
of follow-up). Each examination (CUS and ultrasound elastography) will be repeated three
times in the same patient at the same visit, to assess the reproducibility of the technique.
The demographic data, medical history, physical examination and the results of CUS and
ultrasound elastography will be collected in a case report form (CRF) by another investigator
who does not perform the examinations. The blinded CRF will be submitted to a dedicated
committee for statistical analysis.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05003843 -
BOLT: Study of the Indigo® Aspiration System When Used in Patients With Deep Vein Thrombosis
|
N/A | |
| Recruiting |
NCT03937947 -
Traumatic Brain Injury Associated Radiological DVT Incidence and Significance Study
|
||
| Withdrawn |
NCT04136561 -
Novel Strategy to Encourage Early Removal of Central Venous Catheters
|
N/A | |
| Completed |
NCT03420625 -
Blood Flow Stimulation in the Lower Limbs by Application of Different External Devices
|
N/A | |
| Recruiting |
NCT02507180 -
Safely Ruling Out Deep Vein Thrombosis in Pregnancy With the LEFt Clinical Decision Rule and D-Dimer
|
||
| Completed |
NCT02555111 -
Xarelto Versus no Treatment for the Prevention of Recurrent Thrombosis in Patients With Chronic Portal Vein Thrombosis.
|
Phase 3 | |
| Completed |
NCT01975090 -
The SENTRY Clinical Study
|
N/A | |
| Terminated |
NCT02469376 -
Evaluation of a New Imagingtechnologie for Thrombosis
|
Phase 1 | |
| Completed |
NCT02037607 -
Incidence of Venous Thromboembolism in Children Undergoing Elective Neurosurgical Procedures
|
N/A | |
| Not yet recruiting |
NCT01357941 -
Need for Antepartum Thromboprophylaxis in Pregnant Women With One Prior Episode of Venous Thromboembolism (VTE)
|
N/A | |
| Completed |
NCT00773448 -
Screening for Occult Malignancy in Patients With Idiopathic Venous Thromboembolism
|
N/A | |
| Completed |
NCT00720915 -
D-dimer to Select Patients With First Unprovoked Venous Thromboembolism Who Can Have Anticoagulants Stopped at 3 Months
|
N/A | |
| Completed |
NCT00771303 -
Ruling Out Pulmonary Embolism During Pregnancy:a Multicenter Outcome Study
|
||
| Completed |
NCT00244725 -
Odiparcil For The Prevention Of Venous Thromboembolism
|
Phase 2 | |
| Completed |
NCT00264277 -
D-dimer to Establish Duration of Anticoagulation After Venous Thromboembolism
|
Phase 4 | |
| Completed |
NCT00365950 -
3 Months' Versus 6 Months' Anticoagulation in Patients With DVT and/or PE
|
Phase 4 | |
| Completed |
NCT00182403 -
Fixed Dose Heparin Study
|
Phase 3 | |
| Completed |
NCT03682419 -
Evaluation of Precision and Accuracy of INR Measurements in a Point of Care Device (OPTIMAL)
|
N/A | |
| Not yet recruiting |
NCT04981327 -
The API-CALF Study: Apixaban to Treat Calf Vein Thrombosis
|
Phase 3 | |
| Recruiting |
NCT03240120 -
A Study of Dabigatran Etexilate as Primary Treatment of Malignancy Associated Venous Thromboembolism
|
Phase 3 |