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Cystic Fibrosis Related Diabetes Screening. — D2M  

Cystic Fibrosis-related Diabetes Clinical Trial

Official title:
Sensitivity and Specificity of Different Methods for Cystic Fibrosis-related Diabetes Screening.

Clinical Trial Summary

Cystic fibrosis-related diabetes is a late cystic fibrosis (CF) associated comorbidity whose prevalence is increasing sharply lifelong. Guidelines for glucose metabolism (GM) monitoring relies on oral glucose tolerance test . However, this test is neither sensitive nor specific.

The aim of this study is to compare sensitivity and specificity of different methods for GM monitoring in children and adolescents with CF.

Continuous GM system (CGMS) will be used as the reference method. Results will be compared to those of oral glucose tolerance test (OGTT), intravenous glucose tolerance test (IGTT), homeostasis model assessment index of insulin resistance (HOMA-%IR) , homeostasis model assessment index of beta-cell function (HOMA-%B) and HbA1C dosage (glycated haemoglobin A1C). Patients will be classified into three groups according to CGMS: normal glucose tolerance, impaired glucose tolerance and diabetes mellitus.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02723968
Study type Interventional
Source Hospices Civils de Lyon
Contact
Status Completed
Phase N/A
Start date September 2009
Completion date April 2012
View Details
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