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NCT ID: NCT04356456 Withdrawn - Skin Clinical Trials

A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Nutritional Supplement Lumenato and Its Impact on Skin Parameters in Healthy Female Subjects

Start date: January 14, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate perceived changes in skin health and appearance after taking the study product daily for 12 weeks. The study product is a soft gel supplement containing tomato oil. cored Lumenato supplement on skin health and appearance.

NCT ID: NCT04354727 Withdrawn - Myelofibrosis Clinical Trials

A Study of APG-1252 in Patients With Myelofibrosis Who Progressed After Initial Therapy

Start date: December 15, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

The study is a designed to evaluate safety and activity of APG-1252 when administered as monotherapy and in combination with ruxolitinib in previously ruxolitinib treated myelofibrosis patients.

NCT ID: NCT04353505 Withdrawn - Chronic Migraine Clinical Trials

Intra-arterial Sphenopalatine Ganglion Block for Patients With Refractory Headache

Start date: October 2020
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of intra-arterial (IA) delivery of Dexamethasone and Ketorolac into the arteries supplying the sphenopalatine ganglion (SPG) - a collection of neurons that plays an important role in headache disorders - in patients with refractory migraine, cluster headache and trigeminal neuralgia. All patients must fail standard treatments prior to enrollment in the trial.

NCT ID: NCT04351230 Withdrawn - Clinical trials for Anatomic Stage IV Breast Cancer AJCC v8

T-DM1 With or Without Abemaciclib for the Treatment of HER2-Positive Metastatic Breast Cancer

Start date: November 11, 2020
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well T-DMI with or without abemaciclib works for the treatment of HER2-positive breast cancer that has spread to other places in the body (metastatic). T-DM1 is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug called DM1. Trastuzumab attaches to HER2 positive cancer cells in a targeted way and delivers DM1 to kill them. Abemaciclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving T-DM1 and abemaciclib may work better in treating patients with breast cancer compared to T-DM1 alone.

NCT ID: NCT04351061 Withdrawn - Clinical trials for Cerebrospinal Fluid Leak

Acetazolamide for the Prevention of Post Operative CSF Leak

Start date: May 7, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this research is to test the use of Acetazolamide in preventing post-operative cerebrospinal fluid leak in patients having endoscopic skull base surgery (it is a surgery performed through the nose and sinus).

NCT ID: NCT04350450 Withdrawn - COVID-19 Clinical Trials

Hydroxychloroquine Treatment of Healthcare Workers With COVID19 Illness at Montefiore

Start date: April 2020
Phase: Phase 2
Study type: Interventional

Given the high prevalence of COVID19 illness (both SARS-CoV-2 RT-PCR confirmed and highly suspect cases) among healthcare workers (HCW) within the Montefiore Health System (MHS), hydroxychloroquine (HCQ) will be prescribed to healthcare workers who are at the highest risk for severe COVID19 illness.

NCT ID: NCT04349930 Withdrawn - Clinical trials for Interstitial Cystitis

The CBD-IC Randomized Controlled Trial: Evaluation of Hemp Cannabidiol SuppositoRies for Pain and Urinary SymptOms in INterstitial Cystitis (CHRONIC)

CHRONIC
Start date: January 2021
Phase: Phase 1
Study type: Interventional

This study seeks to exploit bladder cannabidiol receptors as a therapeutic drug target by conducting a double-masked, placebo-controlled randomized trial evaluating the effects of vaginal hemp cannabidiol (CBD) suppositories on lower urinary tract symptoms (LUTS), pain severity, and sexual function.

NCT ID: NCT04349774 Withdrawn - Pain, Postoperative Clinical Trials

Erector Spinae Plane Block vs Erector Spinae Plane Block With Serratus Anterior Plane Block in Thoracic Surgery

Start date: October 1, 2022
Phase: Phase 4
Study type: Interventional

This pilot study will prospectively compare continuous Erector Spinae Plane block (ESP) versus combination of continuous Erector Spinae Plane block and single shot Serratus Anterior Plane block for post-operative pain management in subjects undergoing primary thoracic surgery.

NCT ID: NCT04349332 Withdrawn - Clinical trials for Mechanical Ventilation

Early Extubation for Patients With Acute Hypoxemic Respiratory Failure

Start date: August 13, 2020
Phase: N/A
Study type: Interventional

The objective of the study is to evaluate the efficacy of helmet NIV in reducing the duration of invasive mechanical ventilation in order to minimize ventilator needs during the COVID-19 pandemic.

NCT ID: NCT04347135 Withdrawn - Endometriosis Clinical Trials

Evaluating Endometriosis With 16α-(18)F-fluoro-17β-estradiol ([F-18] FES) PET/MRI

Start date: October 7, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

Researchers are trying to improve the detection of endometriosis using F-18 FES PET/MRI imaging.