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NCT ID: NCT04146909 Terminated - Lactation Clinical Trials

The Effect of Lactation on Insulin Sensitivity and Lipolysis in Women

Start date: November 17, 2020
Phase: N/A
Study type: Interventional

This purpose of this study is to investigate whether lactation improves insulin sensitivity and increases lipolysis in women.

NCT ID: NCT04146779 Terminated - Clinical trials for Head and Neck Cancer

Yoga Intervention in Head and Neck Cancer Patients Undergoing Concurrent Chemo-Radiation

Start date: October 28, 2019
Phase: N/A
Study type: Interventional

This is a randomized prospective pilot study assessing the safety and feasibility of two yoga interventions in head and neck cancer patients undergoing primary or adjuvant radiation with or without concurrent chemotherapy

NCT ID: NCT04146012 Terminated - Clinical trials for Renal Insufficiency,Chronic

BEACH Trial: Bovine Early Access, Compatibility and Hemostasis Trial

BEACH
Start date: December 3, 2019
Phase: Phase 3
Study type: Interventional

Bovine Early Access, Compatibility, and Hemostasis (BEACH) Trial Study is to evaluate the Safety and Effectiveness of Early Access in Patients Who Require an Arteriovenous Conduit for Hemodialysis using the Artegraft® Collagen Vascular Graft™. The objective of the BEACH Trial is to demonstrate that early access of Artegraft is associated with acceptable rates of successful early access, and acceptable rates of a composite of adverse events, to support a modification of existing device labeling stating that Artegraft is capable of cannulation within 72 hours post implantation.

NCT ID: NCT04145700 Terminated - Synovial Sarcoma Clinical Trials

CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Synovial Sarcoma

Start date: March 4, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

This study is being conducted to test the safety and efficacy of ramucirumab in combination with other chemotherapy in the treatment of relapsed, recurrent, or refractory synovial sarcoma (SS) in children and young adults. This trial is part of the CAMPFIRE master protocol (NCT05999994) which is a platform to accelerate the development of new treatments for pediatric and young adult participants with cancer. Your participation in this trial could last 12 months or longer, depending on how you and your tumor respond.

NCT ID: NCT04145037 Terminated - Gaucher Disease Clinical Trials

Lentiviral Vector Gene Therapy - The Guard1 Trial of AVR-RD-02 for Subjects With Type 1 Gaucher Disease

Start date: May 30, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This was a multinational, open-label study to assess the safety and efficacy of AVR-RD-02 in approximately 8 to 16 subjects (male or female) who are ≥18 and ≤50 years of age and post pubertal at Screening with a confirmed diagnosis of Type 1 Gaucher disease (based on clinical phenotype, genotyping, and deficient GCase enzyme activity in whole blood).

NCT ID: NCT04144140 Terminated - Lymphoma Clinical Trials

Study of Intratumorally Administered Stimulator of Interferon Genes (STING) Agonist E7766 in Participants With Advanced Solid Tumors or Lymphomas - INSTAL-101

Start date: February 24, 2020
Phase: Phase 1
Study type: Interventional

This is an open label, multicenter, phase 1/1b study to assess safety/tolerability and preliminary clinical activity of E7766 as a single agent administered intratumorally in participants with advanced solid tumors or lymphomas.

NCT ID: NCT04142658 Terminated - Clinical trials for Aortic Valve Stenosis

PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban

Start date: May 1, 2020
Phase: Phase 3
Study type: Interventional

Currently, warfarin is the only approved anticoagulation for patients with mechanical valves. The purpose of this study is to determine if participants with an On-X Prosthetic Heart Valve / On-X aortic valve can be maintained safely and effectively on apixaban. Both the On-X aortic valve and apixaban have been approved for use by the US Food and Drug Administration (FDA) but they have not been approved to be used together.

NCT ID: NCT04142619 Terminated - Clinical trials for Relapsed/Refractory Multiple Myeloma

Study Evaluating Safety and Efficacy of UCART Targeting CS1 in Patients With Relapsed/Refractory Multiple Myeloma (MELANI-01)

Start date: November 21, 2019
Phase: Phase 1
Study type: Interventional

This is a Phase I, FIH, open-label, dose escalation study evaluating Safety and Efficacy of UCART targeting CS1 in patients with Relapsed or Refractory Multiple Myeloma (MM). The purpose of this study is to evaluate the safety and clinical activity of UCARTCS1A and to determine the Maximum Tolerated Dose (MTD).

NCT ID: NCT04142359 Terminated - Pharmacokinetics Clinical Trials

PK Sub-Study of QUILT-3.032 (CA ALT-803-01-16) and of QUILT-2.005 (CA ALT-803-01-14)

Start date: October 11, 2019
Phase:
Study type: Observational

Non-interventional PK sub-study of QUILT-3.032 (CA-ALT-803-01-16) and QUILT-2.005 (CA-ALT-803-01-14)

NCT ID: NCT04141917 Terminated - Influenza Clinical Trials

Test-and-treat for Influenza in Homeless Shelters

Start date: November 15, 2019
Phase: Phase 4
Study type: Interventional

This study is a stepped-wedge cluster-randomized trial of on-site rapid testing and treatment for influenza in homeless shelters within the Seattle area to determine whether this strategy reduced the incidence of influenza in the shelter environment.