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NCT ID: NCT05631548 Completed - Clinical trials for Cocaine Use Disorder

Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder (Pilot Study)

Start date: February 23, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effects of active intermittent theta burst stimulation (iTBS) to dorsomedial prefrontal cortex (dmPFC) on electroencephalogram (EEG) measures of reward sensitivity and cue reactivity and cocaine craving in cocaine users

NCT ID: NCT05631119 Completed - Healthy Clinical Trials

Biorepository of Biospecimen Samples in Matched Healthy Control Participants and Participants Diagnosed With Diabetic Kidney Disease, Chronic Kidney Disease, or Type 2 Diabetes

SAN-08961
Start date: December 15, 2022
Phase:
Study type: Observational [Patient Registry]

The Investigators will generate a repository of human biosamples across therapeutic areas that will be used to identify disease-associated biomarkers and potential targets with immune and multi-omics profiling. This sample collection and analysis from people living with type 2 diabetes, or chronic or diabetic kidney disease will lay the groundwork for an extensive network of biosample access and linked datasets that will provide an invaluable resource for translational research.

NCT ID: NCT05630729 Completed - Clinical trials for Chronic Kidney Diseases

Living With CKD: An E-Learning Platform for Adolescents With CKD About the Disease and Its Management

CKD Delp
Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Leveraging a unique combination of synchronized web and mobile applications, this 3 year SBIR Phase II project will fully develop and pilot test My Kidney Guru-a program that will offer pediatric patients with CKD developmentally appropriate, interactive, and engaging instruction and practice opportunities to build knowledge and skills to manage CKD.

NCT ID: NCT05630677 Completed - Healthy Volunteers Clinical Trials

A Study to Compare Bioavailability of AZD5055 Film-coated Tablet With AZD5055 Oral Suspension and to Assess the Effect of Food and an Acid Reducing Agent on Pharmacokinetics (PK) of AZD5055 in Healthy Subjects.

Start date: November 4, 2022
Phase: Phase 1
Study type: Interventional

This study will estimate the relative bioavailability of AZD5055 film-coated tablet as compared to AZD5055 oral suspension. The study will also assess the absolute bioavailabilty of AZD5055 and the effect of food and an acid reducing agent, rabeprazole, on the PK of AZD5055 film-coated tablets when given with food (fed state) or without food (fasted state).

NCT ID: NCT05630365 Completed - COVID-19 Clinical Trials

Clinical Evaluation of the Panbio™ COVID-19/Flu A&B Rapid Panel Professional Use Product Using Mid-Turbinate Nasal Swabs

Start date: December 15, 2022
Phase: N/A
Study type: Interventional

This study is designed as an international, prospective, multicentric, clinical study to investigate the performance of the Panbio™ COVID-19/Flu A&B Rapid Panel for the qualitative detection of COVID-19 antigen, Influenza A antigen, and Influenza B antigen in human mid-turbinate nasal swabs collected by a trained health worker. This study is part of the performance evaluation to support the CE conformity assessment procedures.

NCT ID: NCT05630287 Completed - Healthy Clinical Trials

A Study of Absorption, Metabolism, Excretion, and Absolute Bioavailability of Carbon-14-Labelled [14C] Selpercatinib (LY3527723) in Healthy Male Participants

Start date: August 1, 2018
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to compare the amount of selpercatinib that gets into the blood stream and how long it takes the body to get rid of it and also to assess the pharmacokinetics (PK), metabolism, and routes and extent of elimination of selpercatinib in healthy male participants. The study will last up to 59 days (Part 1) or 46 days (Part 2) including screening and 7-day safety follow-up.

NCT ID: NCT05630274 Completed - Healthy Clinical Trials

A Study of Effect of Selpercatinib (LY3527723) on Corrected QT (QTc) Interval in Healthy Participants

Start date: April 16, 2019
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to assess the effect of Selpercatinib (LY3527723) on the heart rate-corrected QT (QTc) interval. The study will last up to 41 days.

NCT ID: NCT05630196 Completed - Clinical trials for Chronic Low-back Pain

A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Chronic Low Back Pain

Start date: December 8, 2022
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to assess whether LY3857210 is safe and efficacious in relieving chronic low back pain (CLBP). This trial is part of the chronic pain master protocol (H0P-MC-CPMP) which is a protocol to accelerate the development of new treatments for chronic pain.

NCT ID: NCT05630170 Completed - Clinical trials for Left Ventricular Systolic Dysfunction

The SMART-LV Pilot Study

Start date: September 13, 2023
Phase: N/A
Study type: Interventional

The goal of this pilot study is to evaluate the prospective performance of an image-based, smartphone-adaptable artificial intelligence electrocardiogram (AI-ECG) strategy to predict and detect left ventricular systolic dysfunction (LVSD) in a real-world setting.

NCT ID: NCT05629455 Completed - COVID-19 Clinical Trials

CareSuperb COVID-19 Antigen Test Usability

Start date: November 17, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the usability of the CareSuperb COVID-19 Antigen Home Test in Home Use.