There are about 15072 clinical studies being (or have been) conducted in Turkey. The country of the clinical trial is determined by the location of where the clinical research is being studied. Most studies are often held in multiple locations & countries.
Surgical hand scrubbing is the removal of transient flora and reduction of permanent flora as much as possible before any sterile gloves are worn before any surgical intervention. It is a cheap and easy method to prevent infections. Effective use of surgical hand scrubbing has an important role in preventing and reducing the transfer of health-related infections. Although many studies have been performed on surgical hand scrubbing, no standard practice has been found in the method of scrubbing and optimal duration of scrubbing time. The aim of this study is to compare evidence-based surgical hand scrubbing methods in order to prevent surgical site infections. Methods H0: There is no difference between the effectiveness of different surgical hand scrubbing methods on the bacterial flora in the hand H1: There is a difference between the effectiveness of different surgical hand scrubbing methods on the bacterial flora in the hand. Time H0: There is no difference between the effectiveness of different the duration of scrubbing time on the bacterial flora in the hand. H1: There is a difference between the effectiveness of different the duration of scrubbing time on the bacterial flora in the hand.
The World Health Organization (WHO) defines the concept of reproductive health as "not only the absence of disease or disability, but a state of complete physical, mental and social welfare in all matters related to the reproductive system, functions and processes". However, it also emphasizes that people have free will in the timing of having a satisfying and safe sexual life and using their reproductive abilities. Sexual and reproductive health and rights are essential for the health and survival of people, economic development and prosperity. In the United Nations 2030 Sustainable Development Goals, the third article named "Health and Quality Life" includes the targets covering reproductive health and sexual health. Some of these goals are; universal access to sexual and reproductive health services, creation of national education and information strategies for reproductive health, preventing sexually transmitted infections (STIs), access to information about family planning, and reducing maternal and neonatal mortality. People can lead a complete healthy and quality life only when these goals are achieved. It is observed that the knowledge of men and women about general reproductive health and the organs and functions of the female and male reproductive systems is significantly lacking. In addition to these, it has been reported that they have insufficient knowledge on other issues such as sexual health, STIs and family planning methods. There are studies showing that lack of knowledge brings about reproductive health problems in young individuals. Problems such as exposure to STIs, early pregnancy, and risky sexual behaviors arise due to lack of information. Since all these health problems can cause permanent damage, the individual's future reproductive health is also at risk. However, it is possible to come across studies showing that reproductive health education is a tool to prevent these adverse health conditions. In a study conducted with university students, even if students' basic sexual education knowledge levels were good; It has been reported that there is a positive relationship between receiving sexual education and protective sexual behaviors, knowledge, motivation and skills. At the same time, it has been reported in many studies that believing in sexual myths, which are considered as false beliefs and have no scientific value, is more common in students with high levels of knowledge. While sexual myths cause behavioral changes with believed mistakes, sexual dysfunctions, decrease in sexual satisfaction and negative attitude towards contraceptive methods can also be brought about. Considering that people who know more about sexually transmitted HIV/AIDS have a low rate of believing in myths, an important reproductive health problem such as STI should be considered to be related to myths. In this context, training on reproductive health and sexual health is important. Preparation and implementation of trainings on reproductive and sexual health by health professionals; It is important as it is known that young people have access to conflicting or incorrect information from various sources. Therefore, health professionals should be involved in these training processes. While planning the trainings, many platforms can be used, and nowadays, web-based trainings increase their importance with the introduction of the internet in all areas of our lives. The biggest advantages of web-based education are that it can be accessed anytime, anywhere and by anyone. In various studies conducted with university students, it is seen that web-based education increases the level of knowledge and is effective in behavior change. In this period when technological education emerged, many instructional design models developed were used in web-based education. Among these models, the most widely used ADDIE model. ADDIE is a model that provides a systematic and comprehensive definition and implementation of design principles. The web-based training in the research will be given based on the ADDIE Model approach. Basic elements of the instructional design process in the model; It is in the form of Analysis, Design, Development, Implementation and Evaluation. The use of a model in web-designed education ensures that the educational content is prepared according to the needs, the training steps are not skipped and systematic. In the literature review and web researches, a web-based education was not encountered in national and international publications where university students could reach the correct and scientific information about reproductive health. In this context, the investigators believe that web-based education to be provided with the ADDIE Model approach will reduce the sexual myths and risky behaviors that young people believe. This study was planned to examine the effect of web-based reproductive health education given to university students on belief in sexual myths and risky behaviors.
The study aimed to evaluate the association between the obesity grade and the age of the first acute coronary syndrome (ACS). The effect of cardiovascular (CV) risk factors and the age of first ACS in patients with severe obesity was also examined. Consecutive patients with diagnosis of first episode of ACS were prospectively enrolled in 2014 to 2024.Cardiovascular risks of patients will be determined according to clinical and laboratory evaluation and patients were categorized by their body mass indices (BMI). Independent variables that effected the age of first ACS were examined by linear regression analysis
The study is designed as a multicenter, randomized, double-blind, placebo controlled study to demonstrate the superiority of iptacopan (LNP023) at a dose of 200 mg b.i.d. compared to placebo on top of maximally tolerated ACEi or ARB on reduction of proteinuria and slowing renal disease progression in primary IgA Nephropathy patients.
The aim of this study is to determine the effect of advocacy education on social justice advocacy skills and ethical sensitivity in undergraduate nursing students.
This prospective study was planned to carried out among the patients with grade II and III (Kellgren Lawrence classification) osteoarthritis of the knee attending outpatients clinic to evaluate the effectiveness and safety of viscosupplementation with intra-articular hyaluronic acid injection.
This study aimed to compare the effects of Modified Constraint-Induced Movement Therapy (mCIMT) and Bimanual Training (BIT) based on the International Classification of Functioning, Disability, and Health, Children &Youth (ICF-CY) conceptual framework. Our assumptions were that (1) mCIMT is more effective on outcomes representing all subdomains of ICF and (2) the possible improvements in the body structure and function, activity, and participation subdomains of ICF are intimately related to each other.
Coronavirus Disease 19 (COVID-19) pandemic has become a global health problem in a short time due to high infection rate and increasing mortality. Since it is not possible to perform thorax computed tomography (CT) and transfer of patients with COVID-19 pneumonia who are followed up in intensive care, diagnosis and follow-up by lung ultrasound (LUS) is a great advantage nowadays.The investigators aimed to evaluate the correlation between thoracic CT score and LUS score and to determine its relationship with mortality. Patients who were admitted to intensive care with the diagnosis of COVID-19 pneumonia, who had an initial thorax CT examination and who underwent LUS during admission to the intensive care unit were included in the study. The demographic characteristics, clinical parameters, prognosis, thorax CT and LUS scores of the patients were recorded prospectively. The characteristics of the survived patients and the patients who died were compared.
Dual task training (DTT) have been showed that have satisfying effects on older adults. The aim of this study was to compare the effect of motor-cognitive DTT (mCdtt) and motor-motor DTT (mMdtt) on balance, fear of falling, walking functionality and muscle strength in older adults. The participants were divided into two groups; who received mCdtt (Group 1) and who received mMdtt (Group 2). The intervention program had lasted for 8 weeks.
Cow's milk allergy (CMA) is the most common Food Allergy (FA) in children, and the essential strategy in prevention is avoiding the allergens that may cause potentially life-threatening reactions. The primary developmental task of early childhood is the creation of healthy eating habits. The diagnosis of FA in this period can lead to permanent changes in the life of the child and her family. In early childhood, parents are often responsible for all aspects of FA management because children are too young to understand the complexity of avoiding allergens. Children often do not have the skills to implement FA management. Parents are advised to follow a special weaning diet, avoiding any type of cow's milk, usually at least 1 year old. However, depending on the clinical improvement, it can be recommended to continue this exclusion diet for much longer. Thus, many children have to exclude a large group of food from their diets, which is critical for their growth, development, and eating habits. This may raise mealtime behavioral anxiety in a child with a FA. Eating behavioral anxieties are also very common in healthy, typically developing children. Even 25% to 45% of normally developing children's parents report concerns about their child's nutritional and mealtime behaviors, including the destructive child behaviors (eg., refusal of foods, food selectivity, and getting off the table). In children with food allergies, monitoring long-term growth after the diet is another important issue. Growth problems were reported in 21% of children with FA diagnosed with malnutrition. Most studies focused on the effect of changes in eating behavior on growth during an elimination diet or in short term intervals. Its long-term effects have only been analyzed in a few studies. We aimed to investigate the eating behaviors, nutritional status, and growth of young children (ages of 2 to 6) who had a strict diet due to CMA in early childhood (ages of 0-2).