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NCT ID: NCT05676996 Recruiting - Attachment Disorder Clinical Trials

Investigation of the Effect of Attachment-Based Support Given in the Perinatal Period

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

It is important that effective intervention programs are developed and implemented in our country by identifying risk factors in the early period. In this aspect, the work is unique. Unlike the studies in the literature, it is a unique study in terms of determining the risky population that needs to be questioned and strengthened during the prenatal attachment of expectant mothers during pregnancy, and creating a program where mothers can receive uninterrupted support for 24 hours.

NCT ID: NCT05676983 Recruiting - Cerebral Palsy Clinical Trials

Investigation of the Effects of Balance Discs With Different Surfaces Used in Balance Education in Children With Cerebral Palsy on Proprioceptive Sense and Balance.

Start date: December 5, 2022
Phase: N/A
Study type: Interventional

This is a non-invasive prospective study investigating the effects of balance discs with different surfaces used in balance education in children with cerebral palsy on proprioceptive sense and balance.

NCT ID: NCT05675891 Recruiting - Nutrition Clinical Trials

Oral Feeding Ability of Preterm Infants With Breastfeeding Support System

Start date: July 20, 2022
Phase: N/A
Study type: Interventional

This research 34.-36. is carried out as a randomized controlled experimental design in order to evaluate the effectiveness of the supplemental feeding system to improve the early feeding skills of preterm infants receiving care in the neonatal intensive care unit at the gestational week.The universe of this research will consist of preterm infants hospitalized in the neonatal intensive care of Sanlıurfa Training and Research Hospital between July 2022 and April 2023. The sample size in the study was "H00: There is no difference between preterm infants with supplemental feeding system and preterm infants fed with bottle in terms of early feeding skills." According to the hypothesis G*Power Version 3.1.9.2 (Franz Foul, Universitat Kiel, Germany) was calculated in the program. In order to determine the difference between the groups, the number of groups is 2; number of repeated measurements 3; correlation between repeated measurements 0.5; Cohen* effect size 0.25; The statistical power was determined as a sample size of 44 preterm infants, 22 of whom were fed with supplemental feeding system and 22 of whom were fed with bottle, with 95% and type 1 error of 5%. and infants assigned to groups by randomization method. Randomization in the study determined by entering the total number of cases through the program http://www.randomizer.org. Through this program, the infants forming the sample group randomly distributed to two groups and randomization made.

NCT ID: NCT05673707 Recruiting - Clinical trials for Airway Complication of Anesthesia

The Effect of Thyromental Height and Other Difficult Airway Evaluation Parameters

Start date: July 1, 2022
Phase:
Study type: Observational

Many changes occur in the body with age. There are difficulties in endotracheal intubation and the placement of supraglottic airway devices (LMA) in elderly patients due to changes in the tooth and facial structure, and a decrease in temporomandibular joint and neck movements. In the literature, there are studies on the relationship between thyromental height measurement and endotracheal intubation difficulty, but there is no study on the relationship between thyromental height measurement and laryngeal mask placement difficulty.

NCT ID: NCT05673642 Recruiting - Low Back Pain Clinical Trials

Effect of Myofascial Release Technique Applied to in Patients With Temporomandibular Dysfunction

Start date: May 10, 2021
Phase: N/A
Study type: Interventional

We aim to compare the effectiveness of MFR and exercise therapy on mobility and function by investigating the effectiveness of the Myofascial Release Technique (MFR), which we will apply to the muscles we choose related to the facial system connection in participants with temporomandibular dysfunction (TMD) and low back pain.

NCT ID: NCT05672199 Recruiting - Ulcerative Colitis Clinical Trials

Long-term Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerative Colitis

Start date: April 28, 2023
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the long-term safety and tolerability of efavaleukin alfa in participants with moderate to severe ulcerative colitis (UC).

NCT ID: NCT05671510 Recruiting - Clinical trials for Non Small Cell Lung Cancer

ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors

PRESERVE-003
Start date: June 28, 2023
Phase: Phase 3
Study type: Interventional

The goal of this Phase 3 clinical trial is study the safety and efficacy of the nextgen anti-CTLA-4 antibody, gotistobart (ONC-392/BNT316), in patients with metastatic non-small cell lung cancer who have disease progressed on anti-PD-1/PD-L1 antibody based therapy. The study will test whether gotistobart, in comparison with chemotherapy agent docetaxel, could prolong the life for NSCLC patients. Patients will be randomized to be treated with either gotistobart or docetaxel, IV infusion, once every 21 days, for up to 17 cycles in approximately one year.

NCT ID: NCT05671484 Recruiting - Clinical trials for Surgical Procedure, Unspecified

TFPB vs QLB III in Infra-umbilical Pediatric Surgeries

Start date: January 5, 2022
Phase: N/A
Study type: Interventional

Regional anesthetic techniques; they reduce postoperative morbidity, provide early mobilization and provide great advantages by significantly reducing the need for narcotic analgesics. Regional anesthetic techniques are widely used in our clinic for postoperative analgesia, especially in infants and children. In patients undergoing lower abdominal surgery, postoperative analgesia is usually provided by systemic opioids and neuraxial methods. Complications such as sedation, respiratory depression, itching, nausea, vomiting and possible paraplegia or bleeding of neuraxial methods due to the use of opioids seem to be the biggest disadvantages of these two methods. Transversalis fascial plane (TFP) block is a regional anesthesia technique that provides intraoperative and postoperative analgesia as an alternative to caudal and epidural analgesia, especially in children. Transversalis fascial plane (TFP) block was first described in 2009. TFP block has been shown to be effective as an alternative to epidural analgesia and as part of a multimodal postoperative analgesic approach in lower abdominal and pelvic surgeries in children. Quadratus lumborum block (QLB) is a widely used regional anesthesia technique. It is used in pediatric patients to reduce postoperative pain in supraumbilical or infraumbilical surgeries. As a common result of all approaches, the main effect in quadratus lumborum block is anesthesia of the lateral cutaneous branches. In our center, the investigators have been using both methods, alone or in combination, routinely for a long time, and the investigators aim to compare the two methods in this study. This study consists of comparing two domain blocks known as part of multimodal analgesia.

NCT ID: NCT05671211 Recruiting - Stroke Clinical Trials

Effects Of Task-Oriented Training In Individuals With Stroke

Start date: January 10, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effects of task-oriented training on balance,functional mobility,walking, activities of daily living and quality of life in individuals with stroke.

NCT ID: NCT05670795 Recruiting - Clinical trials for Infertility Unexplained

Comparison of Recombinant Follicle Stimulating Hormone and the Combination of Recombinant Follicle Stimulating Hormone With Clomiphene Citrate in Stimulated Intrauterine Insemination Cycles

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

The aim of study is to evaluate the results of two different protocols for ovulation induction during IUI cycles. All patients undergo IUI cycles are randomly divided in to two groups. the first group is recombinant follicle stimulating hormone and the second group is the combination of recombinant follicle stimulating hormone with clomiphene citrate.