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NCT ID: NCT02947438 Completed - Renal Anemia Clinical Trials

Biosimilar Erythropoietin in Anaemia Treatment (Maintenance Phase Study)

BEAT_002
Start date: December 2015
Phase: Phase 3
Study type: Interventional

This study is aimed to comprehensively establish the bio-similarity/bioequivalence in EPIAO® and EPREX® in terms of 52-week comparisons in efficacy, safety and immunogenicity. The targeted population is anaemia patients with end-stage chronic renal disease who previously received epoetin treatment and on haemodialysis.

NCT ID: NCT02946463 Completed - Clinical trials for Paroxysmal Nocturnal Hemoglobinuria (PNH)

ALXN1210 (Ravulizumab) Versus Eculizumab in Complement Inhibitor Treatment-Naïve Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Start date: December 12, 2016
Phase: Phase 3
Study type: Interventional

The primary purpose of this study was to assess the noninferiority of ravulizumab compared to eculizumab in adult participants with PNH who had never been treated with a complement inhibitor (treatment-naïve).

NCT ID: NCT02945358 Completed - ICU Stay Clinical Trials

Assessment of OHIR Score to Predict a Prolonged Intensive Care Unit Stay

Start date: September 2016
Phase: N/A
Study type: Observational

A prolonged stay in intensive care unit (ICU) after cardiac surgery with cardiopulmonary bypass increases not only cost of patient care but also morbidity and mortality of patients. The ability to predict which patient has the tendency to have a prolonged ICU stay would help in patient and resource management of the hospital. There are many predictive models aiming at identifying patient at risk of prolonged ICU stay after cardiac surgery with cardiopulmonary bypass but almost all involve the preoperative assessment for proper resource management with one model, Open-Heart Intraoperative Risk (OHIR) Scoring concerning intraoperative manipulatable risk factors to improve anesthetic care and patient outcome. The OHIR model comprises 6 risk factors, 5 of which can be managed intraoperatively, with total score of 7 and a score of ≥ 3 indicating a likely prolonged ICU stay. The objective of this study was to re-validate the performance of OHIR score in the recent context.

NCT ID: NCT02944981 Completed - Clinical trials for Postoperative Nausea and Vomiting

Gabapentin to Reduce Postoperative Nausea and Vomiting

Start date: August 2016
Phase: Phase 4
Study type: Interventional

The intrathecal administration of morphine is gaining popularity. It is easy to do and can reduce the pain after surgery up to 24 hours. However, it causes postoperative nausea and vomiting more than other methods providing postoperative analgesia. Patients suffering from these side effects have to spend a longer period of time recovering in the hospital with high cost of medical treatment.

NCT ID: NCT02944942 Completed - Clinical trials for Postoperative Nausea and Vomiting

Risk Factors for Postoperative Nausea/Vomiting

Start date: September 2016
Phase: N/A
Study type: Observational

General anesthetic technique plays a key role in most surgical procedures. This technique has some complications especially postoperative nausea/vomiting (PONV). This complication can lead to serious problems. Department of Anesthesiology has developed and implemented a PONV prophylaxis guideline for high risk PONV patients but PONV still remains.

NCT ID: NCT02944305 Completed - Clinical trials for Difficult Intubation

A Predictive Model for Difficult Intubation

Start date: September 2016
Phase: N/A
Study type: Observational

Failure in airway management is one of the most common anesthesia-related morbidity and mortality. Each individual airway assessment has limitation to predict difficult intubation.

NCT ID: NCT02941926 Completed - Breast Cancer Clinical Trials

Study to Assess the Safety and Efficacy of Ribociclib (LEE011) in Combination With Letrozole for the Treatment of Men and Pre/Postmenopausal Women With HR+ HER2- aBC

COMPLEEMENT-1
Start date: November 30, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to collect additional safety and efficacy data for the combination of ribociclib + letrozole in men and pre/postmenopausal women with HR+HER2- advanced breast cancer and no prior hormonal treatment for advanced disease..

NCT ID: NCT02939482 Completed - Spinal Stenosis Clinical Trials

A Study Comparison of Clinical Outcome After Different Rate of Infusion in Caudal Epidural Steroid Injection

Start date: October 1, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effects of different rates of Caudal Epidural Steroid Injection (CESI) on clinical outcomes of the patients.

NCT ID: NCT02931747 Completed - Healthy Clinical Trials

Effect of Bacopa Monnieri on Working Memory and Cognitive Processing in Student

Start date: July 2016
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the effect of Bacopa Monnieri on working memory and cognitive processing in student.

NCT ID: NCT02927613 Completed - Clinical trials for Prolonged Mechanical Ventilation

Patient Characteristics, Feasibility, and Outcomes of a Home Mechanical Ventilation Program in a Developing Country

Start date: November 2014
Phase: N/A
Study type: Observational

This study aims to describe the patient characteristics, feasibility, and outcomes of an home mechanical ventilation (HMV) program at a university hospital in Thailand.