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NCT ID: NCT00354341 Completed - Anemia Clinical Trials

(ACORD Study) - A Study of NeoRecormon (Epoetin Beta) in Patients With Early Diabetic Nephropathy

Start date: n/a
Phase: Phase 3
Study type: Interventional

This study will assess the effect of anemia correction with NeoRecormon on cardiac structure and function in patients with early diabetic nephropathy. The anticipated time on study treatment is 1-2 years and the target sample size is 100-500 individuals.

NCT ID: NCT00351611 Completed - Epilepsies, Partial Clinical Trials

Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo

Start date: July 26, 2006
Phase: Phase 4
Study type: Interventional

Patients with partial seizures currently taking 1-3 antiepileptic medications will have a 50:50 chance to receive Lyrica 300 mg per day or placebo (no active ingredients) added on to their current medications for 3 months. Neither the study doctor nor the patient will know the medication assignment. Vision testing will be performed prior to receiving the study treatment and at the end of the study to see if there are any changes.

NCT ID: NCT00351468 Completed - Clinical trials for Purpura, Thrombocytopaenic, Idiopathic

EXTEND (Eltrombopag Extended Dosing Study)

EXTEND
Start date: June 2006
Phase: Phase 3
Study type: Interventional

An open-label, dose-adjustment, extension study to evaluate the safety and efficacy of eltrombopag for the treatment of subjects with idiopathic thrombocytopenic purpura (ITP) who have previously been enrolled in an eltrombopag trial. This study will allow adjustment of the eltrombopag dose to achieve an individualized dose and schedule for each subject. In addition, the ability to reduce the dose of concomitant ITP medications in the presence of eltrombopag, while maintaining platelet counts = 50,000/microL will be investigated.

NCT ID: NCT00348426 Completed - Botulism Clinical Trials

Botulism Outbreak in Thailand (Episode II)

Start date: June 2006
Phase: Phase 4
Study type: Observational

A second botulism outbreak in Northern Thailand was reported in 2006. 192 people were exposed to raw meat and the gut of deer, 83 suffered from diarrhea. Of these 5 developed respiratory failure, 1 impending respiratory failure. We analysed the clinical findings and electrophysiologic findings in this second episode of large botulism outbreak in northern Thailand.

NCT ID: NCT00347919 Completed - Neoplasms, Breast Clinical Trials

Pazopanib Plus Lapatinib Compared To Lapatinib Alone In Subjects With Advanced Or Metastatic Breast Cancer

Start date: July 2006
Phase: Phase 2
Study type: Interventional

This study is being conducted to compare the efficacy and safety of pazopanib in combination with lapatinib with that of lapatinib alone in subjects with locally advanced or metastatic breast cancer whose tumors overexpress the ErbB2 protein.

NCT ID: NCT00347490 Completed - Hemodialysis Clinical Trials

HENOX: Enoxaparine in Hemodialysis

Start date: May 2006
Phase: Phase 4
Study type: Interventional

Primary objective: To assess clinical efficacy of single bolus anticoagulation with Enoxaparin in chronic hemodialysis Secondary objective: To assess safety and tolerability by the number of spontaneously reported adverse events by patients

NCT ID: NCT00337181 Completed - HIV-1 Clinical Trials

Follow up of Thai Adult Volunteers With Breakthrough HIV Infection After Participation in a Preventive HIV Vaccine Trial

Start date: May 2006
Phase:
Study type: Observational

This protocol will study the clinical course of HIV-infection among volunteers who have received either a placebo injection or the experimental vaccine combination of ALVAC-HIV and AIDSVAX B/E prior to HIV-1 infection in reference to study NCT00223080 RV144. The study will assess whether those who received the experimental vaccine combination have a slower progression of HIV disease compared to those who received the placebo injection.

NCT ID: NCT00335374 Completed - Clinical trials for Early Stage Parkinson's Disease

An Open Label SLV308 Safety Extension to Study S308.3.003 in Early PD Patients

Start date: August 2007
Phase: Phase 3
Study type: Interventional

This is a multicenter, 6 months open label safety extension study for all patients who are willing and eligible to continue from the pivotal, double-blind S308.3.003 trial

NCT ID: NCT00335166 Completed - Clinical trials for Early Stage Parkinson Disease

SLV 308 and Pramipexole for Treatment of Patients With Early Parkinson Disease

Start date: November 2006
Phase: Phase 3
Study type: Interventional

This is a multicenter, randomized, double blind, parallel group study of 6 months' treatment with SLV308 as monotherapy in patients with early stage PD. An open label safety extension to this study is planned as a separate protocol for patients who are willing and eligible to participate.

NCT ID: NCT00335153 Completed - Clinical trials for Advanced Parkinson's Disease

Levodopa-Carbidopa Intestinal Gel Open-Label Study in Advanced Parkinson's Disease

Start date: January 2008
Phase: Phase 3
Study type: Interventional

The primary objective of this study will be to provide further evidence of the long-term safety and tolerability of levodopa-carbidopa intestinal gel (Duodopa®) over 12-months in participants with advanced Parkinson's disease (PD) and severe motor fluctuations.