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NCT ID: NCT00389155 Completed - Bladder Cancer Clinical Trials

First-Line Treatment of Advanced Bladder Cancer Randomized vs. Gemcitabine ± Vinflunine in Patients Ineligible to Receive Cisplatin-Based Therapy

Start date: January 2007
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to test an investigational drug, vinflunine (BMS-710485), in combination with gemcitabine in patients with Transitional Cell Carcinoma who cannot be treated with cisplatin. This study will help to determine whether vinflunine in combination with gemcitabine will extend the time period until further growth of the tumor more than gemcitabine alone.

NCT ID: NCT00388674 Completed - Chronic Hepatitis B Clinical Trials

Study of Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection

Start date: December 18, 2006
Phase:
Study type: Observational

The purpose of this study is to prospectively assess the long-term outcomes (benefits and risks) associated with entecavir (ETV) therapy as compared to other antivirals approved for the treatment of chronic HBV infection. For the China substudy, patients randomized to entecavir will have safety and efficacy assessments performed during the first year of the study.

NCT ID: NCT00386646 Completed - Dry Eye Syndromes Clinical Trials

Comparative Study of 0.5% Carboxymethylcellulose With 0.005% Stabilized Oxychlorocomplex (PURITEā„¢) Versus 0.5% Carboxymethylcellulose in the Treatment of Dry Eye

Start date: February 2004
Phase: Phase 4
Study type: Interventional

To compare if 0.5% carboxymethylcellulose with 0.005% SOC (Stabilized oxychloro complex) have the same effectiveness and safety as 0.5% carboxymethylcellulose on dry eye patients.

NCT ID: NCT00386438 Completed - Cataract Clinical Trials

Efficacy of Honan Balloon in Intraocular Pressure Reduction Before Phacoemulsification

Start date: December 2005
Phase: Phase 4
Study type: Interventional

-Does Honan balloon reduce intraocular pressure preoperatively?

NCT ID: NCT00386230 Completed - HIV Infections Clinical Trials

Shortened Zidovudine Regimens to Prevent Mother-to-Child Transmission of HIV Type 1

Start date: June 1997
Phase: Phase 3
Study type: Interventional

The purpose of the study was to test the equivalence of a short zidovudine (ZDV) regimen as compared to a longer, ACTG-076-like, ZDV regimen in reducing the risk of mother-to-child transmission of HIV: and to assess and compare the safety and tolerance of the long and shortened ZDV regimens.

NCT ID: NCT00384670 Completed - Dengue Fever Clinical Trials

A Phase I/II Trial of a Tetravalent Live Attenuated Dengue Vaccine in Flavivirus Antibody Naïve Children

Start date: August 2003
Phase: Phase 1/Phase 2
Study type: Interventional

To assess the safety, reactogenicity and immunogenicity of two doses of the dengue vaccine in Flavi-virus antibody-naive children between 6 and 9 years of age.

NCT ID: NCT00384176 Completed - Colorectal Cancer Clinical Trials

First Line Metastatic Colorectal Cancer Therapy in Combination With FOLFOX

HORIZON III
Start date: August 30, 2006
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to see if Cediranib in combination with FOLFOX is effective in treating metastatic colorectal cancer and to see how it compares with Avastin (Bevacizumab) in combination with FOLFOX.

NCT ID: NCT00371813 Completed - Smoking Cessation Clinical Trials

An Investigation of Effectiveness and Safety of Varenicline Tartrate in Helping People Quit Smoking

Start date: September 2006
Phase: Phase 3
Study type: Interventional

To investigate safety and efficacy of varenicline tartrate in helping people quit smoking

NCT ID: NCT00370682 Completed - Dengue Clinical Trials

A Phase II Trial of a Live Attenuated Virus Tetravalent Dengue Vaccine in Healthy Adults in Thailand

Start date: April 2007
Phase: Phase 2
Study type: Interventional

This descriptive study will evaluate the safety and immunogenicity of different formulations of the WRAIR dengue vaccine compared to a placebo.

NCT ID: NCT00368537 Completed - Clinical trials for Skin Diseases, Bacterial

Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections

Start date: September 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the safety and efficacy of the antibiotic tigecycline with other antibiotics, ampicillin-sulbactam, and amoxicillin-clavulanate in the treatment of a complicated skin and/or skin structure infection (cSSSI).