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NCT ID: NCT01603641 Completed - Cerebral Palsy Clinical Trials

BOTOX® Open-Label Treatment in Pediatric Lower Limb Spasticity

Start date: November 5, 2012
Phase: Phase 3
Study type: Interventional

This study will evaluate the long-term safety of BOTOX® (botulinum toxin Type A) for the treatment of pediatric lower limb spasticity.

NCT ID: NCT01603628 Completed - Cerebral Palsy Clinical Trials

BOTOX® Treatment in Pediatric Lower Limb Spasticity

Start date: September 11, 2012
Phase: Phase 3
Study type: Interventional

This study will evaluate the safety and efficacy of BOTOX® (botulinum toxin Type A) in pediatric patients with lower limb spasticity.

NCT ID: NCT01603615 Completed - Stroke Clinical Trials

BOTOX® Open-Label Treatment in Pediatric Upper Limb Spasticity

Start date: October 30, 2012
Phase: Phase 3
Study type: Interventional

This study will evaluate the long-term safety of BOTOX® (botulinum toxin Type A) for the treatment of pediatric upper limb spasticity.

NCT ID: NCT01603602 Completed - Stroke Clinical Trials

BOTOX® Treatment in Pediatric Upper Limb Spasticity

Start date: July 12, 2012
Phase: Phase 3
Study type: Interventional

This study will evaluate the safety and efficacy of BOTOX® (botulinum toxin Type A) in pediatric patients with upper limb spasticity.

NCT ID: NCT01602952 Completed - Leukemia Clinical Trials

Philadelphia Chromosome Positive CML Patients Without Optimal Response or Tolerance to Bcr-Abl TKI

Start date: July 2008
Phase: Phase 1/Phase 2
Study type: Interventional

A Phase I/II multicenter study of IY5511HCl in Philadelphia chromosome positive chronic myeloid leukemia patients without optimal response or tolerance to Bcr-Abl tyrosine kinase inhibitors (Imatinib and/ or Dasatinib, Nilotinib) In this study, The efficacy and safety of CML patients who are resistant or intolerable to imatinib in the Chronic and Accelerated phases. Phase 1 1. To investigate the Maximum Tolerated Dose (MTD) and the Dose Limiting Toxicity (DLT) of oral Radotinib HCl bid (twice daily) in the Philadelphia chromosome-positive CML subjects who are resistant, suboptimal responsive, or intolerant to imatinib OR resistant or intolerant to at least one second-generation targeted anticancer agent while being resistant, suboptimal responsive, or intolerant to imatinib simultaneously. Phase 2 1. To investigate safety of oral Radotinib HCl in CML patients who are resistant or intolerable to imatinib in the chronic and accelerated phases. 2. To evaluate hematologic and cytogenetic efficacy of oral Radotinib HCl in CML patients who are resistant or intolerable to imatinib in the chronic and accelerated phases.

NCT ID: NCT01601613 Completed - Clinical trials for Acquired Bleeding Disorder

Activated Recombinant Human Factor VII in Patients With Dengue Haemorrhagic Fever

Start date: July 2001
Phase: Phase 2
Study type: Interventional

This trial is conducted in Asia. The aim of this is to investigate the efficacy and safety of activated recombinant human factor VII (rFVIIa) in achieving haemostasis in patients with Dengue haemorrhagic fever (DHF).

NCT ID: NCT01599351 Completed - Clinical trials for Exposure to Ionizing Radiation

Radiation Exposure During Endoscopic Retrograde Cholangiopancreatography Between Prone and Left Lateral Decubitus

Start date: July 2009
Phase: Phase 4
Study type: Interventional

The objective of this study is to evaluate the radiation dose to patient at two positions (prone and left lateral) and to medical staff during Endoscopic retrograde cholangiopancreatography (ERCP) procedure using dose area product (DAP) meter and thermoluminescent dosimeter (TLD). Data were recorded on 20 patients at prone position and 20 patients at left lateral position.

NCT ID: NCT01598012 Completed - Clinical trials for Primary Dysmenorrhea

The Efficacy of Ayurved Siriraj Prasaplai for Treatment Primary Dysmenorrhea

Start date: December 2011
Phase: Phase 4
Study type: Interventional

Ayurved Siriraj Prasaplai is a Thai traditional herbal drug for pain treatment. Mostly it was used for antipain during menstruation or dysmenorrhea. This drug has been described by alternative medical doctor for treatment of primary dysmenorrhea for more than 10 years and showed clinical satisfied response. From review about this agent, it does not have clinical trial to prove its efficacy. So the author produce this research to study in efficacy of Ayurved Siriraj Prasaplai.

NCT ID: NCT01597973 Completed - Pneumonia Clinical Trials

Trial for the Treatment of Extensively Drug-Resistant Gram-negative Bacilli (OVERCOME)

Start date: October 6, 2012
Phase: Phase 3
Study type: Interventional

Approximately 444 subjects who are greater than or equal to 18 to 95 years of age, are non-pregnant, and are in the inpatient setting of one of the study sites will be evaluated to treatment efficacy. Analysis will include subjects with bloodstream infection (BSI) or pneumonia due to at least one of the following gram-negative bacilli organisms: Acinetobacter baumannii, Klebsiella spp, Escherichia coli, Enterobacter spp. and/or Pseudomonas aeruginosa that demonstrates in vitro non-susceptibility defined as extensively drug-resistant Gram-negative bacilli (XDR-GNB) which includes XDR-AB, XDR-PA and CRE. If a subject has both BSI and pneumonia at the time of study enrollment, they will be included as a subject with pneumonia. Objectives: Primary: •Determine whether the treatment regimen of Colistimethate sodium (colistin) combined with a carbapenem (imipenem or meropenem) is associated with a decreased risk for mortality compared to colistin alone for subjects with bloodstream infection (BSI) and/or pneumonia due to XDR-GNB. Secondary: •Determine what treatment regimen (colistin monotherapy or colistin combined with a carbapenem (imipenem or meropenem) is more likely to reduce the emergence of colistin resistance among XDR-GNB isolates during therapy.

NCT ID: NCT01597765 Completed - Thalassemia Clinical Trials

Effect of Antioxidant Cocktail in Beta-thalassemia/Hb E Patients

Start date: June 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the efficacy of antioxidant cocktails on the alleviation of oxidative stress and iron overload in beta-thalassemia/Hb E patients.