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NCT ID: NCT00124891 Terminated - Arrhythmias Clinical Trials

Study Evaluating GAP-486 in Non-sustained Ventricular Tachycardia

Start date: June 1, 2005
Phase: Phase 2
Study type: Interventional

To determine whether the administration of test article will decrease the occurrence of ventricular arrhythmias in patients who have acute coronary syndrome (unstable angina, ST segment elevated myocardial infarction or myocardial infarction without ST elevation).

NCT ID: NCT00123487 Completed - Clinical trials for Leukemia, Lymphoblastic, Acute, Philadelphia-Positive

Advanced Chronic Myelogenous Leukemia (CML) - Follow On: Study of BMS-354825 in Subjects With CML

Start date: June 2005
Phase: Phase 3
Study type: Interventional

This is a phase III study of BMS-354825 in subjects with chronic myelogenous leukemia in accelerated phase, or in myeloid or lymphoid blast phase or with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia who are resistant or intolerant to imatinib mesylate (Gleevec).

NCT ID: NCT00123474 Completed - Clinical trials for Myeloid Leukemia, Chronic, Chronic-Phase

Chronic Myelogenous Leukemia (CML) - Follow on: Study of BMS-354825 in Subjects With CML

Start date: July 2005
Phase: Phase 3
Study type: Interventional

This is a phase III study of BMS-354825 in subjects with chronic phase Philadelphia chromosome or BCR-ABL positive chronic myelogenous leukemia, who are resistant or intolerant to imatinib mesylate (Gleevec).

NCT ID: NCT00122824 Completed - Anxiety Disorders Clinical Trials

Duloxetine Compared With Placebo in Patients With Generalized Anxiety Disorder

Start date: June 2004
Phase: Phase 3
Study type: Interventional

This is a clinical trial assessing duloxetine compared with placebo in patients who have generalized anxiety disorder.

NCT ID: NCT00122460 Completed - Clinical trials for Head and Neck Cancer

Cetuximab (Erbitux) in Combination With Cisplatin or Carboplatin and 5-Fluorouracil in the First Line Treatment of Subjects With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck (EXTREME)

Start date: December 2004
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to investigate the efficacy of cetuximab in combination with chemotherapy in comparison to chemotherapy alone in patients with recurrent or metastatic head and neck cancer. Overall survival will be taken as the primary measure of efficacy.

NCT ID: NCT00122330 Completed - Clinical trials for Hemoglobinuria, Paroxysmal

Study Using Eculizumab in Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients

Start date: October 2004
Phase: Phase 3
Study type: Interventional

The primary objective is to evaluate the safety and efficacy of eculizumab in transfusion dependent patients with hemolytic PNH.

NCT ID: NCT00122317 Completed - Clinical trials for Paroxysmal Hemoglobinuria, Nocturnal

Extension Study of Eculizumab in Patients With Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH)

Start date: May 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the long-term safety of eculizumab in patients with transfusion dependent hemolytic PNH.

NCT ID: NCT00122304 Completed - Clinical trials for Hemoglobinuria, Paroxysmal

Study of Safety in Hemolytic Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Treated With Eculizumab

Start date: December 2004
Phase: Phase 3
Study type: Interventional

The primary objective is to evaluate the safety of eculizumab in patients with transfusion-dependent hemolytic PNH

NCT ID: NCT00121901 Completed - Pancreatitis Clinical Trials

Does Glyceryl Nitrate Prevent Post-Endoscopic Retrograde Cholangiopancreaticography (ERCP) Pancreatitis?

Start date: October 2004
Phase: Phase 3
Study type: Interventional

Post-ERCP pancreatitis can be a serious complication to ERCP. Two studies have shown a promising preventive effect of glyceryl nitrate. This study should provide a final answer to the clinical question: Does glyceryl nitrate prevent post-ERCP pancreatitis? The study is a prospective, randomized, double blind, placebo-controlled multicenter trial. The investigators intend to include 1600 patients from Norway, Sweden, Denmark, and France. The patients will receive either placebo or a glyceryl nitrate patch (15 mg/24 hours). Follow-up will occur after 7 days. The primary outcome measure will be post-ERCP pancreatitis, and secondary outcome measures will be mild, moderate and severe pancreatitis; post procedure pancreatitis-related mortality; and adverse events.

NCT ID: NCT00120900 Completed - Clinical trials for Osteoarthritis, Knee

Evaluation of GW406381 in Treating Adults With Osteoarthritis Of The Knee

Start date: May 2005
Phase: Phase 3
Study type: Interventional

This study was designed to evaluate the effectiveness of GW406381 (a COX-2 inhibitor) in treating the signs and symptoms of osteoarthritis of the knee.