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NCT ID: NCT00185380 Completed - Contraception Clinical Trials

Dose-finding Study for the Ultralow-dose Levonorgestrel Intrauterine Contraceptive System (LCS)

Start date: April 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate if drug doses lower than the one released from Mirena® would be as effective for contraception as Mirena®. Subjects participating in the study will be randomly assigned to be inserted with any of the three different intrauterine systems (IUSs). The IUSs are nearly alike except that the amount of hormone released from them is different.

NCT ID: NCT00185341 Completed - Endometriosis Clinical Trials

Study to Investigate the Efficacy of a Non-hormonal Drug Against Endometriosis Associated Pelvic Pain

Start date: February 2005
Phase: Phase 2
Study type: Interventional

This study was designed as a proof-of-concept trial to evaluate safety, tolerability, and the efficacy of 1800 mg (ZK 811752 600 mg given orally three times daily) over 12 weeks for the treatment of endometriosis associated pelvic pain (EAPP) in comparison to placebo.

NCT ID: NCT00185250 Completed - Heart Diseases Clinical Trials

Betaferon/ Betaseron (Interferon Beta-1b) in Patients With Chronic Viral Cardiomyopathy

Start date: December 2002
Phase: Phase 2
Study type: Interventional

Chronic viral cardiomyopathy is a disease where the cardiac muscle is attacked by a virus and this may result in a reduction in the output of the heart (pump function) thereby causing complaints such as chest pain, shortness of breath and palpitations. Betaferon (interferon beta-1b) is marketed for the treatment of Multiple Sclerosis already, but until now, it has not been proven whether it is also effective in patients with chronic viral myocardial disease. This study will be conducted to examine the efficacy and safety of Betaferon in patients with this disease. The aim of the treatment is to eliminate the virus from the heart so that the heart function and clinical status can gradually improve.

NCT ID: NCT00185211 Completed - Multiple Sclerosis Clinical Trials

BENEFIT Study (Betaferon® / Betaseron® in Newly Emerging Multiple Sclerosis for Initial Treatment) and BENEFIT Follow-up Study

Start date: August 2002
Phase: Phase 3
Study type: Interventional

This study will primarily compare the long-term effects of an early and continued treatment with Betaferon/Betaseron (patients who were treated with active medication during the double-blind BENEFIT study) to treatment initiated either after Clinically Definite Multiple Sclerosis (CDMS) has been diagnosed or after two years (those patients who were treated with placebo during the double-blind BENEFIT study). Analyses are based on the integrated data of the initial BENEFIT study and this follow-up study.

NCT ID: NCT00185198 Completed - Male Clinical Trials

Efficacy and Safety of Testogel® in Men With Partial Androgen Deficiency of Aging Males (PADAM)

Start date: September 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the effect of a testosterone replacement therapy called Testogel in men with PADAM. The effects on body composition (lean, fat and bone) and other symptoms of PADAM and safety will be studied.

NCT ID: NCT00184795 Completed - Menopause Clinical Trials

Bleed Free Treatment of Menopausal Symptoms With New Ultra Low Dose Hormonal Combinations

CHOICE
Start date: May 28, 2004
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe. Postmenopausal women with moderate to severe hot flashes have been recruited into the trial. The earliest effect of ultra low dose HRT (hormone replacement therapy) on frequency and severity of menopausal symptoms, bleeding patterns and safety of different hormonal combinations will be evaluated and compared to placebo over the six month treatment period.

NCT ID: NCT00184756 Completed - Clinical trials for Small for Gestational Age

Efficacy on Height in SGA Children Treated With Growth Hormone

Start date: November 2002
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe and Middle East. Growth hormone in SGA Children This trial compares a treated group of patients with an untreated group of patients.

NCT ID: NCT00184678 Completed - Clinical trials for Adult Growth Hormone Deficiency

Effect of Growth Hormone on Bone Mineral Density in Young Adults With Child-hood Onset Growth Hormone Deficiency

Start date: February 2002
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe. Growth Hormone in young adults with growth hormone deficiency in childhood. This trial compares a treated group of patients with an untreated group of patients.

NCT ID: NCT00184652 Completed - Clinical trials for Chronic Kidney Disease

Growth Hormone Treatment in Adult Patients With Chronic Kidney Disease

Start date: April 2003
Phase: Phase 2
Study type: Interventional

This trial is conducted in Asia, Europe, and Middle East. Adult patients with chronic kidney disease are treated with growth hormone to assess effect on nutritional status.

NCT ID: NCT00182819 Completed - Clinical trials for Brain and Central Nervous System Tumors

Radiation Therapy or Temozolomide in Treating Patients With Gliomas

Start date: July 2005
Phase: Phase 3
Study type: Interventional

RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether radiation therapy is more effective than temozolomide in treating gliomas. PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works compared to temozolomide in treating patients with gliomas.