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NCT ID: NCT00207740 Completed - Asthma Clinical Trials

A Study of Safety and Efficacy of CNTO 148 in Patients With Severe Persistent Asthma

Start date: August 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effectiveness and safety of CNTO 148 (golimumab) in patients with severe persistent asthma.

NCT ID: NCT00206310 Completed - Heart Failure Clinical Trials

Crestor Versus Placebo in Subjects With Heart Failure

Start date: September 2003
Phase: Phase 3
Study type: Interventional

The purpose of the study is to investigate if rosuvastatin, added on top of all other medicines prescribed to subjects with symptomatic systolic heart failure, reduces the combined endpoint of cardiovascular death or non-fatal myocardial infarction or non-fatal stroke (time to first event)

NCT ID: NCT00206284 Completed - Clinical trials for GERD Without Erosive Esophagitis

A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients Without Erosive Esophagitis.

Start date: May 2004
Phase: Phase 2
Study type: Interventional

The primary objective is to compare the efficacy between three doses of AZD0865 (25, 50 and 75 mg). The secondary objectives are to compare the efficacy between the three doses of AZD0865 and esomeprazole 20 mg and to evaluate the safety and tolerability of AZD0865.

NCT ID: NCT00206245 Completed - Clinical trials for GERD With Erosive Esophagitis

A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients With Erosive Esophagitis.

Start date: May 2004
Phase: Phase 2
Study type: Interventional

The primary objective is to compare the efficacy between three doses of AZD0865 (25, 50 and 75 mg). The secondary objectives are to compare the efficacy between the three doses of AZD0865 and esomeprazole 40 mg and to evaluate the safety and tolerability of AZD0865.

NCT ID: NCT00206219 Completed - Clinical trials for Squamous Cell Carcinoma of the Head and Neck

Head and Neck Phase III Iressa Versus Methotrexate Refractory: Iressa Versus Methotrexate (IMEX)

Start date: November 2003
Phase: Phase 3
Study type: Interventional

This study is to compare ZD1839 (250mg and 500mg) versus methotrexate in head and neck cancer in terms of overall survival.

NCT ID: NCT00206089 Terminated - Thromboembolism Clinical Trials

Melagatran/Ximelagatran Versus Enoxaparin for the Prevention of Venous Thromboembolic Events

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Start date: September 2005
Phase: Phase 3
Study type: Interventional

This study is being carried out to study the efficacy and safety of treatment with melagatran injection followed by ximelagatran tablets in preventing blood clots, compared with enoxaparin for a period of 5-6 weeks. A separate visit, independent from the study will be done approximately 6 months after the surgery.

NCT ID: NCT00206063 Terminated - Clinical trials for Stroke Prevention in Patients With Atrial Fibrillation

Long Term Open Follow-up With H376/95 vs. Warfarin

Start date: August 1999
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate tolerability of long-term treatment with ximelagatran compared to standard treatment with warfarin.

NCT ID: NCT00204074 Active, not recruiting - Migraine Clinical Trials

Treatment of Menstrual Migraine With Sequential, Transdermal, 17-Beta-Estradiol. A Double-Blind, Randomised, Cross-Over Trial.

Start date: October 2001
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine whether transdermally administered 17-beta estradiol sequentially could reduce the number of, and severity of, menstrual migraine attacks.

NCT ID: NCT00200005 Completed - Clinical trials for Fecal Incontinence and Constipation

Sacral Nerve Stimulation for Anal Incontinence and Bowel Control

MDT-301
Start date: November 1998
Phase: Phase 4
Study type: Interventional

Multicenter European study to evaluate efficacy and safety of sacral nerve stimulation with InterStim Therapy to treat fecal incontinence or constipation

NCT ID: NCT00196924 Completed - Clinical trials for Infections, Papillomavirus

Human Papilloma Virus Vaccine Safety and Immunogenicity Trial in Young Adolescent Women With GSK Bio HPV-16/18.

Start date: June 2004
Phase: Phase 3
Study type: Interventional

Human Papilloma virus (HPV) are viruses that cause a common infection of the skin and genitals in men and women. Several types of HPV infection are transmitted by sexual activity and, in women, can infect the cervix (part of the uterus or womb). This infection often goes away by itself, but if it does not go away (this is called persistent infection), it can lead in women over a long period of time to cancer of the cervix. If a woman is not infected by HPV, it is very unlikely that she will get cervical cancer. This study will evaluate the safety and immunogenicity of GSK Biologicals HPV-16/18 vaccine over 12 months, in pre-teen and adolescent women of 10-14 years of age at study start. Approximately 2000 study subjects will receive the HPV vaccine or a control vaccine (hepatitis A vaccine) administered intramuscularly according to a 0-1-6 month schedule.