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NCT ID: NCT00751062 Completed - Ocular Hypertension Clinical Trials

A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within Scandinavia

Start date: November 1992
Phase: Phase 3
Study type: Interventional

PhXA41 is not inferior to timolol in reducing intra-ocular pressure

NCT ID: NCT00750880 Completed - Clinical trials for Rheumatoid Arthritis

An Exploratory Study of Tocilizumab in Patients With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Current Non-Biologic DMARDs and/or Anti-TNF Therapy.

Start date: September 2008
Phase: Phase 3
Study type: Interventional

This open-label, single arm study will investigate the safety, tolerability and efficacy of tocilizumab monotherapy, or combination therapy with non-biologic disease modifying antirheumatic drugs (DMARDs), in patients with severe active RA. Patients will receive tocilizumab 8mg/kg iv as a 60 minute infusion every 4 weeks for a total of 6 infusions. The anticipated time on study treatment is 3-12 months, and the target sample size is >500 individuals.

NCT ID: NCT00748982 Completed - Clinical trials for Left Ventricle Function

Investigate the Effect of AZD1305 on Patients With Left Ventricular Dysfunction

Start date: August 2008
Phase: Phase 2
Study type: Interventional

To explore if AZD1305 compromises left ventricular performance in patients with left ventricular dysfunction

NCT ID: NCT00748670 Terminated - Jaw, Edentulous Clinical Trials

Treatment With Fixture Microthread™ in Patients With Poor Bone Quality and no Teeth in the Upper Jaw, When Using Two-Stage Surgery

Start date: September 1999
Phase: N/A
Study type: Interventional

The primary objective of the study is to evaluate the long-term survival rate of individual implants and prostheses when treating edentulous upper jaws of poor bone quality with Fixture MicroThread™ (Micro-Macro). Clinical study recruitment was stopped in year 2000 due to a decision to modify the product under study. This was a result of feedback regarding the subjective feeling during the installation procedure. There were no safety concerns w/r to the study products. Patients already included and treated in the study were monitored for the full duration of the study in accordance with the clinical study protocol.

NCT ID: NCT00748397 Terminated - Jaw, Edentulous Clinical Trials

Evaluation of Treatment With Fixture Microthread™ in Patients Missing All Teeth in the Upper Jaw, When Using One-Stage Surgery

Start date: January 1999
Phase: N/A
Study type: Interventional

The primary objective of the study is to evaluate the long-term survival rate of implants and prostheses when treating totally edentulous upper jaws with Fixture MicroThread (Micro-Macro) using a one-stage surgical procedure. Clinical study recruitment was stopped in year 2000 due to a decision to modify the product under study. This was a result of feedback regarding the subjective feeling during the installation procedure. There were no safety concerns w/r to the study products. Patients already included and treated in the study were monitored for the full duration of the study in accordance with the clinical study protocol.

NCT ID: NCT00748189 Terminated - Clinical trials for Leukaemia, Lymphocytic, Chronic

Ofatumumab + Chlorambucil vs Chlorambucil Monotherapy in Previously Untreated Patients With Chronic Lymphocytic Leukemia

COMPLEMENT 1
Start date: December 22, 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the safety and efficacy of ofatumumab added to chlorambucil in patients with untreated Chronic Lymphocytic Leukemia.

NCT ID: NCT00748033 Completed - Clinical trials for Urinary Catheterization

A Study Evaluating a Urinary Catheter With Different Activation Times for the Wetting Solution, in Healthy Male Volunteers.

Start date: August 2008
Phase: N/A
Study type: Interventional

The primary purpose of this study is to compare the subject's perception (separately for each randomized catheter) of practicing catheterization when using catheters with sodium chloride in wetting solution (using two different activation times) with a standard reference catheter. The hypothesis is that the subjects' perception of catheterization is the same or more positive when using the test catheters compared to the reference catheter.

NCT ID: NCT00747942 Completed - Overweight Clinical Trials

Support for Increased Physical Activity (Stöd Till Aktivare Motion)

STAM
Start date: October 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to improve and analyze the level of physical activity in immigrant women from the Middle East and Latin America living in Sweden. The investigators will also investigate if glucose, insulin, and lipid metabolism; stress-related hormone production; and subclinical inflammatory activity are affected by the intervention. The follow-up period is 2 years.

NCT ID: NCT00746681 Completed - Overactive Bladder Clinical Trials

Investigation of Tolterodine, Pregabalin and a Tolterodine - Pregabalin Combination for the Treatment of Overactive Bladder

Start date: December 2005
Phase: Phase 2
Study type: Interventional

Tolterodine is approved for use in the treatment of overactive bladder (OAB). The study is designed to a investigate whether pregabalin may have efficacy in OAB and whether the efficacy is altered when it is combined with tolterodine.

NCT ID: NCT00745693 Completed - Coronary Disease Clinical Trials

The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin

Start date: March 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to identify the role of endothelin 1 (a natural vasoconstrictor) in the adverse vascular effects demonstrated after exposure to air pollution