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NCT ID: NCT01229436 Completed - Clinical trials for Dupuytren's Contracture

Treatment Of Dupuytren's Contracture With Collagenase Clostridium Histolyticum Injection (Xiapex)

POINT X
Start date: December 2010
Phase: Phase 3
Study type: Interventional

This study will evaluate the impact of Xiapex treatment on the range of motion (ROM) of the affected fingers and the patient and physician reported treatment satisfaction and disease severity and their relation to ROM. Recovery to normal activities, recovery time (How long overall, time to use hand, time to return to work or daily activities, amount of work or daily activity time missed or reduced and affects on productivity and daily activities) will be assessed via patient diary. Use of concomitant analgesic medications will be recorded and total healthcare resource utilization (HCRU).

NCT ID: NCT01228682 Active, not recruiting - SIADH Clinical Trials

Post-Authorisation Safety Study of Samsca (Tolvaptan) Used in Routine Medical Practice

Start date: October 2010
Phase: N/A
Study type: Observational

A Drug Utilisation Survey is performed to monitor and document the drug utilisation patterns of Samsca in routine medical practice. A Post-Authorisation Safety Study is performed to collect information on the safety of Samsca when used in a real-life setting.

NCT ID: NCT01228669 Completed - Healthy Clinical Trials

Safety of NNC 0172-0000-2021 in Healthy Male Subjects and Subjects With Haemophilia A or B

Explorer 1
Start date: October 25, 2010
Phase: Phase 1
Study type: Interventional

This trial is conducted in Europe and Asia. The aim of this clinical trial is to investigate the safety, pharmacokinetics (how the trial drug is distributed in the body) and pharmacodynamics (physiological effects of the drug on the body) of NNC 0172-0000-2021 administered intravenously and subcutaneously to healthy male subjects and subjects with haemophilia A or B

NCT ID: NCT01228617 Completed - Tobacco Dependence Clinical Trials

Single-dose Pharmacokinetics of Oral Nicotine Replacement Products

Start date: September 2007
Phase: N/A
Study type: Interventional

This is an explorative study comparing new prototypes of Nicotine Replacement Products with Nicorette® gum.

NCT ID: NCT01227720 Completed - Tobacco Dependence Clinical Trials

Comparative Pharmacokinetic Study of New Oral Nicotine Replacement Therapy Products.

Start date: August 2009
Phase: N/A
Study type: Interventional

Comparative pharmacokinetic study of new oral nicotine replacement therapy products.

NCT ID: NCT01227629 Completed - Atrial Fibrillation Clinical Trials

PETRO Stroke Prevention in Patients With AF by Treatment With Dabigatran, With and Without Aspirin, Compared to Warfarin

Start date: September 2003
Phase: Phase 2
Study type: Interventional

The purpose of this trial is to evaluate the safety of different doses of BIBR 1048, alone or in combination with acetylsalicylic acid (ASA), as determined by the rates of bleeding and other adverse events. A secondary objective of this trial is to evaluate the anticoagulant effect of different doses of BIBR 1048, based on the reduction of plasma concentrations of D-dimer, a laboratory marker for activated coagulation in patients with atrial fibrillation (AF), and to correlate bleeding and other events with pharmacokinetic (PK) and pharmacodynamic (PD) data.

NCT ID: NCT01227356 Completed - Health Care Quality Clinical Trials

A Study Comparing Imatinib and Imatinib/Pegylated Interferon in Chronic Myeloid Leukemia

Start date: September 2004
Phase: Phase 2
Study type: Interventional

Patients with chronic myeloid leukemia in imatinib induced CHR are randomized between imatinib 400 mg daily and imatinib 400 mg daily + PegIntron 30 ug weekly. Primary endpoint: To compare at 12 months between the treatment arms the rate of Major Molecular Response (=99,9% tumour reduction) at 12 months

NCT ID: NCT01226784 Completed - Fibromyalgia Clinical Trials

The Effects of Training and Relaxation on Fibromyalgia.

Start date: October 2010
Phase: N/A
Study type: Interventional

Effects of physical training and relaxation exercise on pathophysiological mechanisms and symptoms in finbromyalgia patients.

NCT ID: NCT01226771 Completed - Hepatitis C Clinical Trials

Ribavirin Loading Dose or Priming and Concentration Targeting for HCV Genotype 1

RibaC
Start date: September 2010
Phase: Phase 3
Study type: Interventional

This is a randomized, open-label, parallel group, multicenter pilot study evaluating the efficacy and safety of alternative dosing of ribavirin vs. standard of care dosing in combination with peginterferon alpha-2a in interferon naïve patients with chronic hepatitis c genotype 1 infection.

NCT ID: NCT01226602 Completed - Clinical trials for Coronary Flow Velocity

Study to Assess the Effect of Ticagrelor on Coronary Blood Flow in Healthy Male Subjects.

Start date: December 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if Ticagrelor increases the Adenosin induced coronary blood flow velocity.