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NCT ID: NCT04075006 Completed - Critical Illness Clinical Trials

Analgosedative adjuncT keTAmine Infusion iN Mechanically vENTilated ICU Patients

ATTAINMENT
Start date: August 28, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the efficacy and safety of a low dose ketamine infusion used in combination of standard of care in critically ill patients to test whether ketamine can help to shorten the time of being in breathing tube and ventilator compared to the standard of care alone.

NCT ID: NCT04073030 Completed - Burns Clinical Trials

Burn Injury In a Child Due to Cyanoacrylate-Based Nail Glue- Case Report and Literature Review

Cyanoacrylate
Start date: June 1, 2019
Phase:
Study type: Observational

Cyanoacrylate is used in the manufacturing of surgical adhesives, nail glue and super glue. After contact with cotton or wool, among other substances, a reaction is ignited, inflicting thermal damage to the skin underlying clothes. Nine papers have been published about such an incidence, majority of which involve children. In this paper, a four-year-old girl suffering from mixed-first-and-second degree burns due to cyanoacrylate spillage over the digits, anterior aspect of the right thigh and a patch of the skin on the left upper abdomen, spanning 4% of the total body surface area. The clothes were forcefully removed by the mother and shampoo was applied over the area. In the ER, irrigation with normal saline was done followed by dressing with paraffin- impregnated gauzes and silver sulfadiazine. Volar slabs were placed on the hands. The dressing in the hands was later changed to fusidic acid as the burn healed. Silicone sheet dressing was initiated twenty-eight days later after complete healing of the burned skin. An experiment conducted by the authors showed no difference in the pH of different cyanoacrylate products. The pH was not changed after applying shampoo over the nail glue immersed dip-stick. This paper aims to improve awareness about proper first-aid management which predicts the quality of the outcome. Further emphasis is required on providing a safe environment for the children and clear, comprehendible warning of hazards on the label of the cyanoacrylate based-products.

NCT ID: NCT04060680 Completed - Tachycardia Clinical Trials

Extravascular ICD Pivotal Study

EV ICD
Start date: September 16, 2019
Phase: N/A
Study type: Interventional

Pivotal Summary: The study is designed to demonstrate safety and efficacy of the Extravascular Implantable Cardioverter Defibrillator (EV ICD) System. Continued Access Summary: This study is designed to provide continued access to the Extravascular Implantable Cardioverter Defibrillator (EV ICD) System.

NCT ID: NCT04042441 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Research Study, Looking at How Ryzodeg® (Insulin Degludec/Insulin Aspart) Works in People With Type 2 Diabetes in Local Clinical Practice

ARISE
Start date: July 29, 2019
Phase:
Study type: Observational

The purpose of the study is to collect information on how Ryzodeg® works in real world patients and to see if Ryzodeg® can lower blood sugar levels. Participants will get Ryzodeg® as prescribed to them by their doctor. The study will last for about 6 to 9 months. Participants will be asked questions about their health and their diabetes treatment as part of their normal doctor's appointment.

NCT ID: NCT04034017 Completed - Clinical trials for Gastroesophageal Reflux

Gastroesophageal Reflux Disease Among College Students

Start date: September 1, 2018
Phase:
Study type: Observational

Background: Gastroesophageal reflux disease (GERD) is a worldwide prevalent gastrointestinal disorder which has negative impacts on quality of life, health and economy. The aims of this study were to assess the prevalence of GERD among college students in southwestern Saudi Arabia and to evaluate its personal, academic and stress correlates Materials and Methods: Through a cross-sectional study design, a self-reported questionnaire was distributed between a representative sample of students in health and non-health care colleges in southwestern Saudi Arabia. The questionnaire included data for personal characteristics, academic study, and Arabic versions of GERD questionnaire (GerdQ) and Cohen's Perceived Stress Scale.

NCT ID: NCT04031859 Completed - Clinical trials for Total Knee Replacement Surgeries

Risk Stratification Procedure for Thromboembolism Prophylaxis

Start date: October 10, 2018
Phase: Phase 2
Study type: Interventional

The main objective for this study is validation for the proposed risk stratification tool, by evaluating the clinical outcomes for its use post TKR Surgeries. For this objective, the design that is used is Randomized Trial.

NCT ID: NCT04029480 Active, not recruiting - Clinical trials for Type 2 Diabetes Mellitus

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

Start date: October 8, 2019
Phase: Phase 3
Study type: Interventional

This study will evaluate the safety and efficacy of ertugliflozin (MK-8835) in pediatric participants with T2DM on metformin with/without insulin. The primary hypothesis of the study is that the addition of ertugliflozin reduces hemoglobin A1C (HbA1C) more than the addition of placebo after 24 weeks of treatment.

NCT ID: NCT04027816 Completed - Clinical trials for Neuroaxonal Dystrophy, Infantile

A Natural History Study of Infantile Neuroaxonal Dystrophy

Start date: June 17, 2019
Phase:
Study type: Observational

This study is a longitudinal and prospective study of the natural history of infantile neuroaxonal dystrophy (INAD).

NCT ID: NCT04022798 Recruiting - Low Back Pain Clinical Trials

Management of LBP With Radiculopathy.

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

This study is to determine the effectiveness of Neural mobilization(NM) technique compared with lumbar stabilization exercise (LSE) and Radial Extracorporeal Shock Wave Therapy (rESWT) in the physical therapy management of chronic low back pain (CLBP) with radiculopathy. Subjects will be randomly assigned into two groups. Group A (NM, LSE and rESWT) and Group B (LSE and rESWT).

NCT ID: NCT04010110 Completed - Clinical trials for Hydroxychloroquine Toxic Retinopathy

Hydroxychloroquine Dosing and Toxicity in Ophthalmology Clinics

Start date: June 1, 2017
Phase:
Study type: Observational

This study assesses the ocular toxicity in patients on high dose hydroxychloroquine (HCQ) as per the latest guidelines of the American Academy of Ophthalmology (AAO).