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NCT ID: NCT00148356 Completed - Clinical trials for Coronary Artery Disease

Safety and Efficacy of the ZoMaxx™ Drug-Eluting Stent System in Coronary Arteries

ZoMaxx™ I
Start date: September 2004
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the safety and efficacy of the ZoMaxx drug-eluting stent in patients with blockage of native coronary arteries. The study is designed to demonstrate non-inferiority to the TAXUS Express2 Paclitaxel-Eluting Stent that has proven superior to bare metal stents and is a recognized standard of care.

NCT ID: NCT00147602 Completed - Clinical trials for Cardiovascular Disease

Lipitor In The Prevention Of Stroke, For Patients Who Have Had A Previous Stroke

SPARCL
Start date: November 1998
Phase: Phase 4
Study type: Interventional

To determine whether Lipitor reduces stroke, compared to placebo in patients who have had a previous stroke or transient ischemic attack.

NCT ID: NCT00147004 Completed - Shock, Septic Clinical Trials

Corticosteroid Therapy of Septic Shock - Corticus

Corticus
Start date: March 2002
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine whether steroids decrease 28-day mortality in patients with septic shock.

NCT ID: NCT00146328 Completed - HIV Infections Clinical Trials

Rollover Trial Safety and Tolerability of Combination Tipranavir and Ritonavir Use in HIV 1 Infected Subjects

Start date: April 2001
Phase: Phase 2/Phase 3
Study type: Interventional

The objective of this study is to determine the long term safety and tolerability of multiple oral doses of tipranavir (Aptivus) and ritonavir with a focus on the long term safety of the development dose (500 mg tipranavir/200 mg ritonavir BID) when administered with other antiretroviral medications.

NCT ID: NCT00144794 Recruiting - Clinical trials for Mucopolysaccharidosis I (MPS I)

Mucopolysaccharidosis I (MPS I) Registry

Start date: November 20, 2003
Phase:
Study type: Observational

The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients receiving enzyme replacement therapy, such as Aldurazyme (Recombinant Human Alpha-L-Iduronidase), or other treatment modalities. The objectives of the Registry are: - To evaluate the long-term effectiveness and safety of Aldurazyme® (laronidase) - To characterize and describe the MPS I population as a whole, including the variability, progression, and natural history of MPS I - To help the MPS I medical community with the development of recommendations for monitoring patients and reports on patient outcomes to optimize patient care

NCT ID: NCT00144339 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Evaluation of the Long- Term Effects of Spiriva on Lung Function in COPD Patients

Start date: December 2002
Phase: Phase 3
Study type: Interventional

The primary objective of this trial is to determine whether daily treatment with tiotropium (Spiriva®, Bromuro de Tiotropio®) inhalation capsule via HandiHaler® reduces the rate of decline in lung function over time in patients with COPD.

NCT ID: NCT00144170 Completed - HIV Infections Clinical Trials

Tipranavir/Ritonavir vs. Genotypically Defined Protease Inhibitor/Ritonavir in HIV Patients (RESIST-2)

Start date: February 2003
Phase: Phase 3
Study type: Interventional

The objective of this study is to demonstrate the safety and efficacy of tipranavir/ritonavir versus an active control arm in highly treatment experienced Human immunodeficiency virus-1 infected patients. Patients must have a viral load > =1000 cells/mL, and genotype indicating at least one resistance conferring protease inhibitor-mutation as determined from a predefined panel of mutations. Any CD4+ count is acceptable.

NCT ID: NCT00143403 Completed - Clinical trials for Colorectal Neoplasms

Comparing Irinotecan and 5 FU/FA To 5-FU/FA After Resection Of Liver Metastases For Colorectal Cancer

Start date: December 2001
Phase: Phase 3
Study type: Interventional

To see if Disease Free Survival (DFS) is improved when complete surgical resection of liver metastases (R0) is followed by chemotherapy with CPT-11 and 5-FU/FA as FOLFIRI regimen, compared to 5-FU/FA alone.

NCT ID: NCT00143312 Completed - Clinical trials for Prophylaxis Of Invasive Fungal Infections

Voriconazole for Secondary Prophylaxis of Invasive Fungal Infections in Patients With Allogeneic Stem Cell Transplants

VOSIFI
Start date: February 2005
Phase: Phase 4
Study type: Interventional

To prevent recurrence of invasive fungal infection in patients with allogeneic stem cell transplants

NCT ID: NCT00143130 Completed - Seizures Clinical Trials

Pregabalin In Partial Seizures Extension Study

PREPS EXT
Start date: April 2005
Phase: Phase 3
Study type: Interventional

To evaluate long-term efficacy and safety of pregabalin (150 to 600mg/day) as adjunctive treatment in patients with partial seizures.