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NCT ID: NCT00442325 Completed - Clinical trials for Diabetes Mellitus, Type 2

Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets

ACTFAST 2
Start date: January 2003
Phase: Phase 4
Study type: Interventional

European physicians tend to always use the lowest dose of statins to initiate therapy even in subjects who require large reductions in cholesterol. The study evaluates if selecting the starting dose based on baseline and target LDL-C cholesterol would provide better results (ie proportion of subjects resching target)

NCT ID: NCT00441727 Completed - Gastric Ulcer Clinical Trials

Study of Esomeprazole 20 mg or 40 mg vs Placebo Effectiveness on the Occurrence of Peptic Ulcers in Subjects on Low Dose Acetylsalicylic Acid (LDA)

Oberon
Start date: February 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effect of esomeprazole 20 or 40 mg once daily versus placebo on the occurrence of peptic ulcers during 26 weeks in subjects on continuous low-dose acetylsalicylic acid.

NCT ID: NCT00439647 Completed - Male Osteoporosis Clinical Trials

Efficacy in Reducing Fractures and Safety of Zoledronic Acid in Men With Osteoporosis

Start date: December 2006
Phase: Phase 3
Study type: Interventional

This study will investigate if the drug zoledronic acid given once yearly is safe and has beneficial effects in treating osteoporosis by reducing bone loss and fractures in men with osteoporosis.

NCT ID: NCT00436033 Completed - Clinical trials for Fibromyalgia Syndrome

A Multicentre Trial to Determine the Efficacy and Safety of Milnacipran in the Treatment of Fibromyalgia Syndrome

Start date: February 2006
Phase: Phase 3
Study type: Interventional

Investigation of efficacy and safety of treatment with milnacipran in the treatment of fibromyalgia syndrome.

NCT ID: NCT00434148 Completed - Cushing's Disease Clinical Trials

Safety and Efficacy of Different Dose Levels of Pasireotide in Patients With de Novo, Persistent or Recurrent Cushing's Disease

Start date: December 2006
Phase: Phase 3
Study type: Interventional

This study will evaluate the safety and efficacy of two different doses of Pasireotide in patients with de novo or recurrent/persistent Cushing's Disease.

NCT ID: NCT00431769 Completed - Multiple Myeloma Clinical Trials

An Efficacy and Safety Study of Bortezomib Re-treatment in Multiple Myeloma

Start date: June 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of bortezomib in participants with multiple myeloma who have previously responded to a bortezomib based therapy.

NCT ID: NCT00431678 Completed - Pneumonia Clinical Trials

Efficacy and Safety of Sequential IV/PO Moxifloxacin in Comparison to IV Levofloxacin Plus IV Ceftriaxone Followed by PO Levofloxacin, in the Treatment of Patients With Community-acquired Pneumonia

Start date: January 2004
Phase: Phase 3
Study type: Interventional

Sequential therapy with intravenous to oral moxifloxacin, was tested at 69 study centres in 17 countries to determine if this treatment regimen is safe and effective in treating hospitalized adult patients with community-acquired pneumonia. 748 patients were participated in the study over an 18 months period. Individual patient involvement in the study was approximately 4-6 weeks. Moxifloxacin was compared to a combination treatment regimen of high dose intravenous ceftriaxone plus high dose intravenous levofloxacin followed by high dose oral levofloxacin.

NCT ID: NCT00430729 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease. Ratio-Study. (BY217/M2-112)

Start date: January 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the effect of 500mcg roflumilast vs placebo on exacerbation rate and pulmonary function as well as quality of life in patients with chronic obstructive pulmonary disease (COPD).

NCT ID: NCT00427934 Terminated - Clinical trials for Arthritis, Rheumatoid

Maraviroc in Rheumatoid Arthritis

Start date: February 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate whether maraviroc, an investigational drug given with methotrexate (MTX) is safe and effective in the treatment of rheumatoid arthritis in adult patients.

NCT ID: NCT00426660 Completed - Clinical trials for Advanced HIV Infection

Expanded Access Program for Maraviroc At Multiple Centers

Start date: February 2007
Phase: Phase 3
Study type: Interventional

To provide access to maraviroc to patients who have limited or no therapeutic treatment options and to collect more safety data in a broader patient population.