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NCT ID: NCT00148356 Completed - Clinical trials for Coronary Artery Disease

Safety and Efficacy of the ZoMaxx™ Drug-Eluting Stent System in Coronary Arteries

ZoMaxx™ I
Start date: September 2004
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the safety and efficacy of the ZoMaxx drug-eluting stent in patients with blockage of native coronary arteries. The study is designed to demonstrate non-inferiority to the TAXUS Express2 Paclitaxel-Eluting Stent that has proven superior to bare metal stents and is a recognized standard of care.

NCT ID: NCT00147602 Completed - Clinical trials for Cardiovascular Disease

Lipitor In The Prevention Of Stroke, For Patients Who Have Had A Previous Stroke

SPARCL
Start date: November 1998
Phase: Phase 4
Study type: Interventional

To determine whether Lipitor reduces stroke, compared to placebo in patients who have had a previous stroke or transient ischemic attack.

NCT ID: NCT00145769 Completed - Clinical trials for Adenocarcinoma of Rectum

A Randomised Trial of Preoperative Radiotherapy for Stage T3 Adenocarcinoma of Rectum

Start date: July 2001
Phase: Phase 3
Study type: Interventional

This is a multi-centre randomised trial comparing long course (LC) preoperative chemoradiation with short course (SC) preoperative radiotherapy for patients with localised T3 rectal cancer.

NCT ID: NCT00144339 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Evaluation of the Long- Term Effects of Spiriva on Lung Function in COPD Patients

Start date: December 2002
Phase: Phase 3
Study type: Interventional

The primary objective of this trial is to determine whether daily treatment with tiotropium (Spiriva®, Bromuro de Tiotropio®) inhalation capsule via HandiHaler® reduces the rate of decline in lung function over time in patients with COPD.

NCT ID: NCT00143611 Completed - Sepsis Clinical Trials

Efficacy & Safety of Resatorvid in Adults With Severe Sepsis

Start date: September 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the optimal dose of Resatorvid for reducing 28-day all-cause mortality in subjects with severe sepsis.

NCT ID: NCT00142298 Completed - Chronic Hepatitis B Clinical Trials

Telbivudine in Adults Previously Treated in Idenix-Sponsored Telbivudine Studies

Start date: March 2005
Phase: Phase 3
Study type: Interventional

This trial is being conducted as an open-label, extended-term study for patients with chronic hepatitis B who have previously completed an Idenix-sponsored trial with telbivudine.

NCT ID: NCT00141843 Completed - Hemophilia A Clinical Trials

Study to Establish Bioequivalence of ReFacto AF (BDDrFVIII) With Advate (FLrFVIII) in Hemophilia A

Start date: July 2005
Phase: Phase 3
Study type: Interventional

The study will consist of two parts: a safety and efficacy period in which all subjects will participate and a pharmacokinetic analysis period, in which 30 eligible subjects will participate to compare ReFacto AF and Advate bioequivalency and safety and efficacy of ReFacto AF in patients with Hemophilia A.

NCT ID: NCT00141648 Completed - Osteolymphoma Clinical Trials

Chemotherapy and Radiotherapy for Osteolymphoma

Start date: September 2000
Phase: N/A
Study type: Interventional

This trial is intended to determine the results obtained when standard treatment for Non Hodgkin's lymphoma is applied to the disease in a rare subtype which arises in bone. Patients in the study undergo a detailed assessment, then treatment with chemotherapy and radiotherapy, followed by close monitoring.

NCT ID: NCT00140582 Completed - Follicular Lymphoma Clinical Trials

Primary Rituximab and Maintenance

Start date: December 2004
Phase: Phase 3
Study type: Interventional

- Objectives - Primary objective: To evaluate in patients with advanced follicular lymphoma the benefit of maintenance therapy with rituximab after induction of response with chemotherapy plus rituximab in comparison with no maintenance therapy - Secondary objective: To evaluate response rates, event driven survival endpoints (EFS, PFS, OS) and quality of life of four different chemotherapy regimens combined with rituximab, with or without maintenance with rituximab, for first line treatment of advanced stage follicular lymphoma. - Study Design This is an international open-label, multicentre, randomized study with two treatment phases. In the induction phase patients have to respond to 1st line induction treatment in order to be eligible for randomization to the second phase of maintenance treatment or observation. After the maintenance period patients will be included in the follow up phase for 3 years.

NCT ID: NCT00140101 Completed - Clinical trials for Coronary Artery Disease

Safety and Efficacy of the ZoMaxx™ Drug-Eluting Stent System in Coronary Arteries

ZoMaxx™ II
Start date: May 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to demonstrate the safety and efficacy of the ZoMaxx drug-eluting stent in patients with blockage of native coronary arteries. The study is designed to demonstrate non-inferiority to the TAXUS Express2 Paclitaxel-Eluting Stent that has proven superior to bare metal stents and is a recognized standard of care.