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NCT ID: NCT00151788 Terminated - Atherosclerosis Clinical Trials

Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Carotid Artery Disease. This Study is Also Known as CAPTIVATE.

Start date: February 2004
Phase: Phase 2/Phase 3
Study type: Interventional

The effects of pactimibe versus placebo on the progression of atherosclerosis in the carotid arteries will be assessed using standard ultrasound techniques.

NCT ID: NCT00148252 Terminated - Clinical trials for Renal Transplantation

Lowering Total Immunosuppressive Load in Renal Transplant Recipients More Than 12 Months Posttransplant

Start date: February 2003
Phase: Phase 4
Study type: Interventional

To compare the change in renal function between CsA or MMF withdrawal from before to 12 months after drug withdrawal in renal transplant recipients on triple immunosuppressive therapy

NCT ID: NCT00137345 Terminated - Kidney Transplant Clinical Trials

Study Comparing Sirolimus With Cyclosporine in a Calcineurin Inhibitor (CNI)-Free Regimen in Kidney Transplant Recipients

Start date: June 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if one drug is superior to another with regard to safety and the preservation of renal function after a kidney transplant.

NCT ID: NCT00128115 Terminated - Hip Fracture Clinical Trials

Treatment of Sarcopenia in Post-Hip Fracture Patients (0677-032)

Start date: September 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to demonstrate an improvement in physical functional recovery, following administration of Drug for 24 weeks, in patients who have recently experienced a hip fracture. This study will also evaluate the safety and tolerability of Drug. This is an early phase trial and some specific protocol information is proprietary and not publicly available at this time. (Full information is available to trial participants).

NCT ID: NCT00080132 Terminated - Clinical trials for Hypertriglyceridemia

Implitapide in Patients With Hypertriglyceridemia (HTG) on Maximal, Concurrent Triglyceride-Lowering Therapy

Start date: October 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if implitapide is effective in lowering triglyceride (TG) levels in patients with Fredrickson Type I or V hypertriglyceridemia where the maximum tolerable medication and diet were not sufficient.

NCT ID: NCT00079859 Terminated - Clinical trials for Familial Hypercholesterolemia

Implitapide in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) on Maximal Concurrent Lipid-Lowering Therapy

Start date: October 2003
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if implitapide, used in conjunction with other lipid-lowering therapies, is safe and effective when compared to placebo in lowering low-density lipoprotein cholesterol (LDL-C) in patients with heterozygous familial hypercholesterolemia (HeFH).

NCT ID: NCT00079846 Terminated - Clinical trials for Familial Hypercholesterolemia

Implitapide in Patients With Homozygous Familial Hypercholesterolemia (HoFH) on Maximal Concurrent Lipid-Lowering Therapy

Start date: September 2003
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if implitapide, used in conjunction with other lipid-lowering therapies, is safe and effective when compared to placebo in lowering low-density lipoprotein cholesterol (LDL-C) in patients with homozygous familial hypercholesterolemia (HoFH).

NCT ID: NCT00033644 Terminated - Sarcoma Clinical Trials

Combination Chemotherapy Plus Sargramostim in Treating Patients With Cancer of the Uterus

Start date: March 2002
Phase: Phase 2
Study type: Interventional

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Colony-stimulating factors such as sargramostim may increase the number of immune cells found in bone marrow or peripheral blood and may help a person's immune system recover from the side effects of chemotherapy. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus sargramostim in treating patients who have advanced, persistent, or recurrent cancer of the uterus.

NCT ID: NCT00030472 Terminated - Cervical Cancer Clinical Trials

Liposomal Doxorubicin in Treating Patients With Persistent or Recurrent Cancer of the Cervix

Start date: December 2001
Phase: Phase 2
Study type: Interventional

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness liposomal doxorubicin in treating patients who have persistent or recurrent cancer of the cervix.

NCT ID: NCT00020839 Terminated - Metastatic Cancer Clinical Trials

Temozolomide With or Without Radiation Therapy to the Brain in Treating Patients With Stage IV Melanoma That Is Metastatic to the Brain

Start date: April 2001
Phase: Phase 3
Study type: Interventional

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known if chemotherapy is more effective with or without radiation therapy in treating brain metastases. PURPOSE: Randomized phase III trial to compare the effectiveness of chemotherapy with or without radiation therapy to the brain in treating patients who have stage IV melanoma with asymptomatic brain metastases.