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NCT ID: NCT02799043 Completed - Clinical trials for Paroxysmal Atrial Fibrillation

Randomized Evaluation of Redo Ablation Procedures of Atrial Fibrillation With FIRM Guided Procedures

REDO-FIRM
Start date: June 2016
Phase: N/A
Study type: Interventional

A prospective, multicenter, randomized study to assess the safety and effectiveness of FIRM-guided procedures in conventional "redo" RF ablation procedures for the treatment of persistent and paroxysmal atrial fibrillation.

NCT ID: NCT02798471 Completed - Pulmonary Embolism Clinical Trials

Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE)

Start date: March 27, 2017
Phase: Phase 3
Study type: Interventional

This is an event driven Phase 3, prospective, randomized, open-label, blinded endpoint evaluation (PROBE) parallel group study in subjects with confirmed VTE. This study is designed to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of edoxaban and to compare the efficacy and safety of edoxaban against standard of care in pediatric subjects with confirmed VTE.

NCT ID: NCT02798003 Recruiting - Clinical trials for Non-small Cell Lung Cancer

Food Reward in Cachexia Induced by Acute or Chronic Disease

Start date: November 2016
Phase: N/A
Study type: Observational

To study activity in the reward-circuitry of the brain in patients suffering from cachexia induced by cancer or chronic disease.

NCT ID: NCT02797951 Completed - Clinical trials for Chronic Cluster Headache

A Study of LY2951742 (Galcanezumab) in Participants With Cluster Headache

Start date: July 13, 2016
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to assess the long-term safety and tolerability of galcanezumab administered up to once monthly in participants with episodic or chronic cluster headache who have completed study I5Q-MC-CGAL (NCT02397473) or study I5Q-MC-CGAM (NCT02438826).

NCT ID: NCT02796274 Completed - Clinical trials for Leber's Hereditary Optic Neuropathy (LHON)

Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON)

Start date: May 2016
Phase:
Study type: Observational

The purpose of this survey is to collect visual acuity data from patients with LHON in order to establish the clinical course (natural history) and visual acuity outcomes in patients with a genetically confirmed diagnosis of LHON. In addition, this survey will generate data that will serve as comparator for the open-label study SNT-IV-006.

NCT ID: NCT02796261 Active, not recruiting - Clinical trials for Anaplastic Astrocytoma

Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients

STELLAR
Start date: July 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of eflornithine in combination with lomustine, compared to lomustine taken alone, in treating patients whose anaplastic astrocytoma has recurred/progressed after radiation and temozolomide chemotherapy.

NCT ID: NCT02795676 Completed - Fabry Disease Clinical Trials

Study of the Safety and Efficacy of PRX-102 Compared to Agalsidase Beta on Renal Function

BALANCE
Start date: June 2016
Phase: Phase 3
Study type: Interventional

This was a randomized, double-blind, active control study of the enzyme replacement therapy (ERT) drug PRX-102 (pegunigalsidase alfa) in Fabry disease patients with impaired renal function. Patients who had been treated for approximately 1 year with agalsidase beta and who had been on a stable dose of that product for at least 6 months were randomized in a 2:1 ratio to either switch to PRX-102 or to continue treatment with agalsidase beta. Both treatments were delivered by intravenous infusions every two weeks, at a dosage of 1 mg/kg.

NCT ID: NCT02795325 Terminated - Clinical trials for Primary Hyperoxaluria Type 1

A Study of DCR-PH1 in Patients With Primary Hyperoxaluria Type 1 (PH1)

Start date: May 13, 2016
Phase: Phase 1
Study type: Interventional

A phase 1 study of DCR-PH1 in patients with primary hyperoxaluria type 1 (PH1) to determine the safety, tolerability, pharmacokinetic (PK) and pharmacodynamics (PD) effects of DCR-PH1 administered via-intravenous infusion (IV)

NCT ID: NCT02793349 Terminated - Ischemia Clinical Trials

The ABSORB Bioresorbable Scaffold Below the Knee (BTK) Study

Start date: June 2015
Phase: N/A
Study type: Interventional

ABSORB BTK Study: A prospective, multicenter, controlled clinical evaluation of the use of a bioresorbable drug eluting stent in the arterial vasculature below the knee

NCT ID: NCT02793310 Completed - Clinical trials for Fuchs' Endothelial Dystrophy

DMEK Versus DSAEK Study

DMEK
Start date: October 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether corneal transplantation by Descemet Membrane Endothelial Keratoplasty more favourable and cost-effective is compared to Descemet Stripping Automated Endothelial Keratoplasty for Fuchs Endothelium Corneal Dystrophy.