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NCT ID: NCT03697798 Completed - Pertussis Clinical Trials

A Study Exploring Whooping Cough Protection in Children and Adults

BERT
Start date: April 18, 2018
Phase: Phase 4
Study type: Interventional

This study aims to investigate the effects of aP booster vaccination in children, young adults and elderly on the (long-term) immune response to B. pertussis in three European countries with a different epidemiological background and primary vaccination schedule for pertussis.

NCT ID: NCT03697707 Active, not recruiting - Clinical trials for Acute Myeloid Leukemia in Remission

Efficacy and Safety of Immunotherapy With Allogeneic Dendritic Cells, DCP-001, in Patients With Acute Myeloid Leukaemia

ADVANCE-II
Start date: October 15, 2018
Phase: Phase 2
Study type: Interventional

Phase II study to evaluate safety and efficacy of DCP-001 in patients with AML in CR, and with presence of MRD

NCT ID: NCT03697213 Completed - Palliative Care Clinical Trials

The Surprise Study

Start date: March 25, 2019
Phase:
Study type: Observational

This study investigates the use of the Surprise Question [SQ] (would you be surprised if this patient were to die in the next 12 months?) in routine practice. In particular, the study will investigate the consistency of the responses to the SQ and the relationship with the subsequent course of action decided upon.

NCT ID: NCT03697109 Completed - Cushing Syndrome Clinical Trials

A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome

GRACE
Start date: November 15, 2018
Phase: Phase 3
Study type: Interventional

This is a Phase 3, double-blind, placebo-controlled, randomized-withdrawal study to assess the efficacy, safety and pharmacokinetics (PK) of relacorilant in patients with endogenous Cushing syndrome and concurrent type 2 diabetes mellitus/impaired glucose tolerance and/or uncontrolled hypertension

NCT ID: NCT03696836 Terminated - Clinical trials for Osteo Arthritis Knee

AIR (Artificial Implant for Medial Meniscus Replacement) Study

AIR
Start date: October 11, 2018
Phase: N/A
Study type: Interventional

The AIR Study is a multi-center, prospective, interventional clinical trial with the objective to evaluate the safety and performance of the Trammpolin® meniscus prosthesis system.

NCT ID: NCT03695484 Active, not recruiting - Atrial Fibrillation Clinical Trials

Registry Evaluating AF Ablation Techniques

PRIME-AF
Start date: October 31, 2018
Phase:
Study type: Observational [Patient Registry]

The purpose of this observational registry is to prospectively collect procedure efficiency, safety and acute and long term outcome data from catheter ablation procedures as treatment of paroxysmal atrial fibrillation, using the following treatment modalities: - Cryoballoon ablation - Manual guided RF ablation using Contact Force catheters - Remote Magnetic Navigation guided RF ablation with e-Contact and high power settings - Remote Magnetic Navigation guided RF ablation with e-Contact and low power settings

NCT ID: NCT03695185 Completed - Clinical trials for Ulcerative Colitis (UC)

A Study to Investigate How Well Ravagalimab (ABBV-323) Works and How Safe it is in Participants With Moderate to Severe Ulcerative Colitis Who Failed Prior Therapy

Start date: March 26, 2019
Phase: Phase 2
Study type: Interventional

Study M15-722 is a Phase 2a study to investigate the efficacy and safety of Ravagalimab (ABBV-323) in participants with moderate to severe UC who failed prior therapy.

NCT ID: NCT03695094 Completed - Epilepsy Clinical Trials

A Study in Participants With Epilepsy, to Evaluate the Pharmacokinetics, Safety and Tolerability of Oxcarbazepine on Padsevonil

Start date: September 18, 2018
Phase: Phase 1
Study type: Interventional

The purpose of the study is to evaluate the effect of stable coadministered oxcarbazepine (OXC), on the pharmacokinetics (PK), safety, tolerability of padsevonil (PSL) and the plasma PK of PSL metabolites, UCB1431322-000 and UCB1447499-000, in study participants with epilepsy compared with study participants co-medicated with stable doses of levetiracetam (LEV), lamotrigine (LTG) or brivaracetam (BRV) therapy.

NCT ID: NCT03694210 Completed - Acute Pancreatitis Clinical Trials

EndoRotor DEN (Direct Endoscopic Necrosectomy)Trial

Start date: November 15, 2018
Phase: N/A
Study type: Interventional

A prospective, single arm, open label, multi-center, trial to evaluate the safety and effectiveness of the Interscope EndoRotor® Resection System in subjects requiring direct endoscopic necrosectomy (DEN) with walled off pancreatic necrosis (WOPN).

NCT ID: NCT03693170 Completed - Clinical trials for BRAF V600E-mutant Metastatic Colorectal Cancer

Encorafenib, Binimetinib and Cetuximab in Subjects With Previously Untreated BRAF-mutant ColoRectal Cancer

ANCHOR-CRC
Start date: January 17, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of the combination of study drugs encorafenib, binimetinib and cetuximab in patients who have BRAF V600 mutant metastatic colorectal cancer and have not received any prior treatment for their metastatic disease.