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NCT ID: NCT00809354 Terminated - Osteoarthritis Clinical Trials

Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or Hip

Start date: February 12, 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the long-term analgesic efficacy and safety of tanezumab for patients with osteoarthritis (OA) of the knee or hip currently experiencing partial benefit from, and are tolerating, non-steroidal anti-inflammatory drug (NSAID) therapy.

NCT ID: NCT00808132 Completed - Osteoporosis Clinical Trials

Study Evaluating The Effects Of Bazedoxifene/Conjugated Estrogens On Endometrial Safety And Postmenopausal Osteoporosis

Start date: January 2009
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to evaluate the safety and effectiveness of this investigational drug for the treatment of menopausal symptoms while protecting the endometrium (uterine lining) and preventing postmenopausal osteoporosis. Subject participation will last approximately 14.5 months.

NCT ID: NCT00807326 Completed - Diarrhea Clinical Trials

A Comparison of Three Medications to Treat Diarrhea in Adults.

Start date: November 2008
Phase: Phase 4
Study type: Interventional

A comparison of three medications to treat diarrhea in adults.

NCT ID: NCT00806819 Completed - Clinical trials for Carcinoma, Non-Small-Cell Lung

Lume Lung 2 : BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC

Start date: December 2008
Phase: Phase 3
Study type: Interventional

The trial will be performed to evaluate if BIBF 1120 in combination with standard pemetrexed therapy is more effective than placebo (inactive capsule) plus standard pemetrexed therapy in patients with stage IIIB, IV or recurrent NSCLC. Safety information about BIBF1120/pemetrexed will be obtained.

NCT ID: NCT00805467 Terminated - Clinical trials for Rheumatoid Arthritis

Open-Label, Multicenter Extension Study for Patients Completing Treatment Phase of a Rigel-Sponsored R935788 Studies

Start date: August 2008
Phase: Phase 2
Study type: Interventional

The purpose of this new research study is to gain additional information about how safe and effective R935788 is over a longer period of time.

NCT ID: NCT00804986 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study for Patients With Type 2 Diabetes Mellitus

Start date: December 2008
Phase: Phase 2
Study type: Interventional

A multicenter, multinational, randomized,double-blind, placebo-controlled study in patients with Type 2 Diabetes Mellitus (T2DM). Patients with inadequate glycemic control using diet and exercise alone, or in combination with metformin, will be enrolled. The primary objective of this study is to test the hypothesis that LY2428757 given to patients with T2DM inadequately controlled with diet and exercise alone, or metformin monotherapy, produces a significant decrease in the mean hemoglobin A1c (HbA1c) from baseline to endpoint at 12 weeks as compared to placebo. Trial consists of 12 weeks of double-blind treatment and 4-week safety follow-up.

NCT ID: NCT00804869 Withdrawn - Axial Length (AL) Clinical Trials

A-mode vs PalmScan Ultrasonography: Biometric Measurements.

Start date: October 2008
Phase:
Study type: Observational

Ultrasonography has become a critical ancillary test in the clinical practice of ophthalmology. It is commonly used as a standardized method for assessing intraocular biometry. The PalmScan ultrasonography (PsU) is a portable A-scan device that uses the same principles as the standard A-scan. The aim of the study is to compare the reliability of their measurements, in order to use them indistinctively.

NCT ID: NCT00804323 Terminated - Open-Angle Glaucoma Clinical Trials

PASCAL Trabeculoplasty

Start date: December 2007
Phase: N/A
Study type: Interventional

Argon laser trabeculoplasty (ALT) with 100 ms pulses is an effective therapy for lowering intraocular pressure (IOP). Similar reductions in IOP have been achieved using ns (SLT) and microsecond (MLT) pulses, which produce less thermal damage to trabecular meshwork (TM). Lack of clinically visible changes may make the accurate alignment of subsequent pulses difficult. We describe a novel technique - Patterned Laser Trabeculoplasty (PLT) using the PASCAL Photocoagulator system, and its preliminary evaluation in patients with open angle glaucoma.

NCT ID: NCT00804206 Terminated - Macular Edema Clinical Trials

Comparison of the Effects of Bevacizumab Before vs After Pattern Panretinal Photocoagulation

Start date: July 2008
Phase: Phase 4
Study type: Interventional

Compare the effect of an intravitreal injection of bevacizumab previous or posterior of panretinal laser photocoagulation (PRLP) with a pattern laser; to prevent and reduce diabetic macular edema (DME) in patients with proliferative diabetic retinopathy (PDR) with DME.

NCT ID: NCT00803153 Withdrawn - Clinical trials for Choroidal Detachment

PASCAL: Safety and Complications, Experience After 1301 Consecutive Cases

Start date: December 2008
Phase:
Study type: Observational

To report the safety and incidence of adverse effects, during and after a successful photocoagulation for different pathologies using a Pattern Scan Laser (PASCAL) system and its modified settings