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NCT ID: NCT05813613 Completed - Fatigue Clinical Trials

Role of Artificial Intelligence in Predicting Muscle Fatigue Using Virtual Reality Training

Start date: April 15, 2023
Phase:
Study type: Observational

The goal of this observational predicted study is to predict muscle fatigue using a specific AI algorithm in healthy vs post Covid-19 infected individuals. The main question it aims to answer is: Can Artificial Intelligence be used as a reliable source of predicting localized muscle fatigue in healthy vs post Covid-19 infected individuals? Participants will be divided into two groups: A healthy group and a post Covid-19 group. - Each group will undergo a familiarization process before the start of the exercises. - Then, each group will perform squatting exercises guided by the kynpasis virtual reality apparatus. - sEMG for the vastus lateralis and rectus femories, chest expansion, and goniometric measurements of the knee will be taken during different reported fatigue levels using the Biopac system. - Groups will continue squatting while recording their subjective fatigue levels using the Borg scale. - Data will then be run through machine learning processes to produce an AI algorithm capable of predicting isolated muscle fatigue.

NCT ID: NCT05768243 Completed - Clinical trials for Periodontitis Chronic Generalized Severe

Hyaluronic Acid Versus Red Injectable Platelet Rich Fibrin in Treatment of Periodontitis

Start date: March 1, 2021
Phase: Phase 4
Study type: Interventional

the aim of this clinical trial is to compare the efficacy of hyaluronic acid (HA) used as an adjunctive to scaling and root planing (SRP) and red injectable platelet rich-fibrin (i-PRF) in the non-surgical treatment of stage III periodontitis. The main question it aims to answer is: is there a difference between HA and red i-prf when used as an adjunct to SRP in terms of efficacy? Participants who are eligible will be assigned to one of the treatment groups: - Group 1= receives HA+ SRP - Group 2= receives red i-prf + SRP - Group 3= receives only SRP Researchers will compare Groups 1,2 and 3 to see if there's a difference in the periodontal parameters measured.

NCT ID: NCT05767034 Recruiting - Clinical trials for Polymyalgia Rheumatica

Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR)

REPLENISH
Start date: March 22, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the efficacy and safety of secukinumab 300 milligram (mg) and 150 mg administered subcutaneously (s.c.) for 52 weeks in combination with prednisone tapered over 24 weeks in adult participants with PMR who have recently relapsed.

NCT ID: NCT05761730 Recruiting - Clinical trials for Irreversible Pulpitis

Oral Dexamethasone for the Management of Symptomatic Irreversible Pulpitis Without Performing Pulpotomy

Start date: February 15, 2023
Phase: Phase 1
Study type: Interventional

The efficacy of short course orally administered dexamethasone on the reduction of pain before conventional pulpotomy has not yet been demonstrated. Therefore, the aim of this randomized clinical study is to assess the effect of dexamethasone on the reduction of pain in mandibular molars with irreversible pulpitis, without performing conventional pulpotomy in comparison to pain following pulpotomy.

NCT ID: NCT05756010 Recruiting - Clinical trials for Temporomandibular Disorder

Effect of Forward Head Correction on EMG of Masticatory Muscles in Patients With TMD

Start date: June 7, 2023
Phase: N/A
Study type: Interventional

This study aims to investigate the effects of forward head correction exercises on EMG of masticatory and cervical muscles in patients with temporomandibular disorder. The study's design will be double-blinded, randomized controlled trial. Patients suffering from TMD will be included in the program. The participants will allocate to one of two groups at random: the experimental group will perform a program consisting of two strengthening exercises (deep cervical flexors and shoulder retractors) and two stretchings (cervical extensors and pectoral muscles) and the control group will receive only neck flexion exercise.. This exercise program will be repeated 4 times per week for 10 weeks, and each session lasted for 30 minutes. The muscle activity EMG of masseter, temporalis, splenius, upper trapezius, and SCM will be measured pre and post-assessment using a biopic data acquisition system.

NCT ID: NCT05729022 Not yet recruiting - Clinical trials for Radiculopathy Lumbar

Ultrasound-Guided Microendoscopic Versus Fluoroscopic-Guided Lumbar Transforaminal Epidural Steroid Injections

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the Microendoscopic combined with ultrasound technique to the standard routinely used X-ray guided transforaminal steroid injection technique.

NCT ID: NCT05693402 Completed - Surgery Clinical Trials

Opioid-Free Anesthesia in Modified Radical Mastectomy

Start date: January 1, 2018
Phase:
Study type: Observational

The aim of this study is to evaluate the efficacy of opioid-free general anesthesia for breast surgeries in female patients.

NCT ID: NCT05682378 Recruiting - Clinical trials for Heterozygous or Homozygous Familial Hypercholesterolemia

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Adolescent ORION-16 or ORION-13 Studies

V-PEDS-OLE
Start date: February 10, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this open-label, single arm, multicenter extension study is to evaluate the long-term safety and tolerability of inclisiran in participants with HeFH or HoFH who have completed the ORION-16 or ORION-13 studies.

NCT ID: NCT05646784 Recruiting - Mood Disorders Clinical Trials

Gut Microbiota in Mood Disorders in Lebanese Population

Start date: January 24, 2024
Phase: N/A
Study type: Interventional

This study aims to evaluate the pathophysiological aspects of the role of inflammation and gut microbiota in mood disorders, in particular in depression, and their therapeutic implications on a cohort of the Lebanese population. Specific objective: The evaluation of probiotic intake (CEREBIOME®, Lallemand Health Solutions Inc., Mirabel, Canada) on depressive patients and the inflammatory state. Evaluate the effect of oral intake of a probiotic agent, on clinical and plasma inflammatory markers, in a subgroup of target patients versus a subgroup treated with placebo, in combination with conventional treatment.

NCT ID: NCT05628389 Recruiting - Smoking Cessation Clinical Trials

Phone Enabled Implementation of Cessation Support (PHOENICS)

Start date: March 7, 2024
Phase: N/A
Study type: Interventional

The tobacco use burden in Lebanon is exceptionally high: 35% of adults are current cigarette smokers and 39% are current waterpipe smokers. Although the World Health Organization endorses evidence-based interventions for population-level tobacco dependence treatment, recommended treatments are not integrated as a routine part of primary care in Lebanon, as is the case in other low-resource settings. The objective of this proposal is to evaluate the comparative effectiveness of promising multi-component interventions for implementing evidence-based cessation treatment in Lebanon's national system of primary health care centers.