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NCT ID: NCT00586495 Completed - Clinical trials for Carcinoma, Renal Cell

Long-term Extension From RCC Phase II (11515)

Start date: December 2005
Phase: Phase 2
Study type: Interventional

Extension to study 11515 (NCT00661375) which was a multicenter study of sorafenib in patients with renal cell carcinoma (RCC).

NCT ID: NCT00585195 Completed - Clinical trials for Systemic Anaplastic Large-Cell Lymphoma

A Study Of Oral PF-02341066, A C-Met/Hepatocyte Growth Factor Tyrosine Kinase Inhibitor, In Patients With Advanced Cancer

PROFILE 1001
Start date: April 19, 2006
Phase: Phase 1
Study type: Interventional

PF-02341066 may work in cancer by blocking the cell growth, migration and invasion of tumor cells. PF-02341066 is a new class of drugs called c-Met/Hepatocyte growth factor receptor tyrosine kinase inhibitors. This compound is also an inhibitor of the anaplastic lymphoma kinase (called ALK) tyrosine kinase and ROS receptor tyrosine kinases. This research study is the first time PF-02341066 will be given to people. PF-02341066 is taken by mouth daily.

NCT ID: NCT00584779 Terminated - Clinical trials for PK Properties Of Gabapentin In Subjects With Impaired Renal Function

An Open Label Pharmacokinetic Study Of Gabapentin In Japanese Subjects With Renal Impairment Including Hemodialysis

Start date: October 2007
Phase: Phase 4
Study type: Interventional

To confirm the pharmacokinetics following administration of gabapentin to Japanese subjects with renal impairment, compare the results to Western study results and confirm the adaptive possibility of dose adjustment in US package insert to Japanese.

NCT ID: NCT00577824 Completed - Type 2 Diabetes Clinical Trials

Efficacy and Safety of Exenatide in Japanese Patients With Type 2 Diabetes Who Are Treated With Oral Antidiabetic(s)

Start date: January 2008
Phase: Phase 3
Study type: Interventional

This long term, placebo-controlled trial is intended to assess the efficacy and safety of exenatide, dosed twice a day, in Japanese patients with Type 2 Diabetes who are treated with oral antidiabetic(s) but not well controlled.

NCT ID: NCT00575471 Completed - Type 2 Diabetes Clinical Trials

Placebo Controlled Dose-Response Study of Rivoglitazone in Type 2 Diabetes

Start date: July 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy response of rivoglitazone HCl on the change in HbA1c after 12 weeks of treatment in patients with type 2 diabetes.

NCT ID: NCT00575172 Completed - Diabetes Mellitus Clinical Trials

Nippon Ultra-Rapid Insulin and Diabetic Complication Evaluation-Study (NICE-Study)

Start date: March 2003
Phase: N/A
Study type: Observational

For the purpose of comparing efficacy of intensive therapy between 1) ultrarapid-acting type insulin (insulin aspart) and 2) conventional rapid-acting type insulin (R), a Multicenter Open Label Randomized Controlled Trial was planned in Japan using the occurrence of cardiovascular events in patients with diabetes, a high risk factor, as an index.

NCT ID: NCT00575094 Completed - Clinical trials for Community-Acquired Infections

Study Evaluating the Safety and Efficacy of Intravenous Tigecycline to Treat Hospitalized Japanese Subjects

Start date: November 2007
Phase: Phase 3
Study type: Interventional

To purpose of this study is to assess the safety and tolerability of intravenous (IV) tigecycline in hospitalized subjects of Japanese descent with community-acquired pneumonia (CAP).

NCT ID: NCT00574873 Completed - Clinical trials for Chronic Myeloid Leukemia

Compare Bosutinib To Imatinib In Subjects With Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive CML

Start date: February 5, 2008
Phase: Phase 3
Study type: Interventional

Two-arm, randomized, open-label trial designed to evaluate the efficacy and safety of bosutinib alone compared to imatinib alone in subjects newly diagnosed with chronic phase Chronic Myelogenous Leukemia (CML). The primary endpoint is cytogenetic response rate at one year.

NCT ID: NCT00574795 Completed - Clinical trials for Vaccines, Pneumococcal Conjugate Vaccine

Study Evaluating 13-valent Pneumococcal Conjugate Vaccine in Healthy Japanese Infants

Start date: September 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability, and immunogenicity of the 13-valent pneumococcal conjugate vaccine (13vPnC) in infants of Japanese descent.

NCT ID: NCT00573469 Completed - Crohn's Disease Clinical Trials

Efficacy and Safety Study of D9421-C 9 mg and 15 mg Versus Placebo in Japanese Patients With Active Crohn's Disease

Start date: October 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether treatment with D9421-C for 8 weeks in Japanese patients with mild to moderate active Crohn's disease will improve their symptoms of Crohn's disease and quality of life.