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NCT ID: NCT00235872 Completed - Clinical trials for Rheumatoid Arthritis

Adalimumab in Adult Japanese Subjects With Rheumatoid Arthritis

Start date: August 2004
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess the long-term safety and tolerability of repeated administration of adalimumab in Japanese subjects with rheumatoid arthritis.

NCT ID: NCT00235833 Completed - Clinical trials for Rheumatoid Arthritis

Adalimumab in Adult Japanese Subjects With Rheumatoid Arthritis

Start date: June 2003
Phase: Phase 2
Study type: Interventional

The purpose of the study is to assess the long-term safety, tolerability, and efficacy of repeated administration of adalimumab in adult Japanese subjects with rheumatoid arthritis.

NCT ID: NCT00234104 Completed - Clinical trials for Heart Failure, Congestive

A Dose-finding Study of OPC-41061 in Treatment of Cardiac Edema (Congestive Heart Failure)

Start date: August 2004
Phase: Phase 2
Study type: Interventional

This drug is being developed to treat cardiac edema. The primary purpose of this study is to investigate the dose response for body weight in seven-day repeated oral administration of OPC-41061 at 15, 30, and 45 mg or placebo in patients with extracellular volume expansion secondary to CHF despite taking furosemide at 40 mg/d or more. This study is being conducted in Japan.

NCT ID: NCT00234078 Completed - Dry Eye Syndromes Clinical Trials

Dose-response Study of OPC-12759 Ophthalmic Suspension

Start date: January 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the dose-response of OPC-12759 ophthalmic suspension in dry eye patients.

NCT ID: NCT00234065 Completed - Cerebral Infarction Clinical Trials

Post-marketing Study of Cilostazol (Cilostazol Stroke Prevention Study 2)

Start date: December 2003
Phase: Phase 4
Study type: Interventional

The purpose of this study is to investigate the efficacy of cilostazol in preventing recurrence of cerebral infarction and the safety of long-term administration of the drug (100 mg, twice daily) in patients with cerebral infarction (excluding cardiogenic cerebral embolism) in a multi-center, double-blind, parallel-group comparison with aspirin (81 mg, once daily).

NCT ID: NCT00233870 Completed - Fabry Disease Clinical Trials

A Long Term Safety and Efficacy Study of Fabrazyme Replacement Therapy in Japanese Patients With Fabry Disease.

Start date: June 2004
Phase: Phase 4
Study type: Observational

The purpose of this survey is to identify any concerns regarding the following efficacy and safety-related issues in clinical practice with the new drugs "Fabrazyme for intravenous infusion 5mg" and "Fabrazyme for intravenous infusion 35mg" and to confirm the safety of these products in long-term use in the clinical setting. 1. New adverse drug reactions (ADRs) that cannot be predicted from the Precautions (in particular, clinically significant ADRs) 2. The incidence of ADRs under the actual conditions of use of the drug 3. Causal factors that might potentially affect safety 4. Efficacy evaluation in long-term use This survey will be conducted in accordance with the approval condition established for Fabrazyme: "To conduct a special surveillance of Efficacy and Safety in long term treatment and Pediatric with the drug."

NCT ID: NCT00233441 Completed - Atrial Fibrillation Clinical Trials

Placebo Controlled Double-blind Dose Ranging Study of the Efficacy and Safety of SSR149744C 50, 100, 200 or 300 mg OD With Amiodarone as Calibrator for the Maintenance of Sinus Rhythm in Patients With Recent Atrial Fibrillation/Flutter

MAIA
Start date: December 2004
Phase: Phase 2/Phase 3
Study type: Interventional

Double blind study to evaluate the efficacy and tolerability of SSR149744C and select a dose to be further investigated in the maintenance of sinus rhythm after electrical, pharmacological or spontaneous conversion of AF/AFL.

NCT ID: NCT00233389 Completed - Stomach Ulcer Clinical Trials

Post-marketing Clinical Study of Rebamipide in Patients With Gastric Ulcer

Start date: April 30, 2004
Phase: Phase 4
Study type: Interventional

To examine the efficacy of continued administration of rebamipide following bacteria eradication therapy in patients with H. pylori-positive active gastric ulcer in a placebo-controlled, double-blind study

NCT ID: NCT00233363 Completed - Sjogren's Syndrome Clinical Trials

Exploratory Study for Dry Mouth in Patients With Sjögren's Syndrome

Start date: April 15, 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to exploratively investigate the clinical efficacy of rebamipide on dry mouth in patients with Sjögren's syndrome in comparison with placebo.

NCT ID: NCT00232661 Completed - Breast Cancer Clinical Trials

PROACT - Pre-Operative Arimidex Compared To Tamoxifen

Start date: August 2000
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare tamoxifen, versus a newer treatment, ARIMIDEX, which we already know to be well tolerated. The main objectives of this research study are to see whether using these drugs will shrink down tumours before surgery and to see if any shrinkage in the tumour affects the extent of surgery that is required.