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NCT ID: NCT00280410 Completed - Clinical trials for Lesions of the Liver

Study Investigating the Effect of E7337 on Tumor Like Lesions in Computed Tomography (CT) of the Liver

Start date: February 2006
Phase: Phase 2/Phase 3
Study type: Interventional

This is a multicenter, randomized, open-label study to investigate the superiority of the contrast enhancement effect of E7337 on tumor-like lesions in the Dynamic CT of the liver.

NCT ID: NCT00280397 Completed - Clinical trials for Cancer: Solid Tumors

An Open Label Phase I Dose Escalation Study of E7080 Administered to Patients With Solid Tumors

Start date: January 2006
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the maximum tolerable dose (MTD) and the related effects of E7080 administered to patients with solid tumors that are resistant to approved existing anti-tumor therapies, or for which no appropriate treatment is available.

NCT ID: NCT00280384 Completed - Clinical trials for Spasmodic Torticollis

An Electrophysiological Study Of E2014 In Healthy Adult Male Japanese And Caucasian Subjects

Start date: January 2006
Phase: Phase 2
Study type: Interventional

To evaluate inter-ethnic similarity in pharmacodynamics between Japanese and Caucasian healthy adult male subjects by comparing electrophysiological reactions after administering E2014 to extensor digitorum brevis muscle (EDB).

NCT ID: NCT00276133 Completed - Chronic Nephropathy Clinical Trials

Effects of Atorvastatin Versus Probucol on Small Dense LDL

Start date: January 2004
Phase: Phase 4
Study type: Interventional

Small dense low-density lipoprotein (LDL) plays an important role in causing glomerular injury through conversion to an oxidatively modified form of LDL. However, few studies evaluated the effects of antilipidemic agents on the LDL particle size and renoprotective actions in hyperlipidemic patients with non-diabetic nephropathy.

NCT ID: NCT00270881 Completed - Clinical trials for Acute Lymphoblastic Leukemia

Safety and Efficacy of Unrelated Cord Blood Transplantation for Adult Patients With Hematologic Malignancies

Start date: January 2006
Phase: Phase 1/Phase 2
Study type: Interventional

The primary purpose of this study is to evaluate the safety and efficacy of cord blood transplantation for adult patients with hematologic malignancies including refractory acute leukemia. The transplant procedure was determined in detail according to the previously published report showing a high survival, so that the investigators could expect a similar result.

NCT ID: NCT00269126 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Clinical Evaluation Of GW815SF For Chronic Obstructive Pulmonary Disease (Chronic Bronchitis, Emphysema)

Start date: February 2005
Phase: Phase 3
Study type: Interventional

This study compares the effect of two medicines on COPD (Chronic Obstructive Pulmonary Disease). This study will last up to 18 weeks, and subjects will visit the clinic 5 times. Subjects will be given breathing tests, and will record their breathing symptoms daily on diary cards.

NCT ID: NCT00269087 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

GW815SF For Chronic Obstructive Pulmonary Disease (Chronic Bronchitis, Emphysema)

Start date: January 28, 2005
Phase: Phase 3
Study type: Interventional

This study evaluates the safety of medicine on COPD (Chronic Obstructive Pulmonary Disease). This study will last up to 56 weeks, and subjects will visit the clinic 16 times. Subjects will be given breathing tests, and will record their breathing symptoms daily on diary cards.

NCT ID: NCT00268320 Completed - Clinical trials for Congestive Heart Failure, Atrial Arrhythmia, Atrial Tachyarrhythmia, Atrial Fibrillation

Clinical Investigation of the Medtronic Concertoâ„¢ Device

Start date: January 2006
Phase: N/A
Study type: Interventional

Heart failure is a progressive disease that decreases the pumping action of the heart. This may cause a backup of fluid in the heart and may result in heart beat changes. When there are changes in the heart beat sometimes an implantable heart device is used to control the rate and rhythm of the heart beat. In certain heart failure cases, when the two lower chambers of the heart no longer beat in a coordinated manner, cardiac resynchronization therapy may be prescribed. People who have a dangerously fast heart beat, or whose heart is at risk of stopping beating, may be in need of an electronic device called an implantable cardioverter defibrillator (ICD). Atrial tachyarrhythmia (AT) is the name for rapid beats in the upper chambers of the heart. People with AT may experience symptoms such as heart palpitations (a racing or pounding feeling in the chest), shortness of breath, dizziness, fatigue or weakness. The purpose of this study is to study an investigational implantable device containing Cardiac Resynchronization Therapy (CRT) and Implantable Cardioverter Defibrillator (ICD) therapies (CRT+ICD device) in subjects who are at significant risk of developing atrial tachyarrhythmias.

NCT ID: NCT00266630 Completed - Clinical trials for Manic or Mixed Episode Associated With Bipolar I Disorder

Efficacy and Safety of Olanzapine in the Extended Treatment for Manic or Mixed Episode of Bipolar I Disorder

Start date: November 2005
Phase: Phase 3
Study type: Interventional

The efficacy and safety of the extended treatment to patients with most recent episode manic or mixed who completed previous double blind study (F1D-JE-BMAC [Study BMAC]) will be examined.

NCT ID: NCT00266006 Completed - Clinical trials for Acquired Bleeding Disorder

Factor VIIa in Acute Intracerebral Haemorrhage

Start date: January 2006
Phase: Phase 2
Study type: Interventional

This trial is conducted in Japan. The purpose of this trial is to evaluate the safety and preliminary efficacy of Activated Recombinant Factor VII (NN-007) in patients with acute intracerebral haemorrhage.