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NCT ID: NCT00462956 Completed - Neoplasms, Breast Clinical Trials

GW572016 In Patients With Advanced Or Metastatic Breast Cancer

Start date: June 30, 2004
Phase: Phase 1
Study type: Interventional

This study is designed to evaluate the efficacy and safety of GW572016 in patients with refractory breast cancer and consists of two cohorts of patients. Patients in Cohort A must have ErbB2 overexpressing tumors while patients in Cohort B must have non-ErbB2 overexpressing tumors. Patients eligible for this study must have advanced metastatic breast cancer who have previously received treatment with anthracycline and taxane.

NCT ID: NCT00462670 Completed - Edema, Cardiac Clinical Trials

A Double-blind, Placebo-controlled Study of OPC-41061 in the Treatment of Cardiac Edema (Congestive Heart Failure)

Start date: April 2007
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy and safety of 7-day repeated oral administration of OPC-41061 15 mg or placebo in congestive heart failure (CHF) patients with extracellular volume expansion despite the use of a conventional diuretic.

NCT ID: NCT00461305 Completed - Dysmenorrhea Clinical Trials

Safety Study of Ethinylestradiol/Drospirenone in Dysmenorrhea

Start date: February 2007
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to investigate efficacy of ethinylestradiol for intracyclic bleeding profile in patients with dysmenorrhea and to investigate the long term safety

NCT ID: NCT00460655 Completed - Clinical trials for Cerebrovascular Accident

Study of GSK1358820 In Patients With Post-Stroke Lower Limb Spasticity

Start date: May 2007
Phase: Phase 3
Study type: Interventional

This is a study to confirm the superior efficacy of GSK1358820 over placebo in patients with equinus deformity associated with post-stroke lower limb spasticity using the Modified Ashworth Scale (MAS) ankle score.

NCT ID: NCT00460564 Completed - Clinical trials for Cerebrovascular Accident

Study Of GSK1358820 In Patients With Post-Stroke Upper Limb Spasticity

Start date: May 2007
Phase: Phase 3
Study type: Interventional

This is a study to confirm the superior efficacy of a single treatment of GSK1358820 over placebo in patients with post-stroke upper limb spasticity of both the wrist and finger flexors using the Modified Ashworth Scale (MAS) wrist score.

NCT ID: NCT00460213 Completed - Hypertension Clinical Trials

Valsartan Optimal Therapy Against Elevated Home Blood Pressure Research(VOYAGER)Study

Start date: July 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare improvement percentage of urinary albumin excretion between valsartan 80 mg- and valsartan 160 mg-based therapy in patient with morning hypertension.

NCT ID: NCT00459004 Completed - Obesity Clinical Trials

Japanese Dose-Response Study of Rimonabant in Obese Patients

Start date: October 2004
Phase: Phase 2
Study type: Interventional

The primary objective is to verify the dose-response relationship of rimonabant on body weight change. The secondary objectives are to compare the effect of 3 doses of SR141716 to placebo, on body weight loss and on secondary criteria associated with comorbidities, and to evaluate the safety and the pharmacokinetics of SR141716.

NCT ID: NCT00458328 Completed - Clinical trials for Functioanl Dyspepsia

The Effect of Z-338 in Subjects With Functional Dyspepsia

Start date: April 2007
Phase: Phase 2
Study type: Interventional

Z-338; PhaseIIb, Single-centre, Randomized, Double-blind, Placebo-controlled, Parallel group study in Subjects with Functional Dyspepsia, evaluate the motility of gastro-duodenum by ultrasound

NCT ID: NCT00457743 Completed - Clinical trials for Gastrointestinal Stromal Tumors

A Phase I/II Study of Sunitinib Malate (SU011248) In Patients With Gastrointestinal Stromal Tumor (GIST)

Start date: January 2005
Phase: Phase 1/Phase 2
Study type: Interventional

Phase I;To investigate the clinically recommended dose of Sunitinib malate (SU011248) following multiple oral dosing in the first cycle (4 consecutive weeks and 2 weeks rest) by reviewing the safety and tolerability. Phase II;To determine the objective tumor response and the safety of Sunitinib malate (SU011248) at the clinically recommended dose.

NCT ID: NCT00456859 Completed - Clinical trials for Kidney Failure, Chronic

Carbonaceous Oral Adsorbent's Effects on Progression of Chronic Kidney Disease

CAP-KD
Start date: April 2004
Phase: Phase 4
Study type: Interventional

The CAP-KD trial is a prospective, multicenter, randomized, open-label, two-arm, parallel group comparison clinical trial and will be conducted as a researcher-directed study to assess the efficacy of Kremezin in preventing the progression of CKD. We compare two groups of patients: those receiving conventional treatment alone and those receiving such treatment paired with Kremezin.