Clinical Trials Logo

Filter by:
NCT ID: NCT02386800 Recruiting - Clinical trials for Acute Myeloid Leukemia

CINC424A2X01B Rollover Protocol

Start date: March 5, 2015
Phase: Phase 4
Study type: Interventional

This is a long term safety study for patients that have been treated with either ruxolitinib or a combination of ruxolitinib with panobinostat, on a Novartis or Incyte sponsored study, who have been judged by the study Investigator to benefit from ongoing treatment.

NCT ID: NCT02385994 Completed - Melasma Clinical Trials

A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian Skin

Start date: April 2015
Phase: N/A
Study type: Interventional

The purpose of this investigation is to evaluate safety and efficacy of the Cutera enlighten dual-pulse duration, dual-wavelength 532nm KTP/1064nm Nd:YAG laser for the treatment of melasma and lentigines on the face in Asian skin.

NCT ID: NCT02382939 Completed - Clinical trials for Adult Growth Hormone Deficiency

A Trial to Compare the Safety of Once Weekly Dosing of Somapacitan With Daily Norditropin® FlexPro® for 26 Weeks in Previously Human Growth Hormone Treated Adults With Growth Hormone Deficiency

REAL 2
Start date: February 12, 2015
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe and Asia. The aim of the trial is to compare the safety of once weekly dosing of somapacitan (administered with an investigational pen) with daily Norditropin® FlexPro® (somatropin delivered within a prefilled pen) for 26 weeks in previously human growth hormone (hGH) treated adults with growth hormone deficiency.

NCT ID: NCT02382796 Completed - NSCLC Clinical Trials

A Rollover Protocol of Dacomitinib For Patients In Japan

Start date: July 10, 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study to permit continued access to dacomitinib for patients who participated in other dacomitinib monotherapy treatment protocols in Japan and have the potential to derive clinical benefit without unacceptable toxicity from continued dacomitinib treatment.

NCT ID: NCT02382276 Completed - Alcohol Dependence Clinical Trials

A Long-term Extension Study for the Phase 3 Study of Nalmefene (339-14-001) in Patients With Alcohol Dependence

Start date: July 13, 2015
Phase: Phase 3
Study type: Interventional

The long-term safety and efficacy of nalmefene hydrochloride at 20 mg in patients with alcohol dependence will be evaluated in a multicenter, open-label, uncontrolled trial.

NCT ID: NCT02379793 Completed - Clinical trials for Skin and Connective Tissue Diseases

Skin Irritation Test of LEO 80185 Gel in Healthy Japanese Subjects

Start date: March 2015
Phase: Phase 1
Study type: Interventional

The purpose of the study is to investigate skin irritation of LEO 80185 gel, gel vehicle and Liquid Paraffin in healthy Japanese male subjects.

NCT ID: NCT02379091 Completed - Clinical trials for Rheumatoid Arthritis

Dose Finding Study of Namilumab in Combination With Methotrexate in Participants With Moderate to Severe Rheumatoid Arthritis (RA)

NEXUS
Start date: December 17, 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to establish proof of concept and identify the optimal efficacious dose for namilumab in RA in patients with an inadequate response to methotrexate (MTX-IR) and in patients with an inadequate response to one tumor necrosis factor (TNF)-inhibitor (TNF-IR).

NCT ID: NCT02378688 Completed - Crohn's Disease Clinical Trials

Safety and Efficacy of MT-1303 in Subjects With Moderate to Severe Active Crohn's Disease

Start date: March 2015
Phase: Phase 2
Study type: Interventional

The primary objectives of the study are: - To evaluate the safety and tolerability of MT-1303 in subjects with moderate to severe active Crohn's Disease(CD) - To evaluate the clinical efficacy of MT-1303 in subjects with moderate to severe active CD.

NCT ID: NCT02377752 Completed - Neoplasm Clinical Trials

A Study of Olaratumab in Japanese Participants With Advanced Cancer

Start date: March 23, 2015
Phase: Phase 1
Study type: Interventional

This study consists of 2 parts (Part A and Part B). The main purpose of Part A is to evaluate safety and side effects of olaratumab in combination with doxorubicin in Japanese participants with a group of rare cancers (advanced solid tumors, especially advanced soft tissue sarcoma [STS].) The main purpose of Part B is to evaluate how much olaratumab gets into the blood stream of Japanese participants with advanced solid tumors and how long it takes the body to get rid of it.

NCT ID: NCT02377713 Completed - Alzheimer's Disease Clinical Trials

A Single Dose Study of KHK6640 in Japanese Patients With Alzheimer's Disease.

Start date: March 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of KHK6640, given as a single dose in Japanese patients with Mild to Moderate Alzheimer's Disease.