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NCT ID: NCT02451150 Completed - Clinical trials for Pediatric Hypertension

A Phase 3 Pharmacokinetic Study of TAK-536 in Pediatric Patients 6 to Less Than 16 Years With Hypertension

Start date: August 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetics and safety of a single dose of TAK-536 in pediatric patients aged 6 to less than 16 years with hypertension.

NCT ID: NCT02450903 Completed - Clinical trials for Non-Small-Cell Lung Cancer

LDK378 in Patients With ALK Positive NSCLC Previously Treated With Alectinib.

Start date: August 21, 2015
Phase: Phase 2
Study type: Interventional

This was a single-arm, open-label, multicenter, phase II study to evaluate the efficacy and safety of the ALK inhibitor LDK378 when used as single agent in patients with ALK-rearranged stage IIIB or IV NSCLC previously treated with alectinib. Treatment with LDK378 750 mg qd continued until the patient experienced disease progression as determined by the investigator according to RECIST 1.1, unacceptable toxicity that precluded further treatment, pregnancy, start of a new anticancer therapy, discontinued treatment at the discretion of the patient or investigator, lost to follow-up, death, or study was terminated by Sponsor.

NCT ID: NCT02450799 Completed - Pseudophakia Clinical Trials

Corrected VA With Long-Term Follow-Up After AcrySof® Intraocular Lens (IOL) Implantation

Start date: June 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the long-term VA with an acrylic IOL to a silicone or polymethylmethacrylate (PMMA) IOL in cataract patients. This study will take place in Japan.

NCT ID: NCT02450331 Terminated - Clinical trials for Carcinoma, Transitional Cell

A Study of Atezolizumab Versus Observation as Adjuvant Therapy in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (UC) After Surgical Resection

IMvigor010
Start date: October 5, 2015
Phase: Phase 3
Study type: Interventional

This Phase III, open-label, randomized, multicenter study is to evaluate the efficacy and safety of adjuvant treatment with atezolizumab compared with observation in participants with muscle-invasive UC who are at high risk for recurrence following resection. Eligible participants were randomized by a 1:1 ratio into atezolizumab group or control group.

NCT ID: NCT02449330 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Teneligliptin on the Progressive Left Ventricular Diastolic Dysfunction With Type 2 Diabetes Mellitus Study

TOPLEVEL
Start date: June 2015
Phase: Phase 4
Study type: Interventional

This is the clinical trial designed to assess the cardiac diastolic function of long term treatment with teneligliptin compared to that without teneligliptin in patients with type 2 diabetes mellitus by two arms; one includes patients showing E/e' by echocardiography less than 8, the other includes patients showing E/e' by echocardiography more than 8.

NCT ID: NCT02448784 Completed - Clinical trials for Dementia With Lewy Body Disease

Post-marketing Surveillance of Donepezil Hydrochloride - Investigation of Long Term Safety and Efficacy of Aricept as Well as Its Proper Use Information in Patients With Dementia With Lewy Bodies (DLB).

Start date: April 20, 2015
Phase:
Study type: Observational

To investigate long term safety (especially about Parkinsonism) and efficacy of donepezil hydrochloride in clinical practice as well as its proper use information in participants with DLB.

NCT ID: NCT02448719 Completed - Clinical trials for Healthy Male Adults Participants

Single-Dose Phase 1 Study of TAK-792

Start date: May 27, 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to characterize the safety and tolerability profile of TAK-792 when administered as a single oral dose in healthy Japanese and Caucasian male participants.

NCT ID: NCT02448628 Completed - Hypertension Clinical Trials

A Phase 2 Exploratory Study of CS-3150 in Japanese Hypertensive Patients With Moderate Renal Impairment

Start date: May 2015
Phase: Phase 2
Study type: Interventional

This study is a multi-center, open label, dose titration, exploratory study to evaluate efficacy and safety of CS-3150 in Japanese hypertensive patients with moderate renal impairment. Primary endpoint is change from baseline in sitting systolic and diastolic blood pressure.

NCT ID: NCT02447393 Completed - Dermatitis Clinical Trials

Phase 1 Study of Levocetirizine

Start date: March 18, 2008
Phase: Phase 1
Study type: Interventional

This is a single center, single blind, single dose, randomized, partial cross-over study to confirm bioequivalence between levocetirizine and cetirizine.

NCT ID: NCT02446899 Completed - Clinical trials for Active Systemic Lupus Erythematosus

Efficacy and Safety of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus

Start date: July 9, 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of an intravenous treatment regimen of anifrolumab versus placebo in adult participants with moderately to severely active, autoantibody-positive systemic lupus erythematosus (SLE).