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NCT ID: NCT01014988 Completed - Influenza, Human Clinical Trials

Safety Study to Assess IV Zanamivir for Treatment of Influenza Infection in Patients Who Are in Hospital

Start date: November 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether zanamivir aqueous solution given by intravenous injection is safe in treating hospitalized patients with confirmed influenza infection. A single arm open-label design has been selected to achieve the primary objective of providing regulatory authorities with safety data on IV zanamivir.

NCT ID: NCT01014208 Completed - Clinical trials for Lymphoma, Large-Cell, Diffuse

Ofatumumab Versus Rituximab Salvage Chemoimmunotherapy Followed by Autologous Stem Cell Transplant in Relapsed or Refractory Diffuse Large B Cell Lymphoma

ORCHARRD
Start date: March 2010
Phase: Phase 3
Study type: Interventional

This study is being conducted to compare the efficacy and safety of ofatumumab in addition to salvage chemotherapy versus rituximab in addition to salvage chemotherapy in CD20 positive DLBCL subjects relapsing, or with persistent disease, after first-line treatment with rituximab combined with an anthracycline-based chemotherapy regimen and be eligible for ASCT.

NCT ID: NCT01013974 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

A Study of GSK573719 in Healthy Japanese Male Subjects

Start date: October 5, 2009
Phase: Phase 1
Study type: Interventional

This is a single centre, randomized, double blind, placebo controlled, single and repeat dose study to investigate the safety, tolerability, and pharmacokinetics of inhaled dose of GSK573719 with lactose and containing magnesium stearate by a novel dry powder device in healthy Japanese male subjects.

NCT ID: NCT01012973 Completed - Clinical trials for Retinal Vein Occlusion

Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Central Retinal Vein Occlusion (CRVO)

GALILEO
Start date: October 2009
Phase: Phase 3
Study type: Interventional

To determine the efficacy of vascular endothelial growth factor (VEGF) Trap-Eye injected into the eye on vision function in subjects with macular edema as a consequence of central retinal vein occlusion

NCT ID: NCT01010828 Completed - Clinical trials for Gonarthrosis Patients Who Need Artificial Knee Joint Total Replacement

Review on Minimally Invasive Skin Incision in Vanguard PS Artificial Knee Joint System

Start date: October 1, 2009
Phase: N/A
Study type: Interventional

This study will show whether Tri-Vector method can ensure more extensive visual field and conduct the precise surgery when compared with Mini Mid-Vastus method by conducting 2 types of skin incision approach, Tri-Vector for 36 patients or Mini-Mid Vastus for 36 patients in Vanguard PS artificial knee joint total replacement observational period before and during surgery.

NCT ID: NCT01010763 Completed - Avascular Necrosis Clinical Trials

A Study on M2a Magnum Total Hip Arthroplasty

Start date: November 2009
Phase: N/A
Study type: Interventional

The purpose of this study includes the investigation of Metal-ion release and Renal Function analysis in M2a Total Hip Arthroplasty.

NCT ID: NCT01010022 Completed - Hemorrhage Clinical Trials

Trial of 6% HES130/0.4

Start date: November 2009
Phase: Phase 3
Study type: Interventional

The study shall evaluate the efficacy and safety of two different hydroxyethyl starch solutions (artificial colloids 6% HES130/0.4 and 6% HES70/0.5, Salinhes®) for intra-operative therapy of hypovolemia and maintenance of circulating blood volume in patients undergoing orthopedic surgery. The primary efficacy endpoint will be the required volume of colloid solution infused from start until end of surgery. It is the aim of the clinical trial to demonstrate that comparable volumes of colloid solution are used between treatment groups.

NCT ID: NCT01009658 Completed - Clinical trials for Gastroesophageal Reflux

MSG and Gastrointestinal Motility

Start date: December 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to clarify the physiological function of sodium glutamate by measuring its effect on upper GI motility ( gastric emptying).

NCT ID: NCT01008852 Completed - Clinical trials for Active Rheumatoid Arthritis

Study Evaluating The Efficacy And Safety Of SBI-087 In Seropositive Subjects With Active Rheumatoid Arthritis

Start date: December 2009
Phase: Phase 2
Study type: Interventional

This study is designed to evaluate the safety and efficacy of a dose and dosage regimen of SBI-087 in seropositive patients with active Rheumatoid Arthritis, who are on a stable dose of methotrexate.

NCT ID: NCT01008618 Completed - Chronic Pain Clinical Trials

A Confirmatory Study of Fentanyl in Participants With Osteoarthritis or Low Back Pain

Start date: January 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate efficacy and safety of fentanyl in opioid-naive participants with osteoarthritis (disorder, which is seen mostly in older persons, in which the joints become painful and stuff) or low back pain who cannot obtain a sufficient analgesic effect by the treatment of non-opioid analgesics (drug used to control pain).