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NCT ID: NCT02453555 Completed - Clinical trials for Diabetes Mellitus, Type 2

Empagliflozin Add on to Linagliptin Study in Japanese Patient With Type 2 Diabetes Mellitus

Start date: May 14, 2015
Phase: Phase 3
Study type: Interventional

This trial will compare the use of fixed dose combination of empagliflozin and linagliptin to linagliptin alone in patient with type 2 diabetes mellitus

NCT ID: NCT02453256 Completed - Systemic Sclerosis Clinical Trials

A Study of the Efficacy and Safety of Tocilizumab in Participants With Systemic Sclerosis (SSc)

focuSSced
Start date: November 20, 2015
Phase: Phase 3
Study type: Interventional

This study will assess the efficacy and safety of tocilizumab compared with placebo in participants with SSc across approximately 120 planned global study sites. The study will consist of a 48-week, double-blind, placebo-controlled period followed by a 48-week open-label treatment period. Participants will be assigned, in a 1:1 ratio, to double-blind treatment with active tocilizumab or matching placebo. In the open-label period, eligible participants from either arm may receive active tocilizumab.

NCT ID: NCT02452684 Completed - Insomnia Clinical Trials

Investigation of the Safety and Efficacy of Eszopiclone in Insomnia Patients

Start date: October 1, 2012
Phase:
Study type: Observational

To investigate the safety and efficacy of administration of eszopiclone for 4 weeks in insomnia patients.

NCT ID: NCT02452190 Completed - Asthma Clinical Trials

Study of Reslizumab in Participants With Uncontrolled Asthma and Elevated Blood Eosinophils

Start date: September 28, 2015
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to determine the effect of reslizumab (110 mg) administered subcutaneously every 4 weeks on clinical asthma exacerbations in adults and adolescents with asthma and elevated blood eosinophils who are inadequately controlled on standard-of-care asthma therapy.

NCT ID: NCT02451930 Completed - Clinical trials for Stage IV Non-Small Cell Lung Cancer

A Study of the Combination of Necitumumab (LY3012211) and Pembrolizumab (MK3475) in Participants With NSCLC

Start date: September 4, 2015
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate the safety and efficacy of the combination of necitumumab with pembrolizumab in participants with stage IV non-small cell lung cancer (NSCLC).

NCT ID: NCT02451150 Completed - Clinical trials for Pediatric Hypertension

A Phase 3 Pharmacokinetic Study of TAK-536 in Pediatric Patients 6 to Less Than 16 Years With Hypertension

Start date: August 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetics and safety of a single dose of TAK-536 in pediatric patients aged 6 to less than 16 years with hypertension.

NCT ID: NCT02450903 Completed - Clinical trials for Non-Small-Cell Lung Cancer

LDK378 in Patients With ALK Positive NSCLC Previously Treated With Alectinib.

Start date: August 21, 2015
Phase: Phase 2
Study type: Interventional

This was a single-arm, open-label, multicenter, phase II study to evaluate the efficacy and safety of the ALK inhibitor LDK378 when used as single agent in patients with ALK-rearranged stage IIIB or IV NSCLC previously treated with alectinib. Treatment with LDK378 750 mg qd continued until the patient experienced disease progression as determined by the investigator according to RECIST 1.1, unacceptable toxicity that precluded further treatment, pregnancy, start of a new anticancer therapy, discontinued treatment at the discretion of the patient or investigator, lost to follow-up, death, or study was terminated by Sponsor.

NCT ID: NCT02450799 Completed - Pseudophakia Clinical Trials

Corrected VA With Long-Term Follow-Up After AcrySof® Intraocular Lens (IOL) Implantation

Start date: June 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the long-term VA with an acrylic IOL to a silicone or polymethylmethacrylate (PMMA) IOL in cataract patients. This study will take place in Japan.

NCT ID: NCT02448784 Completed - Clinical trials for Dementia With Lewy Body Disease

Post-marketing Surveillance of Donepezil Hydrochloride - Investigation of Long Term Safety and Efficacy of Aricept as Well as Its Proper Use Information in Patients With Dementia With Lewy Bodies (DLB).

Start date: April 20, 2015
Phase:
Study type: Observational

To investigate long term safety (especially about Parkinsonism) and efficacy of donepezil hydrochloride in clinical practice as well as its proper use information in participants with DLB.

NCT ID: NCT02448719 Completed - Clinical trials for Healthy Male Adults Participants

Single-Dose Phase 1 Study of TAK-792

Start date: May 27, 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to characterize the safety and tolerability profile of TAK-792 when administered as a single oral dose in healthy Japanese and Caucasian male participants.