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NCT ID: NCT02543463 Completed - Clinical trials for Degenerative Joint Disease

Navigation With X3 vs Non-Navigation With X3 Study

Start date: April 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effect of the large head in THA with a navigation system and without a navigation system.

NCT ID: NCT02541942 Completed - Clinical trials for Congenital Bleeding Disorder

Pharmacogenetic Testing of Saliva Samples From Patients With Five or More Exposure Days to rFVIIa Analogue in the Adept™2 Trial

Start date: April 3, 2015
Phase: Phase 2
Study type: Interventional

This study is conducted globally. This study describes pharmacogenetic testing of saliva samples from patients who participated in the NN1731-3562 trial (adept™2) (NCT01392547). The objective is to determine the HLA (human leukocyte antigen) type and polymorphisms in the FVII gene in patients previously exposed to rFVIIa analogue.

NCT ID: NCT02541084 Completed - Clinical trials for Wet Macular Degeneration

Caregiver Burden of Wet Age-related Macular Degeneration (wAMD) in Japan

Start date: August 18, 2015
Phase: N/A
Study type: Observational

This study aims at investigation of the caregiver burden of Wet Age-related Macular Degeneration (wAMD) patients and at the assessment of how much of caregiver burden could be reduced in transitioning from Pro Re Nata to proactive therapy especially in real-life rural settings where public transportations are not readily available.

NCT ID: NCT02540993 Completed - Clinical trials for Chronic Kidney Disease

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease

FIDELIO-DKD
Start date: September 17, 2015
Phase: Phase 3
Study type: Interventional

The primary objective of this study was to demonstrate whether, in addition to standard of care, finerenone is superior to placebo in delaying the progression of kidney disease, as measured by the composite endpoint of time to first occurrence of kidney failure, a sustained decrease of estimated glomerular filtration rate (eGFR) ≥40% from baseline over at least 4 weeks, or renal death.

NCT ID: NCT02540967 Completed - Clinical trials for Magnetic Resonance Imaging

Drug Use Investigation of Gadovist.

Start date: October 27, 2015
Phase:
Study type: Observational

The objectives of this study are to investigate the safety and effectiveness of Gadovist.

NCT ID: NCT02539225 Completed - Clinical trials for Gastroesophageal Junction Adenocarcinoma

A Study of Ramucirumab in Participants With Gastric or Gastroesophageal Junction Adenocarcinoma

Start date: October 5, 2015
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to evaluate the effectiveness of S-1 and oxaliplatin with or without ramucirumab as first line therapy in participants with metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma.

NCT ID: NCT02538666 Completed - Lung Cancer Clinical Trials

An Investigational Immuno-therapy Study of Nivolumab, or Nivolumab in Combination With Ipilimumab, or Placebo in Patients With Extensive-Stage Disease Small Cell Lung Cancer (ED-SCLC) After Completion of Platinum-based Chemotherapy

CheckMate 451
Start date: October 13, 2015
Phase: Phase 3
Study type: Interventional

In this study, all patients must have already completed first-line chemotherapy to treat extensive-stage disease small cell lung cancer. The purpose of this study is to show that nivolumab, or nivolumab plus ipilimumab followed by nivolumab by itself, will prolong overall survival when administered as consolidation treatment in patients that are stable or responding after chemotherapy. Patients receiving treatment will be compared with patients taking placebo.

NCT ID: NCT02537834 Completed - Clinical trials for Type 2 Diabetes Mellitus

Tofogliflozin GLP-1 Analogue Combination Trial

Start date: August 2015
Phase: Phase 4
Study type: Interventional

An open-label, multicenter study to evaluate 52-week long-term safety, tolerability and efficacy of Tofogliflozin with GLP-1 analogue treatment in type 2 diabetes mellitus.

NCT ID: NCT02537730 Completed - Myopia Clinical Trials

BIOCLEAN MPS (Multi-Purpose Solution) VII in Combination With Biofinity Lens: A Two Week Crossover Study

Start date: September 2015
Phase: N/A
Study type: Interventional

Two week, Open Label, randomized, bilateral, crossover, 1 week of daily wear in each combination (lens / disinfecting cleaning system).

NCT ID: NCT02537457 Completed - Clinical trials for Embolism, Atrial Fibrillation and Venous Thrombosis

Bioequivalence Study of Rivaroxaban

Start date: January 2014
Phase: Phase 1
Study type: Interventional

The objectives of this study are to establish the bioequivalence between rivaroxaban tablet 15 mg and rivaroxaban granule formulation 15 mg, and to assess the safety and tolerability of rivaroxaban 15 mg in healthy adult male subjects.