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NCT ID: NCT02959944 Completed - Clinical trials for Chronic Graft Versus Host Disease

Ibrutinib in Combination With Corticosteroids vs Placebo in Combination With Corticosteroids in Participants With New Onset Chronic Graft Versus Host Disease (cGVHD)

iNTEGRATE
Start date: May 11, 2017
Phase: Phase 3
Study type: Interventional

To evaluate the safety and efficacy of ibrutinib in combination with prednisone in subjects with newly diagnosed moderate to severe cGVHD.

NCT ID: NCT02959814 Completed - Clinical trials for Coronary Artery Disease

Diagnostic Accuracy of On-line Quantitative Flow Ratio (QFR). FAVOR II Europe-Japan

FAVOR II EJ
Start date: February 22, 2017
Phase:
Study type: Observational

Quantitative Flow Ratio (QFR) is a novel method for evaluating the functional significance of coronary stenosis. QFR is assessed by calculation of the pressure in the vessel based on two angiographic projections. The purpose of the FAVOR II study is to evaluate the diagnostic accuracy of on-line QFR compared to 2D Quantitative Coronary Angiography (QCA) with FFR as gold standard.

NCT ID: NCT02959190 Completed - Migraine Clinical Trials

A Study of LY2951742 (Galcanezumab) in Japanese Participants With Migraine

Start date: February 7, 2017
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to evaluate the safety and effectiveness of the study drug known as Galcanezumab in Japanese participants with migraine.

NCT ID: NCT02959177 Completed - Migraine Clinical Trials

A Study of LY2951742 (Galcanezumab) in Japanese Participants With Episodic Migraine

Start date: November 9, 2016
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to determine the efficacy of the study drug Galcanezumab in Japanese participants with episodic migraine.

NCT ID: NCT02957682 Completed - Clinical trials for Hypercholesterolemia

Evaluating Effect of the Study Drug Praluent (Alirocumab) on Neurocognitive Function When Compared to Placebo

Start date: November 2, 2016
Phase: Phase 4
Study type: Interventional

The main purpose of this study is to evaluate the effect on mental state (known as "neurocognitive function") with use of Praluent.

NCT ID: NCT02955589 Completed - Clinical trials for Adult T-Cell Lymphoma (ATL)

Efficacy and Safety of Oral HBI-8000 in Patients With Relapsed or Refractory Adult T Cell Lymphoma (ATL)

Start date: November 2016
Phase: Phase 2
Study type: Interventional

Phase 2b, open-label, non-randomized, single arm study to evaluate the safety, and efficacy of HBI-8000 40 mg BIW in patients with relapsed or refractory ATL (R/R ATL)

NCT ID: NCT02955069 Completed - Clinical trials for Well-differentiated Non-functional NET of Gastrointestinal Origin

Study of Efficacy and Safety of PDR001 in Patients With Advanced or Metastatic, Well-differentiated, Non-functional Neuroendocrine Tumors of Pancreatic, Gastrointestinal (GI), or Thoracic Origin or Poorly-differentiated Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC)

Start date: February 14, 2017
Phase: Phase 2
Study type: Interventional

This study aimed to investigate the efficacy and safety of PDR001 in patients with advanced or metastatic, well-differentiated, non-functional neuroendocrine tumors of pancreatic, gastrointestinal (GI), or thoracic origin or poorly-differentiated gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC) that progressed on prior treatment.

NCT ID: NCT02955030 Completed - Influenza Clinical Trials

Evaluation of the Safety and Immunogenicity of a Sublingual Influenza Vaccine NSV0001 in Healthy Male Volunteers

Start date: October 2016
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and immunogenicity of a sublingual administration of NSV0001 in healthy male volunteers.

NCT ID: NCT02954848 Completed - Clinical trials for Non-erosive Gastroesophageal Reflux Disease

Phase 3 Study of TAK-438 10 mg in the Treatment of Non-Erosive Gastroesophageal Reflux Disease (NERD)

Start date: November 15, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the efficacy and safety of oral TAK-438 10 mg once-daily in the treatment of non-erosive gastroesophageal reflux disease (NERD).

NCT ID: NCT02953938 Completed - Clinical trials for Macular Edema Secondary to Branch Retinal Vein Occlusion (BRVO)

Study to Show a Superior Benefit in Terms of Reduction of Ranibizumab Injections in Patients Receiving Ranibizumab Plus Laser Photocoagulation Combination Therapy Without Loss of Efficacy and Safety

ZIPANGU
Start date: December 15, 2016
Phase: Phase 4
Study type: Interventional

This is a Phase IV, randomized, open-label, active-controlled, 2-arm, multicenter study. The primary objective was assessed by the difference in the mean number of ranibizumab injections applied up to Month 11 between the 2 treatment arms. Patients were randomized in a 1:1 ratio to 1 of the 2 treatment arms; i.e. Arm 1 ranibizumab monotherapy, Arm 2 ranibizumab with Grid&Direct short pulse laser photocoagulation combination therapy. There were 3 periods in this study: Screening Period (visit 1), Treatment Period (visit 2 to Visit 13) and Follow-up Period (visit 14). In addition to screening and Baseline (visit 2), there were monthly visits from Month 1 to Month 12. This study included male and female patients (≥20 years old) diagnosed with visual impairment due to ME secondary to BRVO.