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NCT ID: NCT02757430 Completed - Cardiac Arrhythmias Clinical Trials

EnSite Precision™ 2.0 Registry

Start date: August 30, 2016
Phase:
Study type: Observational [Patient Registry]

The objective of this registry is to assess and characterize the use and performance of the EnSite Precision™ Cardiac Mapping System and the EnSite Precision™ Software V2.0 in a variety of electrophysiological (EP) procedures and clinical settings. This registry will assess the clinical performance of the system in a controlled, real-world environment after commercial release. Up to 500 subjects will be enrolled in up to 50 sites worldwide. Data will be collected at enrollment/baseline, procedure and pre-discharge. There is no long-term follow-up required for this registry. The anticipated registry enrollment is about 6-7 months.

NCT ID: NCT02757209 Completed - Asthma Clinical Trials

Comparative Study on Usability of Inhaler Devices in Adults With Asthma or COPD

PMC-101-APT
Start date: April 2016
Phase: N/A
Study type: Interventional

This is a randomized, multi-center, active-controlled, repeated measures design study in male and female patients 60 years of age and older with persistent asthma or COPD. Study will be conducted in 4 Italian University/Hospital Centers: Ferrara, Parma, Cassano delle Murge (Ba), Tradate. The primary efficacy parameter of the study is inhaler device usability (expressed as total number of repeated attempts required to achieve optimal use).

NCT ID: NCT02756845 Completed - Clinical trials for Advanced Non CNS Tumors

Study of Talimogene Laherparepvec In Children With Advanced Non CNS Tumors

Start date: August 16, 2017
Phase: Phase 1
Study type: Interventional

This is a phase 1 study to evaluate the safety of intralesional talimogene laherparepvec administration in pediatric subjects with advanced non-CNS tumors that are amenable to direct injection

NCT ID: NCT02756676 Completed - Parkinson Disease Clinical Trials

Impact of Rehabilitation in Quality of Life in PD

Start date: April 2015
Phase: N/A
Study type: Interventional

This study is aimed to evaluate the impact of an intensive, multidisciplinary rehabilitative program on quality of life in patients with Parkinson's Disease.

NCT ID: NCT02756611 Completed - Clinical trials for Chronic Lymphocytic Leukemia

A Study to Evaluate the Efficacy of Venetoclax Monotherapy in Relapsed/Refractory Participants With Chronic Lymphocytic Leukemia (CLL)

VENICE I
Start date: June 22, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of venetoclax monotherapy in participants with relapsed/refractory CLL with or without the 17p deletion or TP53 mutation, including those who have received prior treatment with a B-cell receptor inhibitor.

NCT ID: NCT02755597 Completed - Clinical trials for Relapsed/Refractory Multiple Myeloma

A Study Evaluating Venetoclax (ABT-199) in Multiple Myeloma Subjects Who Are Receiving Bortezomib and Dexamethasone as Standard Therapy

Bellini
Start date: July 11, 2016
Phase: Phase 3
Study type: Interventional

This was a Phase 3, multicenter, randomized, double blind, placebo-controlled study evaluating the efficacy and safety of venetoclax plus bortezomib and dexamethasone in participants with relapsed or refractory multiple myeloma who are considered sensitive or naïve to proteasome inhibitors and received 1 to 3 prior lines of therapy for multiple myeloma.

NCT ID: NCT02754141 Completed - Clinical trials for Malignant Solid Tumor

An Investigational Immuno-therapy Study of Experimental Medication BMS-986179 Given Alone and in Combination With Nivolumab

Start date: June 21, 2016
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and tumor-shrinking ability of experimental medication BMS-986179 alone and when combined with Nivolumab, in patients with solid cancers that are advanced or have spread.

NCT ID: NCT02753699 Completed - Clinical trials for Hepatitis C, Chronic

Long Term Follow-up Study to Assess Durability of Sustained Virologic Response in Alisporivir-treated Hepatitis C Patients

Start date: December 2011
Phase: Phase 3
Study type: Interventional

Follow-up for durability of sustained virologic response, changes in liver function and safety in patients with SVR24 in feeder studies

NCT ID: NCT02753127 Completed - Colorectal Cancer Clinical Trials

A Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal Cancer

CanStem303C
Start date: June 2016
Phase: Phase 3
Study type: Interventional

This is an international multi-center, prospective, open-label, randomized, adaptive design phase 3 trial of the cancer stem cell pathway inhibitor napabucasin plus standard bi-weekly FOLFIRI versus standard bi-weekly FOLFIRI in patients with previously treated metastatic colorectal cancer (CRC).

NCT ID: NCT02752776 Completed - Plaque Psoriasis Clinical Trials

A Study to Evaluate Clear Skin Effect on Quality of Life in Patients With Plaque Psoriasis.

PROSE
Start date: March 17, 2016
Phase: Phase 4
Study type: Interventional

Study of effects of secukinumab 300 mg s.c. on quality of life (QoL) in psoriasis in patients with or without prior exposure to systemic therapy.