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NCT ID: NCT05391386 Recruiting - Molar Tube Bonding Clinical Trials

Evaluation of Failure Rate of Molar Tube With a Modified Bonding Technique

Start date: January 15, 2022
Phase: N/A
Study type: Interventional

Comparing between the failure rates of molar tubes bonded with conventional bonding technique using resin adhesive and the alternative bonding technique using compomer (containing glass ionomer) adhesive by adding a layer of compomer adhesive at the molar/tube interface.

NCT ID: NCT05390996 Active, not recruiting - Clinical trials for Dental Implant Stability

Implant Stability Changes In Dental Implants Installed By Osseodensification and Conventional Methods

Start date: January 5, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of Osseodensification on implant stability during the healing period The objective of this study is to compare between dental implant stability after osteotomy site preparation using osseodensification technique and conventional drilling technique immediately after implant installation (primary stability) , 6 week after the insertion of implant and 12 weeks later (secondary stability)

NCT ID: NCT05389059 Enrolling by invitation - Gingival Diseases Clinical Trials

Injectable Platelet Rich Fibrin With Collagen Matrix in Treatment of Multiple Gingival Recession.

Start date: April 25, 2022
Phase: N/A
Study type: Interventional

This study is proposing the use of i-PRF clot as a scaffold for the XCM in order to obtain a novel biomaterial, incorporating active growth factors and collagen matrix in a single framework, based on the potential effect of i-PRF to enhance fibroblast activity and angiogenesis stimulation for treatment of multiple gingival recession.

NCT ID: NCT05379049 Recruiting - Clinical trials for Rheumatoid Arthritis

Therapeutic Response to Tumor Necrosis Factor-alpha (TNF-alpha) Antagonists in Rheumatoid Arthritis.

TNF-alpha
Start date: March 1, 2022
Phase:
Study type: Observational

Rheumatoid arthritis (RA) is an autoimmune, chronic inflammatory disease and TNF-alpha has been recognized as a triggering cytokine in the induction of joints inflammation and is involved in the pathogenesis of RA. Treatment for RA aims to reduce disease activity, prevent or manage joint deterioration and lower the risk of major comorbidities such as heart disease and stroke. The strategy of targeting cytokines has significantly increased RA patient outcomes. Therefore management with biological disease-modifying antirheumatic drugs "bDMARD" (Etanercept, Infliximab, Adalimumab) should be considered, If the treatment goal is not met with the first conventional synthetic drug modifying antirheumatic drugs (csDMARD) strategy, or if there are poor prognostic factors. The multi-biomarker disease activity test could be used to help standardise individual treatment decisions, especially in patients who failed to respond well to the traditional treatment. Iraq does not currently have specific guidelines, which might pose a risk to patients' safety. More data about the choice of bDMARD is needed in terms of tracking therapeutic response, or whether TNF or other pro-inflammatory cytokines like interleukin-6 (IL-6) is the main factor for the development and severity of RA. These data are important to improve the overall status of the patient, better choice of treatment and biomarkers to detect. There is limited information on the treatment patterns of rheumatoid arthritis (RA) across Iraq including the Kurdistan Region. Therefore, the aim of this research is to evaluate the efficacy, and clinical responses of RA patients who have been treated with different anti-TNF, as well as on answering the research hypothesis, Can plasma TNF-alpha and IL-6 be used as markers of therapeutic response to TNF alpha antagonist in patients with RA?

NCT ID: NCT05371691 Recruiting - Clinical trials for Tooth Position Anomalies

A Comparison of the Effectiveness of Two Types of Myofunctional Appliances

Start date: September 10, 2021
Phase: N/A
Study type: Interventional

A randomized clinical trial is set out to compare the effectiveness of two types of functional appliances in the correction of a Class II malocclusion. (Class II malocclusions are where upper front teeth bite significantly further forward in relation to lower front teeth).

NCT ID: NCT05361863 Recruiting - Clinical trials for Treating Class II Malocclusion and Bimaxillary Proclination

Canine Retraction Using Different Bracket Slots' Sizes

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Primary Objective Evaluating the effectiveness of canine retraction in terms of: rate of movement and rotation using 0.020-inch slot and dual-slot systems in comparison with the 0.022-inch slot system. Secondary Objectives - Measuring the amount of molar anchorage loss during canine retraction between the different bracket slot appliances. - Evaluation of alignment efficiency using different bracket slot appliances. Null Hypothesis There is insignificant difference in the effectiveness of canine retraction with different bracket slot size appliances. • Evaluation of the bracket slot and archwire dimensions precision

NCT ID: NCT05345379 Recruiting - Dental Bonding Clinical Trials

A Clinical Comparison of the Effectiveness of Two Moisture Insensitive Primers on Orthodontic Attachment Bond

Start date: April 11, 2022
Phase: N/A
Study type: Interventional

A single-operator, randomized controlled trial (RCT) will be conducted to evaluate the clinical effectiveness of moisture insensitive primers (MIPs) in bonding molar tubes under moisture contaminated conditions by comparing the clinical bond failure and survival rate of molar tubes using two MIPs which are Transbond ™ MIP (3M Unitek Dental Products, Monrovia, CA, USA) and Assure® Plus-All Surface Light Cure Bonding Primer (Reliance, Itasca, IL, USA).

NCT ID: NCT05340959 Completed - Clinical trials for Edentulous Alveolar Ridge

Evaluating Implant Stability Using Three Devices Osstell®, Periotest® and AnyCheck®

Start date: December 15, 2021
Phase:
Study type: Observational

A prospective observational study guided by the guidelines of Strengthening The Reporting Of Observational Study in Epidemiology (STROBE) in 2014, that will be conducted to evaluate implant stability using three devices; Osstell®, Peiotest® and AnyCheck® and comparing the results.

NCT ID: NCT05331820 Completed - Patient Compliance Clinical Trials

The Influence of Weekly Reminders on Enhancing Patient Compliance in Patients With Fixed Orthodontic Treatment

Start date: November 28, 2021
Phase: N/A
Study type: Interventional

this study is a randomized clinical trial to evaluate the effect of sending weekly reminders to patients undergoing fixed orthodontic appliance treatment. two groups will be formed and participants of the study will be divided between the two groups randomly. the intervention group will receive weekly reminders about the importance of oral hygiene and appliance care with adherence to scheduled appointments. the difference between these parameters will be evaluated between the control and intervention groups to describe the importance of weekly reminders to enhance the compliance and cooperation of the patient. the oral hygiene of the patient will include plaque level(plaque index), gingival statue level( bleeding index), and white spot lesion . appliance care will be recorded when in case of bracket failure and appointments missed will also be recorded .

NCT ID: NCT05324761 Completed - Clinical trials for Failed Back Surgery Syndrome

Management of Pain Associated With Failed Back Surgery Syndrome

Start date: April 25, 2022
Phase: Phase 4
Study type: Interventional

Neuropathic pain is a common complication following different types of spine surgery making negative impact on health, along with life style changes and management, many neurologist prescribed either Pregabalin or Gabapentin to manage this condition with overall good results. our study aims to evaluate the efficacy of Pregabalin and Gabapentin in the management of this condition and to compare between them