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NCT ID: NCT06099860 Completed - Clinical trials for Sacroiliac Joint Dysfunction

Therapeutic Impact of KT Along With BT in Patients With Chronic Low Back Pain of Sacroiliac Joint Dysfunction

Start date: November 14, 2022
Phase: N/A
Study type: Interventional

This research aimed to determine the impacts of KT and balance exercises in patients with CLBP of SIJ dysfunction.

NCT ID: NCT06088446 Completed - Clinical trials for Pulpitis - Irreversible

Effect of Intrapulpal Injections on the Post-endodontic Pain

Start date: July 5, 2023
Phase: N/A
Study type: Interventional

To achieve painless treatment in patients with a failed primary IANB, supplementary anesthesia has been advised. The majority of the studies evaluating intrapulpal injections have been performed on asymptomatic teeth. Very limited research has been dedicated to the evaluation of different variables in intrapulpal injections in patients with symptomatic irreversible pulpitis. The aim of this study was to evaluate postoperative pain after an intrapulpal anesthesia injection given after a failed inferior alveolar nerve block (IANB), in patients with symptomatic irreversible pulpitis. This prospective, randomized, double-blind clinical trial was carried out at the Department of Conservative Dentistry and Endodontics, Faculty of Dentistry, Jamia Millia Islamia. One hundred and eight adult patients, with symptomatic irreversible pulpits in a mandibular first or second molar received an initial IANB with 2% lidocaine. Pain during the endodontic treatment was assessed using a visual analog scale (VAS). Patients experiencing pain on endodontic intervention were randomly allocated to one of the two treatment groups: one group received a supplementary intrapulpal injection while the other received a supplementary intraligamentary injection The presence of postoperative pain was assessed at 1, 2, 3, and 7 days after treatment.

NCT ID: NCT06084663 Completed - Clinical trials for Psoriasis and Psoriatic Arthritis

Bioequivalence Study of Two Products of Apremilast 30 mg Tablets in Healthy, Adult, Human Subjects

Start date: February 15, 2023
Phase: Phase 3
Study type: Interventional

An open label, balanced, randomized, two-sequence, two-treatment, two-period, single oral dose, crossover, bioequivalence study in normal, healthy, adult, human subjects under fasting condition

NCT ID: NCT06062459 Completed - Clinical trials for Sacroiliac Joint Dysfunction

Synergistic Benefits of MCE and BT in Sacroiliac Joint Dysfunction: A Randomized Controlled Trial

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

This research aimed to ascertain the combined and individual efficacies of MCE and BT in alleviating SIJD symptoms.

NCT ID: NCT06055582 Completed - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

To Study the Effects of Mango Ingestion in T2DM and Non-diabetic Subjects.

Start date: February 11, 2022
Phase: N/A
Study type: Interventional

T2DM patient will be recruited from endocrine OPD 1. Clinical History and Examination: 1. General Physical Examination: - Height (cm) - weight (kg) - BMI (kg/m2) - Blood Pressure (mmHg) 2. Anthropometry: Circumferences and skinfold thickness will be recorded for the patients in the following manner. Circumferences: - Waist circumference (cm) - Hip circumference (cm) - Mid-arm circumference (cm) - Mid-thigh circumference (cm) 3. Skin fold thickness: Skin fold thickness will be measured by using (LANGE skin fold calipers) (to nearest of 1 mm) at the following sites - Biceps (mm) - Triceps (mm) - Thigh (mm) - Calf (mm) - Sub scapular (mm) - Supra-iliac (mm) - Anterior axillary fold. (mm) 2. Biochemical Test: The biochemical analysis will be done using ELISA kit or commercially available kits - Blood glucose (mg/dL) - HbA1c (%) - Serum insulin (μIU/mL) - Total Cholestrol (mg/dl) - Triglyceride (mg/dl) - Fructosamine (umol/L) - Adiponectin (µg/ml) -- HOMA-IR 3. Body Composition Analysis (TANITA)

NCT ID: NCT06043297 Completed - Antithrombic Drug Clinical Trials

Bioequivalence Study of Two Products of Apixaban 5mg Tablets in Healthy, Adult, Human Subjects

Start date: February 23, 2023
Phase: Phase 1
Study type: Interventional

To compare the bioavailability and characterize the pharmacokinetic profile of the sponsor's test product relative to that of reference product after single oral dose administration in normal, healthy, adult, human subjects under fasting condition and to assess the bioequivalence.

NCT ID: NCT06026475 Completed - Fluid Loss Clinical Trials

Role of Goal Directed Fluid Therapy in Enhanced Recovery After Surgery in Gastro-intestinal Oncosurgeries

GDFT ERAS
Start date: July 13, 2023
Phase: N/A
Study type: Interventional

Enhanced recovery after surgery (ERAS) protocols are multimodal perioperative care pathways designed to achieve early recovery and reducing postoperative morbidity after surgical procedures by maintaining preoperative organ function and reducing the profound stress response following surgery .The key elements of ERAS protocols include preoperative counselling, optimization of nutrition, standardized analgesic and anesthetic regimens , goal directed fluid therapy early mobilization.

NCT ID: NCT05999890 Completed - Lower Limb Fracture Clinical Trials

Comparison of Postoperative Analgesia Between Intravenous Paracetamol and Intranasal Tapentadol

Start date: July 5, 2021
Phase: Phase 4
Study type: Interventional

The aim of the study was to compare the analgesic efficacy of intranasal tapentadol nasal spray 44.5mg and intravenous paracetamol 1gm during the postoperative period by Visual analog scale(VAS)in patients undergoing lower limb(long bone fractures)orthopedic surgeries. Paracetamol is one of the most frequently used analgesic and antipyretic agents, interferes neither with platelet nor kidney functions nor does it present the unwanted side effects of NSAIDs. Tapentadol is a novel, centrally-acting analgesic with a dual mechanism of action, combining mu-opioid receptor agonism with norepinephrine reuptake inhibition. This dual mode of action is responsible for its opioid-sparing effect, which contributes to a reduction in some of the typical opioid-related adverse effects

NCT ID: NCT05996315 Completed - Clinical trials for Adults >18 Years With Distal End Radius Fracture Requiring Closed Reduction in Emergency Department

Ultrasound Guided Supracondylar Nerve Block & Hematoma Block for Closed Reduction of Distal End Radius Fractures

Start date: September 15, 2022
Phase:
Study type: Observational

Comparison of analgesia between ultrasound guided supracondylar radial nerve block and hematoma block for closed reduction of distal end radius fractures- an observational study

NCT ID: NCT05994820 Completed - Vaccine Hesitancy Clinical Trials

Chatbot-based Intervention to Promote Vaccine Acceptance in Varansi, India

Start date: September 26, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn compare the efficacy Chatbot messaging directed to parents of infants and children living in unstable urban housing (UUH) in Varansi, India. The main questions it aims to answer are: 1) Can a Chatbot intervention be used to improve attitudes towards childhood vaccines? 2) Does an intervention in which vaccination is presented in the larger context of well-being improve attitudes towards vaccination?