There are about 9745 clinical studies being (or have been) conducted in Israel. The country of the clinical trial is determined by the location of where the clinical research is being studied. Most studies are often held in multiple locations & countries.
The incidence of secondary cancer (SC) in patients with myeloproliferative neoplasms (MPN) is high and comparable to that of thrombosis. However, the identification of patient subgroups that might be at increased susceptibility of developing SC has not been systematically addressed. This international case-control study (MPN-K) is aimed to elucidate the prognostic role of JAK2V617F mutation in predicting the occurrence of SC in patients with classical MPN, polycythemia vera (PV), essential thrombocythemia (ET) and myelofibrosis (MF)
The aim of the study is to test whether the distal radius bone marrow show significant difference in the fat fraction in young women compared to post menopausal women with and without osteoporosis.
The purpose of the study is to assess the efficacy and safety of 4 doses of cenerimod versus placebo in adult subjects with systemic lupus erythematosus (SLE).
This study will collect data on bleeds and data related to quality of life in people with severe congenital (a disease existing from birth) haemophilia A and B, with or without inhibitors. The aim for the study is to look at the number of bleeds when on usual treatment for haemophilia. Participants will be asked to keep an electronic diary to track the number of bleeds and the treatment of their bleeds. Participants will be asked to wear an activity tracker on their wrist to capture their level of activity every day for up to 12 weeks. While taking part in this study, participants will keep getting their usual treatment as given to them by their doctor. All study visits at the clinic are done in the same way as the participants are used to. In the time between the participants' visits to the clinic, the study staff at the clinic may call or email the participant. The study will last for about 2½ years.
The reason for this study is to compare the study drug LY900014 to insulin lispro (Humalog) in children and adolescents with type 1 diabetes (T1D).
This study will evaluate upadacitinib compared to dupilumab (Dupixent®) in adults with moderate to severe atopic dermatitis (AD) who are candidates for systemic therapy.
The primary objective of this study was to assess the efficacy of rilonacept treatment in participants with recurrent pericarditis.
Background: Food practices are socially, culturally and historically embedded in everyday life. It is a common notion that people eat due to internal state of physiologic hunger but in fact the drive behind eating behaviors is much more complex. We eat, inter alia, because of our response to external cues such as the sight and smell of food, or external eating. Another related concept is food cravings: intense irresistible desires to consume a particular food that is distinct from hunger. Both external eating and food cravings have been associated with impulsivity, eating disorders and obesity. During recent decades the role of the media, and recently of the social media in our lives has grown significantly, and their influence on culture and society is now huge. A common activities on social media sites (SNS) is food viewing and posting pictures of tempting food, known as food porn. Food porn has been found to correlate with eating patterns and food-related attention and reward bias. The aim of this study is to conduct a controlled manipulation that may help us deduce causality as well as association. The investigators postulate that (1) viewing pictures of appetizing food will lead to higher rates of reported external eating and food craving than viewing pictures that are not food related; (2) Viewing these appetizing food pictures will lead participants to order different kinds of food and greater amounts; (3) The effect of viewing food pictures on external eating, food cravings and food orders will be greater for participants with high disturbed eating, then for participants without disturbed eating. Method: After providing informed consent, 150 female participants (aged 18-35) will self report on demographic variables, SNS food preoccupation and disturbed eating (EAT-26). They will then be randomly assigned to watch either a food porn or control video. They will complete measures of food cravings (FCQ-S) and external eating (DEBQ) after watching the video and asked to order food they would like to eat from a virtual menu.)
The purpose of the trial is to assess the efficacy and safety of tirzepatide taken once a week to insulin glargine taken once daily in participants with type 2 diabetes and increased cardiovascular risk. The study will last about 108 weeks and may include up to 30 visits.
This is a randomized controlled trial, planned to study the effects of pedometers (digital step counters) on patient mobility following cesarean delivery. The investigators plan to randomize patients at high risk for thromboembolic events to participants with a personalized repeated feedback approach based on pedometer results, versus participants with no feedback to pedometer results.