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NCT ID: NCT02654171 Completed - Clinical trials for RESPIRATORY SYNCYTIAL VIRUS INFECTIONS

Viral Inhibition in Children for Treatment of RSV

VICTOR
Start date: May 27, 2016
Phase: Phase 2
Study type: Interventional

VICTOR is a randomized, double-blind, placebo-controlled, multicenter, 2-part study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and antiviral effect of single and multiple dosing of AK0529 in infants hospitalized with RSV infection.

NCT ID: NCT02654041 Terminated - Clinical trials for Glioblastoma Multiforme (GBM)

Study of Induction of Hypothyroxinemia Adjunct to Conventional Therapies in GBM Patients

Start date: March 2016
Phase: Phase 2
Study type: Interventional

The objective of the study is to assess the safety and efficacy of treatment with hypothyroxinemia adjunct to conventional therapies in GBM patients.

NCT ID: NCT02653820 Not yet recruiting - Reflexology Clinical Trials

Complementary Effect of Reflexology on Chemotherapy-Induced Nausea and Vomiting

Start date: February 2016
Phase: Phase 2
Study type: Interventional

Reflexology treatment may influence the severity of chemotherapy-induced nausea and vomiting. This study aims to investigate the clinical effect of reflexology on chemotherapy-induced nausea and vomiting.

NCT ID: NCT02653300 Completed - Clinical trials for Type2 Diabetes Mellitus

A Pilot Study to Assess the Safety of Oral Insulin in Patients With Nonalcolholic Steatohepatitis (NASH)

Start date: September 20, 2018
Phase: Phase 2
Study type: Interventional

This is an open, pilot study using the oral ORMD-0801 insulin formulation in patients with NASH and confirmed type 2 DM or pre-diabetes. The study will consist of a Screening, placebo run-in, treatment phase and end-of-study phase.

NCT ID: NCT02652689 Terminated - Pulmonary Embolism Clinical Trials

Diagnosis of Pulmonary Embolism by Doppler Signals

Start date: April 2016
Phase: N/A
Study type: Interventional

The LDS may contain information of significant diagnostic and physiological value regarding the pulmonary parenchyma and vasculature, as well as the cardio- vascular system in general. In pilot clinical studies of patients with acute decompensated heart failure (ADHF) as well as patients with Pulmonary Hypertension, LDS signals patterns unique to these conditions were identified. We believe that these newly discovered ultrasound signals might provide a non-invasive radiation-free means to diagnose and monitor patients with Pulmonary Embolism. The purpose of this study is to assess the utility of noninvasive assessment of lung Doppler signals performed via transthoracic parametric Doppler. The objective of the study is to evaluate the lung Doppler signals (LDS) in patients diagnosed with acute PE, in order to determine the potential assessment value of this non-invasive method in this potentially life threatening condition.

NCT ID: NCT02652481 Completed - Clinical trials for Magnetic Resonance Imaging

ENABLE MRI (Magnetic Resonance Imaging)

ENABLE-MRI
Start date: January 2016
Phase: N/A
Study type: Interventional

The objective of this study is to collect data to confirm the safety and effectiveness of the Image Ready™ MR (Magnetic Resonance) Conditional Defibrillation System when used in the 1.5T (Tesla) MRI environment under the labeled Conditions of Use (Phase I). Additionally, the study will assess medically necessary MR scans according to the labeled Conditions of Use to provide real-world scanning data (Phase I and Phase II).The study also aims to demonstrate the continued ability of the ImageReady MR Conditional Defibrillation System to sense and detect ventricular fibrillation (VF) post MRI scan by collecting and analyzing data from spontaneous VF episodes, "for-cause" VF inductions, and from an optional VF induction Sub-study. .

NCT ID: NCT02651181 Completed - Type 1 Diabetes Clinical Trials

Feasibility Study to Evaluate the Hybrid-Logic Closed Loop System in Type 1 Diabetes The DREAMED Trail

Start date: June 2016
Phase: N/A
Study type: Interventional

Closed loop technology has been shown to reduce both hypoglycemia and hyperglycemia, as well as reduce glycemic variability. Several groups around the world investigate efforts in developing closed-loop systems. Investigators combined two closed-loop systems with different mode of operation in order to enhance the closed-loop system. The two systems are Hybrid closed-loop system and the MD-Logic closed-loop system . The combined algorithm Hybrid logic closed loop (HLCL) was tested 'In silico' and was proved to be safe and effective. The next step is to test the system in a clinical study in a supervised environment in a camp. The two systems were tested separately in several clinical studies and were proven to be safe and effective in a diverse population of patients with type 1 diabetes. The MD-Logic system for overnight use "the GlucoSitter" has a CE mark. The purpose of this study is to collect data on the feasibility of the HLCL system in a camp setting.

NCT ID: NCT02649413 Not yet recruiting - Clinical trials for Nephrotic Syndrome, Minimal Change

Adjusted Steroids Therapy in Childerens With Idiopathic Nephrotic Syndrome

AJSNS
Start date: March 2016
Phase: Phase 4
Study type: Interventional

The initial steroids dose for Nephrotic Syndrome is 60mg/1m2 for 6-4 weeks and the duration of the first steroid course is between 8 weeks to 6 months. The base of the initial dose for steroids Idiopathic nephrotic syndrome been put in the early 70s. In our study the investigators will adjusted the first steroids does to the response day. Our primary end point is : a lower adjusted dose is as good as the fix dose in the first year after diagnosis.

NCT ID: NCT02649374 Completed - Clinical trials for Gestational Diabetes Mellitus

Gut Microbiome and Gestational Diabetes Mellitus

Start date: February 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to document the gut microbiome in the 1st, 2nd and 3rd trimester among pregnant women with gestational diabetes and non diabetic controls.

NCT ID: NCT02648347 Completed - Anemia Clinical Trials

Study to Evaluate Vadadustat for the Correction of Anemia in Participants With Non-dialysis-dependent Chronic Kidney Disease

Start date: December 2015
Phase: Phase 3
Study type: Interventional

A multicenter, randomized, open-label, active-controlled Phase 3 study for the correction of anemia and maintenance of hemoglobin (Hb) in participants with Non-Dialysis-Dependent Chronic Kidney Disease (NDD-CKD)