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NCT ID: NCT02762968 Completed - Military Training Clinical Trials

The Effects of Probiotic and HMB Supplementation on Immune and Digestive Function in Special Operations Soldiers

Start date: April 2016
Phase: N/A
Study type: Interventional

The study will determine whether acute ingestion of a probiotic combined with beta-hydroxy-beta-methylbutyrate (HMB) can enhance immune and digestive function in soldiers during 8-weeks of advanced infantry training.

NCT ID: NCT02761356 Completed - Clinical trials for Primary Liver Tumor, Metastatic Liver

The Added Value of Hybrid Functional Anatomical Imaging PET-CT and SPECT-CT in Patients Treated With Y-90 SIRT for Liver Malignancies

Start date: January 2010
Phase: N/A
Study type: Observational

Patients cohort is composed of 50 consecutive patients both male and female with hepatic malignancies, refered to our nuclear medicine department in the process of radioembolization between January 2010- August 2015. 26 of the patients were examined with Tc99-MAA and SPECT-CT and 24 patients were examined with Tc99-MAA , SPECT-CT and PET-CT. Our study protocol was as follows: 1. Collection of anamnestic data 2. Calculation of liver tumor volume with quantification software 3. Evaluation of the liver tumor involvement 4. Evaluation of liver to lung shunt 5. Calculation dose of SIRTEX 6. Y90 imaging 7. Follow Up

NCT ID: NCT02761187 Completed - Multiple Myeloma Clinical Trials

An Observational Study of Presentation, Treatment Patterns, and Outcomes in Multiple Myeloma Participants

Start date: July 1, 2016
Phase:
Study type: Observational

The purpose of this study is to describe contemporary, real-world patterns of patient characteristics, clinical disease presentation, therapeutic regimen chosen, and clinical outcomes in participants with newly diagnosed [ND] multiple myeloma (MM) and participants with relapsed/refractory [R/R] MM.

NCT ID: NCT02760277 Completed - Clinical trials for Duchenne Muscular Dystrophy

An Extension Study to Assess Vamorolone in Boys With Duchenne Muscular Dystrophy (DMD)

Start date: July 28, 2016
Phase: Phase 2
Study type: Interventional

The main purposes of this study are to see if it is safe to use a new medication called vamorolone for more than two weeks in children with Duchenne muscular dystrophy (DMD), to see if vamorolone works for the treatment for DMD, and to see how any potential side effects compare to those seen in boys using steroids.

NCT ID: NCT02760264 Completed - Clinical trials for Duchenne Muscular Dystrophy

A Study to Assess Vamorolone in Boys With Duchenne Muscular Dystrophy (DMD)

Start date: June 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether a new medication called vamorolone is safe and well-tolerated by boys with Duchenne muscular dystrophy (DMD) ages ≥ 4 and < 7 years old.

NCT ID: NCT02756611 Completed - Clinical trials for Chronic Lymphocytic Leukemia

A Study to Evaluate the Efficacy of Venetoclax Monotherapy in Relapsed/Refractory Participants With Chronic Lymphocytic Leukemia (CLL)

VENICE I
Start date: June 22, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of venetoclax monotherapy in participants with relapsed/refractory CLL with or without the 17p deletion or TP53 mutation, including those who have received prior treatment with a B-cell receptor inhibitor.

NCT ID: NCT02756221 Completed - Gastroenteritis Clinical Trials

Probiotic Supplementation and Endurance Performance in Cyclists and Masters Runners

Start date: March 2016
Phase: N/A
Study type: Interventional

The study will evaluate the change in gastrointestinal (GI) flora following probiotic supplementation, and expected to lead to an increase in the intestinal epithelial integrity and to improvement in its health. Concurrently with the reduction in the amount of toxins in the GI tract following an intensive exercise, a lower incidence of symptoms of discomfort will improve the quality of the training sessions which will be exhibited by an improvement in endurance capacity and in physiological responses to rigorous exercise. Half of the participants will receive probiotic supplement while the other half will receive a placebo.

NCT ID: NCT02753127 Completed - Colorectal Cancer Clinical Trials

A Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal Cancer

CanStem303C
Start date: June 2016
Phase: Phase 3
Study type: Interventional

This is an international multi-center, prospective, open-label, randomized, adaptive design phase 3 trial of the cancer stem cell pathway inhibitor napabucasin plus standard bi-weekly FOLFIRI versus standard bi-weekly FOLFIRI in patients with previously treated metastatic colorectal cancer (CRC).

NCT ID: NCT02752776 Completed - Plaque Psoriasis Clinical Trials

A Study to Evaluate Clear Skin Effect on Quality of Life in Patients With Plaque Psoriasis.

PROSE
Start date: March 17, 2016
Phase: Phase 4
Study type: Interventional

Study of effects of secukinumab 300 mg s.c. on quality of life (QoL) in psoriasis in patients with or without prior exposure to systemic therapy.

NCT ID: NCT02752074 Completed - Melanoma Clinical Trials

A Phase 3 Study of Pembrolizumab + Epacadostat or Placebo in Subjects With Unresectable or Metastatic Melanoma (Keynote-252 / ECHO-301)

Start date: June 21, 2016
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess the efficacy, safety, and tolerability when combining pembrolizumab with epacadostat or placebo in participants with unresectable or metastatic melanoma