Clinical Trials Logo

Filter by:
NCT ID: NCT01208090 Completed - Psoriasis Clinical Trials

ACT-128800 in Patients With Moderate to Severe Chronic Plaque Psoriasis

Start date: October 31, 2010
Phase: Phase 2
Study type: Interventional

This study will assess the efficacy, safety and tolerability of two doses of ACT 128800 in patients with moderate-to-severe chronic plaque psoriasis.

NCT ID: NCT01205737 Completed - DLBCL Clinical Trials

A Double-blind, Randomized Controlled Study in CD20-positive Diffuse B Cell Non-Hodgkin's Lymphoma Subjects

Start date: September 2010
Phase: Phase 1
Study type: Interventional

This is a prospective international, multi-center, randomized, double-blind controlled study designed to assess and compare the pharmacokinetics, pharmacodynamics and the safety of MabThera® and TL011, in combination with CHOP in previously untreated patients with diffuse large B cell lymphoma.

NCT ID: NCT01205438 Completed - Clinical trials for Systemic Lupus Erythematosus

A Study of LY2127399 in Participants With Systemic Lupus Erythematosus

Start date: January 2011
Phase: Phase 3
Study type: Interventional

The purpose of this SLE study is to evaluate the efficacy, safety and tolerability of two different doses of LY2127399 administered in addition to standard of care therapy in participants with active SLE.

NCT ID: NCT01204710 Completed - Prostate Cancer Clinical Trials

A Study of Olaratumab (IMC-3G3) in Prostate Cancer

Start date: October 2010
Phase: Phase 2
Study type: Interventional

This is a study evaluating the safety and efficacy of the monoclonal antibody olaratumab plus mitoxantrone plus prednisone compared to mitoxantrone plus prednisone in metastatic castration-refractory prostate cancer following disease progression or intolerance on docetaxel-based chemotherapy.

NCT ID: NCT01203631 Completed - Inflammation Clinical Trials

Safety and Efficacy of NNC 0142-0000-0002 in Subjects With Moderately to Severely Active Crohn's Disease

Start date: February 2011
Phase: Phase 2
Study type: Interventional

This trial is conducted in Europe and North America. The aim of the trial is to assess disease activity and safety in subjects with moderately to severely active Crohn's disease (CD) when treated with NNC 0142-0000-0002.

NCT ID: NCT01203605 Completed - Non-cardiac Surgery Clinical Trials

European Surgical Outcomes Study

EuSOS
Start date: April 2011
Phase: N/A
Study type: Observational

The European Surgical Outcomes Study (EuSOS) is a multi-centre, international cohort study of peri-operative care and clinical outcomes for patients undergoing non-cardiac surgery. Participating centres throughout Europe will contribute routine clinical data describing all eligible patients who undergo surgery from 4th April 2011 to 11th April 2011. Patients will then be followed until hospital discharge (or for a maximum of 60 days) for duration of hospital stay and hospital mortality. Routine clinical data will also be collected for those patients admitted to critical care at any stage after surgery but during the same hospital admission. Specific objectives are to describe clinical outcomes and standards of peri-operative care for patients undergoing non-cardiac surgery in Europe.

NCT ID: NCT01202760 Completed - Clinical trials for Rheumatoid Arthritis

A Rheumatoid Arthritis Study in Participants

FLEX O
Start date: January 2011
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to help answer if LY2127399 is safe and effective in the treatment of rheumatoid arthritis with or without background disease-modifying anti-rheumatic drug (DMARD) therapy. This study is comprised of 2 periods: Period 1 - 24-week blinded treatment Period 2 - 48-week post-treatment follow-up

NCT ID: NCT01202617 Completed - Clinical trials for Relapse in Schizophrenia

Seroquel XR in the Long Term Treatment of Schizophrenia

SereNIS
Start date: September 2010
Phase: N/A
Study type: Observational

The purpose of the study is to determine whether the Seroquel XR treatment for 6 months improves the relapse prevention in schizophrenic outpatients

NCT ID: NCT01202591 Completed - ER+ Breast Cancer Clinical Trials

Safety and Efficacy of AZD4547 in Combination With Fulvestrant vs. Fulvestrant Alone in ER+ Breast Cancer Patients

GLOW
Start date: December 2010
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and effectiveness of AZD4547 in combination with fulvestrant vs. fulvestrant alone in ER+ breast cancer patients with FGFR1 polysomy (FISH4/5) or gene amplification (FISH 6)

NCT ID: NCT01202565 Completed - Clinical trials for Moderate to Severe Plaque Psoriasis

Effectiveness of Adalimumab (HUMIRA®) in the Treatment of Scalp and Nail Affection in Patients With Moderate to Severe Plaque Psoriasis in Routine Clinical Practice

Start date: September 2010
Phase: N/A
Study type: Observational

There is clearly a need for further data on the efficacy of biologic agents in the treatment of nail and scalp psoriasis, especially in the routine clinical setting. A few case reports can be found, but no published data exists from non-interventional studies, such as post-marketing observational studies (PMOS) that reflect routine clinical practice. The aim of this PMOS is to evaluate the long-term (12-month) efficacy of adalimumab in the treatment of nail and scalp psoriatic lesions in routine dermatologic practice.