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NCT ID: NCT01564784 Completed - Clinical trials for Acute Lymphoblastic Leukemia

A Study Of Inotuzumab Ozogamicin Versus Investigator's Choice Of Chemotherapy In Patients With Relapsed Or Refractory Acute Lymphoblastic Leukemia

Start date: August 2, 2012
Phase: Phase 3
Study type: Interventional

This study will compare the efficacy, in terms of complete responses and overall survival, of inotuzumab ozogamicin versus investigator's choice of chemotherapy.

NCT ID: NCT01561456 Completed - Clinical trials for Squamous Cell Carcinoma

Study of AXL1717 Compared to Docetaxel to Treat Squamous Cell Carcinoma or Adenocarcinoma of the Lung

Start date: December 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare effectiveness and safety of experimental anticancer medicine, AXL1717, and docetaxel in patients with squamous cell carcinoma or adenocarcinoma of the lung.

NCT ID: NCT01559116 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Characterization of 24-hour Lung Function Profiles of Inhaled Tiotropium + Olodaterol Fixed Dose Combination in Patients Suffering From Chronic Obstructive Pulmonary Disease

Start date: March 2012
Phase: Phase 3
Study type: Interventional

The primary objective of the trial is to determine the 24-hour FEV1-time profile of tiotropium + olodaterol FDC, administered once daily by the RESPIMAT Inhaler after 6 weeks of treatment.

NCT ID: NCT01558102 Completed - Brain Aneurysms Clinical Trials

International Retrospective Study of Pipeline Embolization Device

IntrePED
Start date: March 2012
Phase: N/A
Study type: Observational

The primary objective of this retrospective study is to determine the incidence of important safety outcomes in patients who have undergone Pipeline Embolization Device placement for intracranial aneurysms (IAs). This study does not effect patient care, simply it is designed to observe and capture information from numerous hospitals. Data collection will be initiated starting March 2012 and continue until approximately April 2017.

NCT ID: NCT01556893 Completed - Myopia Clinical Trials

Creating LASIK Flaps With the LenSx Femtosecond Laser

Start date: April 2012
Phase: Phase 1
Study type: Interventional

This will be a prospective, single-center clinical trial of up to 50 eyes of subjects scheduled to undergo LASIK surgery requiring an initial corneal flap. Subjects will be screened for eligibility. Subjects will undergo LASIK surgery using the LenSx Laser to create the corneal flap prior to excimer laser treatment. Subjects will be evaluated intraoperatively to assess the ease of lifting the flaps, the stromal bed quality, and the amount of opaque bubble layer. All patients will be followed with routine vision exams for 3 months postoperatively to evaluate changes in visual acuity, manifest refraction, slit lamp examination, and endothelial cell counts.

NCT ID: NCT01555164 Completed - Clinical trials for Type 2 Diabetes Mellitus

A Phase 3 Study of Ranolazine in Subjects With Type 2 Diabetes Who Are Inadequately Controlled on Metformin Alone

Start date: June 2012
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, placebo-controlled, parallel-group, multicenter study to determine the effect of ranolazine when added to metformin on glycemic control in adults with type 2 diabetes mellitus (T2DM) who are inadequately controlled despite current treatment with stable metformin therapy in addition to diet and exercise.

NCT ID: NCT01555151 Completed - Asthma Clinical Trials

Safety and Efficacy of Mometasone Furoate Delivered Via Concept1 Device or Twisthaler® Device in Adult and Adolescent Patients With Persistent Asthma

Start date: July 2012
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the efficacy, safety and pharmacokinetics of Mometasone furoate delivered via Concept1 device or Twisthaler® device in adult and adolescent patients with persistent asthma.

NCT ID: NCT01555099 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Multi-centre Study to Assess the Efficacy and Safety of AZD5423 in COPD Patients on a Background Therapy of Formoterol

Start date: April 2012
Phase: Phase 2
Study type: Interventional

The purpose of the study is to assess the efficacy and safety of two staggered dose levels of inhaled once daily AZD5423 or twice daily budesonide for 12 weeks in COPD patients on a background therapy of formoterol.

NCT ID: NCT01554696 Completed - Clinical trials for Arthritis, Rheumatoid

A Study to Evaluate the Safety and Efficacy of ASP015K in Moderate to Severe Rheumatoid Arthritis Subjects Who Have Had an Inadequate Response to Methotrexate

Start date: July 6, 2012
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of ASP015K in moderate to severe rheumatoid arthritis subjects who are methotrexate-inadequate responders (MTX-IR).

NCT ID: NCT01554618 Completed - Clinical trials for Children and Adolescent With Type 2 Diabetes

Safety and Efficacy Study of Exenatide Once Weekly in Adolescents With Type 2 Diabetes

Start date: December 2, 2011
Phase: Phase 3
Study type: Interventional

The study examines the Safety and efficacy study of exenatide once weekly in children and adolescents with type 2 diabetes