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NCT ID: NCT04793854 Completed - Sickle Cell Disease Clinical Trials

Sickle Cell Disease, Neurocognitive Disorders, Social Participation

SOCIODREP
Start date: September 19, 2018
Phase:
Study type: Observational

This project will promote the development of transdisciplinary analyses. Neuropsychological disorders will be explored with the usual appropriate tests done by psychologists and neuropsychologists regularly involved in the management of sickle cell disease affected children. For the social sciences' component, various methods will be used: Measure of the Life habits (MHAVIE), Measure of Environmental Quality (MQE) and semi-guided interviews will complete the collection of qualitative data. The expected results concern the identification of the barriers or facilitators the sickle cell patients might face in their social participation, whether they are affected or not by neurological disorders.

NCT ID: NCT04707235 Recruiting - Sickle Cell Disease Clinical Trials

ESCORT-HU Extension: European Sickle Cell Disease Cohort - Hydroxyurea - Extension Study

Start date: August 21, 2020
Phase:
Study type: Observational

As safety information pertaining to the long-term use of HU remains incomplete in spite of the first safety study (ESCORT-HU), an extension of the latter is proposed. ESCORT-HU Extension study aims at evaluating the long-term safety of Siklos® focusing on some questions regarding its safety when used in current practice in adults and paediatric patients treated with Siklos® and followed for up to 5 years. The study will focus on the following concerns : occurrence and incidence of malignancies, leg ulcers, male fertility impairment and serious unexpected AEs causally related to Siklos®.

NCT ID: NCT04647682 Completed - COVID-19 Infection Clinical Trials

Physical Activity Program Implementation in Hospitalized Positive COVID-19 Older Adults

Cov-activity
Start date: January 5, 2021
Phase:
Study type: Observational

Our hypothesis was that physical activity program will be acceptable and may counteract physical and mental decline among older adults hospitalized in COVID-19 unit

NCT ID: NCT04587466 Recruiting - Geriatric Syndromes Clinical Trials

KArukera Study of Aging in Nursing Homes

KASEHPAD
Start date: November 3, 2020
Phase:
Study type: Observational

Nursing homes are a recent occurrence in Guadeloupe, and little is known about the characteristics of their residents. In Guadeloupe, in the French West Indies, nearly 1200 dependent older people are cared for in nursing homes. The aim of the KArukera Study of Aging in Nursing Homes (KASEHPAD) is to study the care pathways of dependent elderly people in nursing homes in Guadeloupe over a year. The main objective will be to obtain the annual rate of hospitalisation in this setting. The secondary objectives will be to assess hospitalisations costs, the incidence of mortality, the prevalence of geriatric syndromes, as well as the quality of life of residents and professional caregiver burnout. Ultimately, these results will be compared to a similar study in nursing homes, the KASAF study (for Karukera Study of Aging in Foster Families).

NCT ID: NCT04545775 Recruiting - Geriatric Syndromes Clinical Trials

KArukera Study of Ageing in Foster Families

KASAF
Start date: November 13, 2020
Phase:
Study type: Observational

Foster care for dependent older people could be a viable alternative to nursing homes. While this type of accommodation appears to be less expensive than living in a geriatric institution, few scientific studies have been able to assess its effectiveness and efficiency. In Guadeloupe, in the French West Indies, nearly 300 dependent older people are cared for by foster families. The aim of the Karukera Study of Ageing in Foster Families (KASAF) is to study the care pathways of dependent elderly people in foster care over a year. The main objective will be to obtain the annual rate of hospitalisation in this setting. The secondary objectives will be to assess hospitalisations costs, the incidence of mortality, the prevalence of geriatric syndromes, as well as the quality of life of residents and foster caregiver burnout. Ultimately, these results will be compared to a similar study in nursing homes, the KASEHPAD study (for Karukera Study of Aging in Nursing Homes).

NCT ID: NCT04459169 Recruiting - Cardiac Amyloidosis Clinical Trials

Cardiac Amyloidosis : Diagnostic Using Red Flag Signals

TEAM Red Flags
Start date: September 30, 2020
Phase:
Study type: Observational

Cardiac amyloidosis is an increasingly contributor of degenerative cardiac diseases. However, its frequency remains underestimated, and diagnosis is often realized at late stages of the disease. A larger use of clinical and echographic Red Flag signals during routine echocardiographic examination may enhance the identification of early stage of the disease.

NCT ID: NCT04455919 Terminated - Clinical trials for Chikungunya Virus Infection

Yoga for Chronic Chikungunya

YOCHIK
Start date: October 3, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the benefits of a 8-week yoga program on quality of life in patients suffering from chronic chikungunya. Studies have already shown the effectiveness of yoga practice on various arthralgia's, on the reduction of inflammatory reactions, on psychological disorders/sleep disorders and on quality of life. Considering quality of life as a global experience of balance between physical and mental wellbeing, the hypothesis was that the practice of yoga would globally improve the quality of life of patients with chronic chikungunya.

NCT ID: NCT04414319 Terminated - SARS-CoV 2 Clinical Trials

Severe Acute Respiratory Syndrome-Coronavirus-2 and Loss of Autonomy in the Elderly

CovAged
Start date: April 15, 2020
Phase:
Study type: Observational

In most diseases, older people have less typical symptomatology than that described for younger people. The investigators therefore hypothesize that within the framework of coronavirus disease 19, the clinical pictures in the elderly will present specificities that will need to be described. Moreover, since infection by the severe acute respiratory syndrome (SARS-CoV-2) virus is new to humans, the investigators do not yet have sufficient information on the fate of the elderly, in terms of loss of autonomy, rehospitalization, institutionalization, mortality, etc. the investigators therefore assume that the clinical pictures in the elderly will present specificities that will need to be described. The investigators hypothesize that an acute infection of this type will have short-, medium-, and long-term repercussions in the elderly.

NCT ID: NCT04328129 Completed - SARS-CoV Infection Clinical Trials

Household Transmission Investigation Study for COVID-19 in Tropical Regions

EPI-COVID-19
Start date: March 23, 2020
Phase: N/A
Study type: Interventional

This study is a interventional study that present minimal risks and constraints to evaluate the presence of novel coronavirus (SARS-CoV-2) or antibodies among individuals living in households where there is a confirmed coronavirus case in order to provide useful information on the proportion of symptomatic forms and the extent of the virus transmission in tropical regions such as French Guiana, Guadeloupe and New-Caledonia.

NCT ID: NCT04307056 Completed - Prostate Cancer Clinical Trials

Evaluation of HIFU in TREATMENT OF LOCALIZED PROSTATE CANCER and OF RECURRENCE AFTER RADIOTHERAPY

HIFI
Start date: March 23, 2015
Phase: N/A
Study type: Interventional

to compare the efficacy of HIFU treatment with standard treatment in two situations: 1. as first-line cancer treatment, HIFU is compared to radical prostatectomy. 2. for patients with recurrence after external beam radiotherapy, HIFU treatment is compared to radical prostatectomy.