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NCT ID: NCT04974710 Completed - Endometriosis Clinical Trials

Developing an US-MRI Biomarker Fusion Model for Endometriosis

DEFEND
Start date: March 18, 2022
Phase:
Study type: Observational

Single centre, prospective, observational, cohort study looking to develop a database representing the variability of disease and imaging seen in women with clinically diagnosed endometriosis, awaiting laparoscopic surgery.

NCT ID: NCT04973449 Completed - COVID-19 Clinical Trials

Phase II/III Study of AZD2816, for the Prevention of COVID-19 in Adults

AZD2816
Start date: June 27, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of the study is to assess the safety, and immunogenicity of AZD2816 for the prevention of COVID-19

NCT ID: NCT04972812 Completed - Ischemic Stroke Clinical Trials

The Effects of Posture on Cerebral Blood Flow Velocity During the Acute Phase of Stroke

Start date: July 1, 2021
Phase:
Study type: Observational

After stroke, blood vessels in the brain can become damaged, and the brain's ability to control blood flow can be impaired. The brain therefore may be less able to maintain a healthy level of blood flow during challenges such as changes in posture. Studies have shown that sitting upright early after stroke can cause brain blood flow to reduce. However, no studies have investigated how standing up affects blood flow to the brain. In this study, transcranial Doppler ultrasound will be used to assess how cerebral blood flow velocity changes when acute stroke patients stand up.

NCT ID: NCT04972266 Completed - Clinical trials for Hemodynamic Monitoring

The EU Hyprotect Registry

Start date: September 28, 2021
Phase:
Study type: Observational [Patient Registry]

European, multicenter, prospective, observational registry in patients undergoing elective major non-cardiac surgery

NCT ID: NCT04971460 Completed - Clinical trials for Mental Health Disorder

The Mental Well-being of Fathers and Partners

Start date: July 24, 2021
Phase:
Study type: Observational

The purpose of this study is to assess the acceptability and feasibility of screening common mental health difficulties in fathers and partners of women accessing perinatal mental health services.

NCT ID: NCT04970407 Completed - Clinical trials for Healthy Participants

A Comparative Study to Evaluate the Effects and Mechanism of Action of Dysport®, Botox® and Xeomin® in the Extensor Digitorum Brevis Model in Healthy Adult Male Participants

Start date: July 6, 2021
Phase: Phase 1
Study type: Interventional

Study aimed at comparing the pharmacodynamic profile (including duration of action) of three commercialized toxins by measuring the action potential of the injected muscle (extensor digitorum brevis)

NCT ID: NCT04970394 Completed - Clinical trials for Physician-Patient Relations

An Observational Study of GP Verbal Reminders Upon Cervical Screening

VRCS
Start date: March 1, 2017
Phase:
Study type: Observational [Patient Registry]

Cervical cancer screening is offered to all women in the United Kingdom (UK) between the ages of 24.5 and 64 years of age. The majority of screening is performed in primary care and the rate remains stubbornly below 80%, despite an automated national invitation system. This study is designed to assess the effectiveness of a physician invitation during a telephone or face-to-face primary care appointment upon non responders of automated invitations, to increase the uptake of cervical screening.

NCT ID: NCT04969653 Completed - Atopic Dermatitis Clinical Trials

The Incidence of Venous Thromboembolism in Atopic Dermatitis

Start date: June 21, 2021
Phase:
Study type: Observational

This study aims to investigate the incidence of venous thromboembolism in people who are diagnosed with atopic dermatitis.

NCT ID: NCT04969419 Completed - Melanoma (Skin) Clinical Trials

Incidence of Melanoma and Non-melanoma Skin Cancer in People With Vitiligo

Start date: June 18, 2021
Phase:
Study type: Observational

This study examines melanoma and nonmelanoma skin cancer in people diagnosed with vitiligo compared to matched controls.

NCT ID: NCT04966741 Completed - Clinical trials for Bardet-Biedl Syndrome

Setmelanotide in Pediatric Patients With Rare Genetic Diseases of Obesity

Start date: February 16, 2022
Phase: Phase 3
Study type: Interventional

This is a phase 3 open-label, one-arm, clinical study to evaluate the efficacy, safety and tolerability of setmelanotide over 1 year of treatment, in pediatric patients aged 2 to <6 years with obesity due to either biallelic variants of the POMC, PCSK1 or LEPR genes or Bardet-Biedl Syndrome (BBS).